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Bupropion

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Identification
Molecular formula
C13H18ClNO
CAS number
31677-93-7
IUPAC name
N-[(2,6-dimethoxyphenyl)methyl]-N-ethyl-ethanamine
State
State

Bupropion is generally found in a solid state at room temperature.

Melting point (Celsius)
234.00
Melting point (Kelvin)
507.15
Boiling point (Celsius)
210.00
Boiling point (Kelvin)
483.15
General information
Molecular weight
239.32g/mol
Molar mass
239.3150g/mol
Density
1.0385g/cm3
Appearence

Bupropion appears as a white, crystalline powder. It is practically insoluble in water but freely soluble in organic solvents such as acetone and chloroform, highlighting its lipophilic nature.

Comment on solubility

Solubility of N-[(2,6-dimethoxyphenyl)methyl]-N-ethyl-ethanamine

N-[(2,6-dimethoxyphenyl)methyl]-N-ethyl-ethanamine is a member of the amine class of compounds, and its solubility can vary based on several factors. Understanding its solubility characteristics is important, especially in the context of its practical applications. Here are some key points regarding the solubility of this compound:

  • Polarity: The presence of ether groups in the structure suggests that this compound may exhibit some level of polarity, affecting its solubility in various solvents.
  • Solvent Compatibility: Typically, alkylamines like this compound are more soluble in organic solvents such as ethanol or methanol rather than water due to their hydrophobic ethyl group.
  • Temperature Influence: Solubility can significantly change with temperature. Increased temperatures generally enhance the solubility of organic compounds.
  • pH Effects: Being an amine, the compound may interact with acids or bases, potentially altering its solubility. In acidic conditions, it could become protonated, affecting solubility in water.

In summary, while N-[(2,6-dimethoxyphenyl)methyl]-N-ethyl-ethanamine is expected to have limited solubility in polar protic solvents such as water, it is anticipated to be more soluble in non-polar or slightly polar organic solvents due to its overall molecular structure. Experimentation will provide further insights into its solubility behavior.

Interesting facts

Interesting Facts about N-[(2,6-dimethoxyphenyl)methyl]-N-ethyl-ethanamine

This intriguing compound, N-[(2,6-dimethoxyphenyl)methyl]-N-ethyl-ethanamine, belongs to the family of substituted amines and has been the focus of various studies in the realm of medicinal chemistry due to its potential pharmacological properties.

Pharmacological Significance

The unique structure of this compound, characterized by the presence of a dimethoxyphenyl group, may influence its interaction with biological targets. Some interesting aspects include:

  • Potential Antidepressant Activity: Certain substituted amines have shown efficacy in modulating neurotransmitter systems, suggesting that this compound may be studied for its possible antidepressant effects.
  • Influence on Receptors: This compound may interact with various receptors in the brain, which has implications for neurological health and treatment of various mental health disorders.
  • Synthetic Versatility: The synthesis of such compounds can often be achieved through diverse methods, making them interesting subjects for organic chemistry enthusiasts.

Chemical Properties and Research Applications

The properties of N-[(2,6-dimethoxyphenyl)methyl]-N-ethyl-ethanamine open avenues for significant research, especially in:

  • Drug Development: The modification of this compound can lead to novel analogs with enhanced therapeutic profiles.
  • Structure-Activity Relationships: Analyzing how variations in the chemical structure affect biological activity can provide insights into the design of better pharmaceuticals.
  • Diverse Applications: Beyond medicinal chemistry, the compound may find applications in areas such as agrochemicals and materials science.

As scientists continue to investigate compounds like N-[(2,6-dimethoxyphenyl)methyl]-N-ethyl-ethanamine, they unlock new potentials in creating effective therapeutics and deepening our understanding of complex biochemical systems. As noted by chemists: "Every compound has a story to tell—it's our job to listen."