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Lidocaine

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Identification
Molecular formula
C14H22N2O
CAS number
137-58-6
IUPAC name
N-(2,6-dimethylphenyl)-2-(3-methoxypropylamino)acetamide
State
State

At room temperature, lidocaine is typically a solid. It can be found in a crystalline form, often prepared as a powder. In some pharmaceutical preparations, lidocaine is dissolved in a liquid solution to facilitate topical or injectable administration.

Melting point (Celsius)
66.00
Melting point (Kelvin)
339.15
Boiling point (Celsius)
350.00
Boiling point (Kelvin)
623.15
General information
Molecular weight
234.34g/mol
Molar mass
234.3420g/mol
Density
1.0260g/cm3
Appearence

Lidocaine is a white solid, crystalline substance. It is typically found in powder form and is odorless. In some formulations, it may appear as a liquid if in solution. Its crystalline structure and white coloration are typical of many organic solids used in pharmacological applications.

Comment on solubility

Solubility of N-(2,6-dimethylphenyl)-2-(3-methoxypropylamino)acetamide

N-(2,6-dimethylphenyl)-2-(3-methoxypropylamino)acetamide exhibits interesting solubility properties that can be quite significant in various chemical applications. Generally, this compound is expected to demonstrate solubility in organic solvents but limited solubility in water. The solubility characteristics can be influenced by several key factors:

  • Polarity: Due to the presence of a polar amine group, the compound may engage in hydrogen bonding, affecting its solubility.
  • Hydrophobic Groups: The dimethylphenyl group contributes to hydrophobicity, which can decrease water solubility, while the methoxypropyl group may enhance solubility in certain organic solvents.
  • Temperature: As with many organic compounds, an increase in temperature generally enhances solubility.

In conclusion, the solubility of N-(2,6-dimethylphenyl)-2-(3-methoxypropylamino)acetamide is influenced by its molecular structure and the nature of the solvent used. It often shows higher solubility in organic solvents compared to aqueous solutions. Understanding these solubility parameters is crucial for optimizing its use in experimental settings.

Interesting facts

Interesting Facts about N-(2,6-dimethylphenyl)-2-(3-methoxypropylamino)acetamide

N-(2,6-dimethylphenyl)-2-(3-methoxypropylamino)acetamide is a fascinating compound that showcases the complexity and creativity found in the field of organic chemistry. Here are some compelling points about this compound:

  • Structure and Functionality: This compound belongs to a class of molecules that integrate both aromatic and aliphatic amine functionalities, which can lead to interesting pharmacological properties and potential applications in medicinal chemistry.
  • Binding Potential: Compounds like N-(2,6-dimethylphenyl)-2-(3-methoxypropylamino)acetamide often exhibit unique binding interactions with biological targets, making them candidates for investigating drug-receptor interactions.
  • Synthesis Pathways: The synthesis of this molecule often employs strategies like amide formation or reductive amination, highlighting the versatility of synthetic methodology in organic chemistry.
  • Application in Research: Scientists commonly explore compounds with such structures for their potential roles in drug development, particularly in the fields of analgesics or neuroactive agents due to their possible central nervous system effects.
  • Structurally Related Compounds: One might be intrigued to study similar compounds, as subtle changes in the aromatic or aliphatic groups can significantly alter the pharmacological profile, a common theme in structure-activity relationship (SAR) studies.

In summary, N-(2,6-dimethylphenyl)-2-(3-methoxypropylamino)acetamide stands out not just for its chemical properties but also for the potential implications it holds in scientific research, particularly in drug discovery and development. As a chemical student or researcher, understanding the full scope of such compounds can be the key to unlocking new therapeutic pathways.

Synonyms
BRN 2981314
2-(3-Methoxypropylamino)-2',6'-dimethylacetanilide
2',6'-ACETOXYLIDIDE, 2-((3-METHOXYPROPYL)AMINO)-
22151-65-1
DTXSID50176683
RefChem:241068
DTXCID8099174