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N-(2,5-dimethylpyrrol-1-yl)pyridine-4-carboxamide

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Identification
Molecular formula
C12H14N2O
CAS number
222455-10-3
IUPAC name
N-(2,5-dimethylpyrrol-1-yl)pyridine-4-carboxamide
State
State

This compound is in a solid state at room temperature.

Melting point (Celsius)
150.00
Melting point (Kelvin)
423.15
Boiling point (Celsius)
340.00
Boiling point (Kelvin)
613.15
General information
Molecular weight
214.27g/mol
Molar mass
214.2680g/mol
Density
1.2000g/cm3
Appearence

The compound appears as a solid crystalline powder, typically off-white to pale yellow in color.

Comment on solubility

Solubility of N-(2,5-dimethylpyrrol-1-yl)pyridine-4-carboxamide

The solubility of N-(2,5-dimethylpyrrol-1-yl)pyridine-4-carboxamide can be influenced by several fascinating factors. This compound contains both a pyridine and a carboxamide functional group, which suggests specific interactions with solvents. Here are some key points regarding its solubility:

  • Polarity: The presence of the polar carboxamide group often leads to increased solubility in polar solvents, such as water. This can enhance the compound’s interaction with dipole molecules.
  • Hydrogen Bonding: The potential for hydrogen bonding due to the amide functionality may also facilitate solubility in alcohols and other protic solvents.
  • Structural Considerations: The 2,5-dimethyl substitutions on the pyrrol ring may affect the overall spatial arrangement, potentially impacting solubility. Bulkier groups can hinder interactions with solvents.
  • Solvent Choice: This compound may have limited solubility in non-polar solvents due to its polar characteristics. Commonly used solvents can include dimethyl sulfoxide (DMSO) and dimethylformamide (DMF).

In general, it can be anticipated that the solubility profile of N-(2,5-dimethylpyrrol-1-yl)pyridine-4-carboxamide will be favorable in polar environments, while caution should be exercised when testing in non-polar conditions. The interplay between its structural features and the solvent environment ultimately dictates its solubility behavior.

Interesting facts

N-(2,5-Dimethylpyrrol-1-yl)pyridine-4-carboxamide

This intriguing compound has garnered attention in various fields, particularly in medicinal chemistry and agrochemistry. Here are some fascinating points about N-(2,5-dimethylpyrrol-1-yl)pyridine-4-carboxamide:

  • Biological Significance: This compound exhibits significant biological activity, making it a valuable focal point in drug development. Its role as a potential drug candidate in treating various ailments is under investigation.
  • Diverse Applications: Beyond pharmaceuticals, this compound has also found applications in the agrochemical industry, where it may serve as an effective herbicide or pesticide, showcasing its versatility.
  • Structural Features: The unique structure integrates pyridine and pyrrolidine rings, imparting distinct chemical properties. The presence of the dimethyl group enhances its stability and reactivity.
  • Potential for Derivation: Chemists are exploring various derivatives of this compound. Modifications to its structure could lead to new compounds with enhanced potency and selectivity.
  • Research Opportunities: Current research includes the compound's mechanism of action and its interaction with biological targets, which could reveal important insights for future applications.

As scientists continue to unravel the intricacies of N-(2,5-dimethylpyrrol-1-yl)pyridine-4-carboxamide, it's clear that its potential is just beginning to be realized. The ongoing exploration of this compound underscores the importance of chemical research in addressing contemporary challenges in health and agriculture.

Synonyms
5588-11-4
SQ 3242
N-(2,5-Dimethylpyrrol-1-yl)isonicotinamide
BRN 0188855
DTXSID10204476
1-Isonicotinylamino-2,5-dimethylpyrrole [French]
ISONICOTINAMIDE, N-(2,5-DIMETHYLPYRROL-1-YL)-
1-Isonicotinylamino-2,5-dimethylpyrrole
4-Pyridinecarboxamide, N-(2,5-dimethyl-1H-pyrrol-1-yl)-
4-22-00-00560 (Beilstein Handbook Reference)
DTXCID10126967
N-(2,5-dimethylpyrrol-1-yl)pyridine-4-carboxamide
N-(2,5-dimethyl-1H-pyrrol-1-yl)isonicotinamide
N-(2,5-dimethyl-1H-pyrrol-1-yl)pyridine-4-carboxamide
MFCD01717893
1-(4-Pyridoyl)amino-2,5-dimethylpyrrole
Bionet2_001173
CHEMBL3091886
HMS1367F07
AKOS000104076
8T-0837