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Propofol

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Identification
Molecular formula
C12H18O
CAS number
2078-54-8
IUPAC name
N-(2,6-dimethyl-4-phenoxy-phenyl)-2-(dipropylamino)acetamide
State
State

Propofol is a liquid at room temperature, often appearing as a white, milky, oil-in-water emulsion when formulated for medical use.

Melting point (Celsius)
18.00
Melting point (Kelvin)
291.15
Boiling point (Celsius)
352.40
Boiling point (Kelvin)
625.55
General information
Molecular weight
178.27g/mol
Molar mass
178.2710g/mol
Density
1.0930g/cm3
Appearence

Propofol is an oil that is typically a white liquid when prepared for medical use. It is often sold in a milky white emulsion form due to being insoluble in water, with the oil droplets being suspended in an aqueous phase. It is characterized by its smooth texture and is usually odorless.

Comment on solubility

Solubility of N-(2,6-dimethyl-4-phenoxy-phenyl)-2-(dipropylamino)acetamide

N-(2,6-dimethyl-4-phenoxy-phenyl)-2-(dipropylamino)acetamide, with its complex structure, presents a unique profile when it comes to solubility. Understanding the solubility properties of this compound is essential for predicting its behavior in different environments and applications.

Factors Influencing Solubility

The solubility of this compound can be influenced by several factors:

  • Polarity: Given the presence of both a polar amine group and a less polar aromatic system, the compound may exhibit varying solubility in polar vs. non-polar solvents.
  • Hydrogen Bonding: The ability of dipropylamino groups to engage in hydrogen bonding can increase solubility in aqueous environments.
  • Temperature: As with many chemical compounds, increasing temperature often enhances solubility in solvents.

Solubility Characteristics

In general, one might observe the following characteristics regarding the solubility of N-(2,6-dimethyl-4-phenoxy-phenyl)-2-(dipropylamino)acetamide:

  • It may be more soluble in organic solvents such as ethanol or dimethyl sulfoxide (DMSO).
  • Its aqueous solubility could be limited but may improve in specific pH conditions due to ionization of the amine group.
  • Interactions with other solutes or solvents can create opportunities for enhanced solubility through complex formation.

Ultimately, the solubility of N-(2,6-dimethyl-4-phenoxy-phenyl)-2-(dipropylamino)acetamide is a compound of interest, meriting further exploration in diverse chemical mediums.

Interesting facts

Interesting Facts about N-(2,6-dimethyl-4-phenoxy-phenyl)-2-(dipropylamino)acetamide

N-(2,6-dimethyl-4-phenoxy-phenyl)-2-(dipropylamino)acetamide is a fascinating compound, which is often studied for its biological and pharmacological properties. Below are some intriguing aspects of this compound:

  • Complex Structure: This compound exhibits a complex molecular structure that incorporates both a dipropylamino and a phenoxy group. Such structural features are often linked to enhanced biochemical interactions.
  • Potential Pharmacological Activity: Many compounds in its class have been researched for their role in modulation of neurotransmitter pathways, hinting at possible applications in treating neurological disorders.
  • Synthesis Challenges: The synthesis of this compound may involve intricate multi-step processes. Each step requires precise conditions to ensure optimal yield and purity, making it a subject of interest in synthetic organic chemistry.
  • Research Applications: Compounds with this kind of structure are often used in drug discovery programs, leading to a deeper understanding of molecular interactions.
  • Interdisciplinary Relevance: Beyond organic chemistry, this compound also intersects with medicinal chemistry and pharmacology, highlighting the importance of collaborative research across fields.

Additionally, as a student of chemistry, one could appreciate the synthesis and characterization techniques that are essential for understanding compounds like this. As the field of chemistry continually evolves, the potential for novel discoveries based on compounds with such intricate structures keeps the pursuit of knowledge vibrant and exciting.

As scientists delve deeper into the properties and functionalities of this compound, they often recall the words of renowned chemist Robert H. Grubbs: "The beauty of chemistry is in its complexity and unpredictability." This statement resonates well with the exploration of compounds like N-(2,6-dimethyl-4-phenoxy-phenyl)-2-(dipropylamino)acetamide.

Synonyms
17060-64-9
N-(2,6-Dimethyl-4-phenoxyphenyl)-2-(dipropylamino)acetamide
A 1115
2-(Dipropylamino)-4'-phenoxy-2',6'-acetoxylidide
ACETAMIDE, N-(2,6-DIMETHYL-4-PHENOXYPHENYL)-2-(DIPROPYLAMINO)-
DTXSID20168898
2',6'-Acetoxylidide, 2-(dipropylamino)-4'-phenoxy-
DTXCID7091389
2',6'-Acetoxylidide, 2-(dipropylamino)-4'-phenoxy-(8CI)
N-[2,6-DIMETHYL-4-(PHENOXY)PHENYL]-2-(DIPROPYLAMINO)ACETAMIDE