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Lidocaine

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Identification
Molecular formula
C14H22N2O2
CAS number
137-58-6
IUPAC name
N-(2,6-dimethylphenyl)-2-(2-methoxyethylamino)acetamide
State
State

At room temperature, lidocaine is typically in a solid state as a white crystalline powder. However, it is also available in liquid form for solutions and topical applications.

Melting point (Celsius)
66.00
Melting point (Kelvin)
339.15
Boiling point (Celsius)
350.00
Boiling point (Kelvin)
623.15
General information
Molecular weight
234.34g/mol
Molar mass
234.3380g/mol
Density
1.0260g/cm3
Appearence

Lidocaine appears as a white to off-white crystalline powder. It is odorless and has a slightly bitter taste. The compound is often used in various forms such as gels, creams, and aqueous solutions for topical application, and it dissolves readily in water, alcohol, and other organic solvents.

Comment on solubility

Solubility of N-(2,6-dimethylphenyl)-2-(2-methoxyethylamino)acetamide

When evaluating the solubility of the compound N-(2,6-dimethylphenyl)-2-(2-methoxyethylamino)acetamide, it is essential to consider several factors that influence its ability to dissolve in various solvents. The following points highlight key aspects of its solubility:

  • Polarity: The presence of both hydrophobic aromatic rings and hydrophilic amino groups suggests that the compound has both polar and non-polar characteristics, which may facilitate solubility in a range of solvents.
  • Solvent Compatibility: This compound is expected to be more soluble in polar organic solvents such as methanol, ethanol, and possibly DMSO, while showing limited solubility in non-polar solvents like hexane.
  • Temperature Effects: Temperature may also play a significant role in enhancing solubility, as higher temperatures generally increase molecular movement, thus aiding dissolution.
  • Influence of pH: The solubility may be affected by the pH of the solution, especially due to the presence of the amino group, which can protonate, leading to increased solubility in acidic conditions.

In summary, while the solubility of N-(2,6-dimethylphenyl)-2-(2-methoxyethylamino)acetamide can be anticipated to vary based on solvent choice and environmental conditions, its unique structure allows for interactions within both polar and non-polar mediums. Understanding these solubility characteristics is crucial for applications in pharmaceuticals and chemical formulations.

Interesting facts

Interesting Facts about N-(2,6-Dimethylphenyl)-2-(2-methoxyethylamino)acetamide

N-(2,6-dimethylphenyl)-2-(2-methoxyethylamino)acetamide is a fascinating compound, primarily studied for its potential applications in pharmaceuticals. This compound is part of the broader family of amides, which are known for their diverse biological activities. Here are some intriguing aspects of this compound:

  • Pharmaceutical Potential: Compounds like this one are often evaluated for their ability to act as enzyme inhibitors, which can play a critical role in various therapeutic treatments.
  • Structural Variety: The presence of both a dimethylphenyl group and a methoxyethylamino group in its structure highlights the chemical diversity that can lead to novel properties and activities.
  • Amide Bond: The amide functional group is pivotal in medicinal chemistry, often influencing the pharmacokinetics and pharmacodynamics of drugs.
  • Targeting Specific Pathways: Researchers are keen to explore how modifications to the basic structure can optimize the compound's affinity for specific biological targets, potentially leading to new treatment options.
  • Research Trends: This compound exemplifies a trend in modern chemistry, where the systematic alteration of molecular structure is paramount in discovering highly effective pharmaceuticals.

In conclusion, N-(2,6-dimethylphenyl)-2-(2-methoxyethylamino)acetamide serves as a compelling example of how subtle changes in molecular architecture can drive the discovery of new and effective therapeutics. The ongoing research into compounds like this could unveil important advancements in medicinal science.

Synonyms
BRN 2980521
2-(2-Methoxyethylamino)-2',6'-dimethylacetanilide
2',6'-ACETOXYLIDIDE, 2-((2-METHOXYETHYL)AMINO)-
22151-64-0
DTXSID90176682
RefChem:241067
DTXCID3099173
AKOS005321741