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Clonidine

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Identification
Molecular formula
C9H9Cl2N3
CAS number
4205-90-7
IUPAC name
N-[(2,6-dichlorophenyl)methyleneamino]-4,5-dihydro-1H-imidazol-2-amine
State
State

At room temperature, Clonidine is in a solid state.

Melting point (Celsius)
173.50
Melting point (Kelvin)
446.65
Boiling point (Celsius)
295.00
Boiling point (Kelvin)
568.15
General information
Molecular weight
230.09g/mol
Molar mass
230.0940g/mol
Density
1.7490g/cm3
Appearence

Clonidine appears as a white to off-white crystalline powder.

Comment on solubility

Solubility of N-[(2,6-dichlorophenyl)methyleneamino]-4,5-dihydro-1H-imidazol-2-amine

The solubility of N-[(2,6-dichlorophenyl)methyleneamino]-4,5-dihydro-1H-imidazol-2-amine can be influenced by various factors, including its chemical structure and the nature of solvents. Understanding its solubility characteristics is crucial for applications in pharmaceuticals, materials science, and chemical synthesis. Here are some key points to consider:

  • Water Solubility: The compound's solubility in water is expected to be relatively low. This is often due to the presence of bulky groups like the 2,6-dichlorophenyl moiety, which may hinder effective interaction with water molecules.
  • Organic Solvents: It may exhibit better solubility in organic solvents such as dimethyl sulfoxide (DMSO) or dimethylformamide (DMF), which can better accommodate its non-polar characteristics.
  • pH Dependency: The solubility can also vary with pH levels, especially if the compound can ionize. In acidic or basic environments, the solubility might increase due to the formation of soluble ionic species.

Furthermore, as a rule of thumb in chemistry, "like dissolves like." Therefore, understanding the polarity of the solvent compared to the polarity of the compound is essential for predicting solubility. Experimentation and quantitative analysis might be necessary to establish precise solubility values for various solvents.

Research into the solubility behavior of this compound may provide valuable insights for its potential applications and promote optimal conditions for its usage in practical scenarios.

Interesting facts

Interesting Facts about N-[(2,6-dichlorophenyl)methyleneamino]-4,5-dihydro-1H-imidazol-2-amine

N-[(2,6-dichlorophenyl)methyleneamino]-4,5-dihydro-1H-imidazol-2-amine is a fascinating compound that exhibits some noteworthy characteristics and potential applications:

  • Biological Activity: This compound has been studied for its significant biological activities, including potential anti-cancer properties. Some derivatives have shown promise in inhibiting tumor growth in various cancer models.
  • Pharmaceutical Relevance: The imidazole ring, present in the structure, is a well-known pharmacophore. Compounds with imidazole moieties have been widely utilized in medicinal chemistry due to their effectiveness against a broad range of diseases.
  • Structural Diversity: The presence of the 2,6-dichlorophenyl group allows for varied interactions in biological systems, enhancing its potential as a lead compound for drug development.
  • Synthetic Pathways: The synthesis of this compound can be attained through various methodologies, showcasing its versatility in organic synthesis and its relevance in developing novel chemical entities.
  • Research Opportunities: Scientists continue to explore the modifications of this compound to improve efficacy and reduce side effects, making it a potential subject for ongoing research and development in the field of medicinal chemistry.

As with many compounds in the realm of pharmaceuticals, the journey from basic research to practical application is complex, yet rewarding. The compound's unique structure exemplifies the intricate interplay between organic chemistry and biological activity, paving the way for advancements in medicine.

In laboratory settings, understanding the reactivity and stability of such compounds is crucial for developing new therapeutic strategies that could potentially lead to breakthroughs in treating various diseases. The exploration of this compound embodies the essence of scientific inquiry, where every discovery could significantly impact health and well-being.

Synonyms
orb2944754
SCHEMBL10639113