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Clonidine hydrochloride

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Identification
Molecular formula
C9H10Cl2N3 \cdot HCl
CAS number
54544-14-8
IUPAC name
N-[(2,6-dichlorophenyl)methyleneamino]-4,5-dihydro-1H-imidazol-1-ium-2-amine;chloride
State
State

At room temperature, Clonidine hydrochloride is typically a solid.

Melting point (Celsius)
176.00
Melting point (Kelvin)
449.15
Boiling point (Celsius)
235.00
Boiling point (Kelvin)
508.00
General information
Molecular weight
266.57g/mol
Molar mass
266.5660g/mol
Density
1.3000g/cm3
Appearence

Clonidine hydrochloride typically appears as a white or slightly off-white crystalline powder. It may also appear in crystalline solid form.

Comment on solubility

Solubility of N-[(2,6-dichlorophenyl)methyleneamino]-4,5-dihydro-1H-imidazol-1-ium-2-amine;chloride

The solubility of N-[(2,6-dichlorophenyl)methyleneamino]-4,5-dihydro-1H-imidazol-1-ium-2-amine;chloride is an intriguing topic of investigation. This compound, characterized by its complex structure, exhibits varied solubility profiles depending on several factors. Here are some key considerations:

  • Polarity: The presence of functional groups can influence the overall polarity of the compound. The imidazolium and amine groups likely provide partial positive charges, suggesting potential water solubility.
  • Presence of Chloride: The ionic nature of the chloride counterion typically enhances solubility in polar solvents, particularly in aqueous environments.
  • Hydrophobic Interactions: The dichlorophenyl moiety can introduce hydrophobic characteristics, affecting solubility in non-polar solvents.

It is important to note that the solubility can be represented through the following parameters:

  1. Solvent Type: The solubility may be much higher in polar solvents such as water or ethanol.
  2. Concentration: Increased temperatures or concentrations may improve solubility due to enhanced molecular interactions.
  3. pH Levels: The solubility might vary significantly when the pH of the solution is adjusted, particularly around physiological pH levels.

In conclusion, the solubility of N-[(2,6-dichlorophenyl)methyleneamino]-4,5-dihydro-1H-imidazol-1-ium-2-amine;chloride is influenced by a multitude of factors, making it a compound of interest for further study in various solvent systems.

Interesting facts

Interesting Facts about N-[(2,6-Dichlorophenyl)methyleneamino]-4,5-dihydro-1H-imidazol-1-ium-2-amine; Chloride

This compound, known for its complex structure, has attracted attention due to its potential applications in various fields such as pharmaceuticals and agrochemicals. Here are some fascinating insights about its properties and importance:

  • Application in Drug Development: The imidazolium core is a significant feature in medicinal chemistry. Compounds containing an imidazolium structure are often explored for their potential therapeutic effects, making this particular compound an interesting candidate for research.
  • Antimicrobial Properties: Compounds similar to this one have shown promising results in antimicrobial studies. The presence of the dichlorophenyl group may enhance its efficacy against various pathogens, paving the way for potential use in infection control.
  • Versatile Synthetic Routes: The synthesis of this compound can involve various intricate pathways that are of great interest to chemists. Understanding these synthetic methodologies can provide insight into organic synthesis and catalysis.
  • Unique Reactivity: The presence of the imidazolium cation may contribute to unique reactivity patterns, including interactions with nucleophiles. This can be crucial in developing novel reactions and understanding mechanism pathways.
  • Potential Side Effects: While exploring its potential uses, it is equally important to consider possible side effects or toxicity. Comprehensive studies are essential to ensure safety and efficacy in practical applications.

Overall, N-[(2,6-Dichlorophenyl)methyleneamino]-4,5-dihydro-1H-imidazol-1-ium-2-amine; chloride represents a fascinating area of study in chemistry with implications for future research that could have significant impacts.