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Ropivacaine

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Identification
Molecular formula
C17H26N2O
CAS number
84057-95-4
IUPAC name
N-(2,6-dimethylphenyl)-1-methyl-piperidine-2-carboxamide
State
State

Ropivacaine is a solid at room temperature.

Melting point (Celsius)
156.00
Melting point (Kelvin)
429.15
Boiling point (Celsius)
413.80
Boiling point (Kelvin)
686.95
General information
Molecular weight
274.41g/mol
Molar mass
274.4120g/mol
Density
1.0120g/cm3
Appearence

Ropivacaine is typically a white crystalline powder.

Comment on solubility

Solubility of N-(2,6-dimethylphenyl)-1-methyl-piperidine-2-carboxamide (C17H26N2O)

The solubility of N-(2,6-dimethylphenyl)-1-methyl-piperidine-2-carboxamide is an intriguing topic, particularly due to its unique chemical structure. This compound exhibits particular interactions with solvents that can significantly influence its solubility properties.

Key Points of Solubility

  • Polar vs. Non-polar: The presence of the amide functional group contributes to the polar characteristics of the molecule, enhancing its solubility in polar solvents like water.
  • Hydrophobic Regions: The bulky dimethylphenyl group and the piperidine ring create hydrophobic regions, suggesting lower solubility in non-polar solvents.
  • Temperature Effects: Increased temperature typically enhances solubility for many compounds, including this one, due to greater molecular motion overcoming intermolecular forces.
  • pH Dependency: The solubility may also vary with pH; for instance, in highly acidic or basic environments, the ionization of the amide group can affect solubility.

Furthermore, it is common to observe that “like dissolves like,” meaning that similar polarity between solute and solvent generally leads to better solubility. Thus, experimenting with various organic solvents may yield interesting results in determining the solubility behavior of this compound.

In summary, N-(2,6-dimethylphenyl)-1-methyl-piperidine-2-carboxamide's solubility is influenced by a combination of polar and non-polar properties, temperature, pH, and the solvent used. An understanding of these factors is crucial for applications in various chemical processes.

Interesting facts

Interesting Facts about N-(2,6-Dimethylphenyl)-1-methyl-piperidine-2-carboxamide

N-(2,6-dimethylphenyl)-1-methyl-piperidine-2-carboxamide is a fascinating compound with numerous implications in both medicinal and chemical research. Below are some intriguing aspects of this compound:

  • Pharmacological Interest: This compound has garnered attention in drug development due to its potential pharmacological properties, which may include analgesic and anti-inflammatory effects.
  • Structural Complexity: The presence of both a piperidine ring and an amide group in its structure enhances its biological activity, making it a valuable target for synthetic chemists.
  • Substituent Influence: The 2,6-dimethylphenyl group attached to the piperidine ring can dramatically influence the compound's biological properties, including receptor affinity and overall efficacy.
  • Synthesis Challenge: The synthesis of this compound may require advanced organic chemistry techniques due to the complex structure and the need for selective substitutions throughout the synthesis steps.
  • Research Applications: It could be utilized in the synthesis of other more complex molecules, thereby serving as a precursor in the design of new therapeutic agents.

As a chemistry student or a scientist, understanding the implications and potentials of compounds like N-(2,6-dimethylphenyl)-1-methyl-piperidine-2-carboxamide opens up pathways for innovative drug discovery and development. The ongoing research into its derivatives may lead to the formulation of more effective medical treatments.

In the words of a famous chemist, "Science knows no country, because knowledge belongs to humanity, and is the torch which illuminates the world." This highlights the integral role that compounds like this one play in expanding our collective understanding and innovation in the field of pharmaceuticals.

Synonyms
mepivacaine
96-88-8
N-(2,6-Dimethylphenyl)-1-methylpiperidine-2-carboxamide
DL-Mepivacaine
Carbocaine
Scandicaine
Mepivacaina
Mepicaine
Mepivacainum
22801-44-1
tevacaine
Mepivicaine
Polocaine
Mepivacainum [INN-Latin]
Mepivacaina [INN-Spanish]
Carboplyin Dental
2-Piperidinecarboxamide, N-(2,6-dimethylphenyl)-1-methyl-
(+-)-1-Methyl-2',6'-pipecoloxylidide
1-METHYL-2',6'-PIPECOLOXYLIDIDE
2',6'-Pipecoloxylidide, 1-methyl-
Mepisv
N-(2,6-Dimethylphenyl)-1-methyl-2-piperidinecarboxamide
N-Methyl-2-pipecolic acid, 2,6-xylidide
(+/-)-Mepivacaine
CHEBI:6759
N-Methyl-2-pipecolic acid, 2,6-dimethylanilide
EINECS 202-543-0
UNII-B6E06QE59J
N-Methylhexahydro-2-picolinic acid, 2,6-dimethylanilide
Mepivacaine (INN)
B6E06QE59J
APF-135
DTXSID9023259
Mepihexal
Scandicane
S-Ropivacaine Mesylate
MEPIVACAINE [INN]
Mepivacainum (INN-Latin)
Mepivacaina (INN-Spanish)
BRN 0211230
Mepivacaine [INN:BAN]
2-PIPERIDINECARBOXAMIDE, N-(2,6-DIMETHYLPHENYL)-1-METHYL-, (+/-)-
Carboplyin Dental (TN)
5-22-01-00223 (Beilstein Handbook Reference)
MFCD00243006
Mepivacaine (Standard)
Spectrum_001480
SpecPlus_000874
MEPIVACAINE [MI]
Spectrum2_001656
Spectrum3_001629
Spectrum4_000596
Spectrum5_001354
(.+/-.)-Mepivacaine
Epitope ID:122686
MEPIVACAINE [VANDF]
CHEMBL1087
SCHEMBL25314
BSPBio_003297
KBioGR_001092
KBioSS_001960
MEPIVACAINE [WHO-DD]
MLS006011662
DivK1c_006970
SPBio_001811
DTXCID803259
GTPL7224
HY-B0517R
KBio1_001914
KBio2_001960
KBio2_004528
KBio2_007096
KBio3_002517
Mepivacaine, 1mg/ml in Methanol
N01BB03
HMS3886E04
HY-B0517
BDBM50417964
s5392
AKOS015889304
AC-9857
CCG-266926
DB00961
FS-3679
NCGC00018284-02
NCGC00018284-03
NCGC00018284-05
NCGC00018284-06
NCGC00089774-02
FM142923
SMR004703413
SBI-0052814.P002
DB-343491
CS-0009492
NS00000534
(.+/-.)-1-Methyl-2',6'-pipecoloxylidide
C07528
D08181
AB00053769_12
AB00053769_13
EN300-7359348
(+/-)-1-METHYL-2',6'-PIPECOLOXYLIDIDE
Q416760
BRD-A03216249-003-02-9
BRD-A03216249-003-12-8
BRD-A03216249-003-23-5
BRD-A03216249-003-24-3
Z1741980843
N-(2,6-Dimethylphenyl)-1-methyl-2-piperidinecarboxamide #
N-(2,6-dimethylphenyl)-1-methylpiperidine-2-carboximidic acid
N- (2, 6- Dimethylphenyl) - 1- methylpiperidine- 2- carboxamide
N-(2 pound not6-Dimethylphenyl)-1-methylpiperidine-2-carboxamide
202-543-0