Skip to main content

Lidocaine

ADVERTISEMENT
Identification
Molecular formula
C14H22N2O
CAS number
137-58-6
IUPAC name
N-(2,6-dimethylphenyl)-2-phenyl-N-(2-pyrrolidin-1-ylethyl)acetamide
State
State

At room temperature, lidocaine is typically found in solid form as its hydrochloride salt for medical applications. The base form is a crystalline solid.

Melting point (Celsius)
66.00
Melting point (Kelvin)
339.15
Boiling point (Celsius)
350.80
Boiling point (Kelvin)
623.95
General information
Molecular weight
234.34g/mol
Molar mass
234.3420g/mol
Density
1.0260g/cm3
Appearence

Lidocaine appears as a white crystalline powder. It is often odorless or may have a slight characteristic odor.

Comment on solubility

Solubility of N-(2,6-dimethylphenyl)-2-phenyl-N-(2-pyrrolidin-1-ylethyl)acetamide

The solubility of N-(2,6-dimethylphenyl)-2-phenyl-N-(2-pyrrolidin-1-ylethyl)acetamide can provide valuable insights into its potential applications and behavior in various environments. This compound contains both hydrophobic and hydrophilic components, which can influence its solubility in different solvents.

Key Factors Affecting Solubility:

  • Polar and Nonpolar Interactions: The presence of aromatic rings suggests that the compound may exhibit limited solubility in polar solvents, while it could be more soluble in nonpolar or less polar organic solvents.
  • Temperature: Solubility can vary significantly with temperature; typically, higher temperatures increase solubility for many organic compounds.
  • pH Levels: If the compound has any ionizable groups, shifts in pH can also affect solubility, making it more soluble at certain pH levels.

In practical applications, the solubility of a compound is crucial; quotes from literature often emphasize that “the solubility of a drug directly impacts its bioavailability.” This highlights the importance of understanding how N-(2,6-dimethylphenyl)-2-phenyl-N-(2-pyrrolidin-1-ylethyl)acetamide interacts within various chemical environments and its potential effectiveness in formulations.

In summary, while definitive solubility data for this specific compound may not be readily available, its structural properties suggest an intriguing balance of solubility characteristics that warrant further investigation.

Interesting facts

Interesting Facts About N-(2,6-dimethylphenyl)-2-phenyl-N-(2-pyrrolidin-1-ylethyl)acetamide

N-(2,6-dimethylphenyl)-2-phenyl-N-(2-pyrrolidin-1-ylethyl)acetamide is a fascinating compound in the realm of organic chemistry, primarily due to its structural complexity and potential applications. Here are some engaging insights:

  • Structural Diversity: The compound derives its uniqueness from the combination of a dimethylphenyl and pyrrolidine moiety, which contributes to its intricate 3D conformation, influencing its chemical reactivity and interaction with biological systems.
  • Pharmaceutical Potential: This compound has gained attention in medicinal chemistry as an analog that may offer therapeutic benefits in treating certain neurological conditions due to its potential modulatory effects on receptors in the brain.
  • Analogous Compounds: Research in this area often involves synthesis and exploration of variations of such compounds, leading to a better understanding of structure-activity relationships. This compound serves as a basis for generating new analogs that might exhibit enhanced efficacy.
  • Synthetic Challenges: The multi-step synthesis of this compound can present challenges, often requiring careful selection of reagents and reaction conditions to ensure the desired purity and yield.
  • Research Studies: Various studies have investigated the compound's interactions at molecular levels, contributing to a deeper understanding of complex biological pathways. Such research is vital for the ongoing development of targeted drug therapies.

A quote that encapsulates the essence of studying compounds like N-(2,6-dimethylphenyl)-2-phenyl-N-(2-pyrrolidin-1-ylethyl)acetamide is: "Chemistry is the art of problem-solving, and each compound is a puzzle waiting to be solved."

In conclusion, the study of N-(2,6-dimethylphenyl)-2-phenyl-N-(2-pyrrolidin-1-ylethyl)acetamide exemplifies the intersection of creativity and science, offering numerous avenues for exploration and discovery in modern chemistry.

Synonyms
SA 35
18109-53-0
BRN 2778408
ACETANILIDE, 2',6'-DIMETHYL-2-PHENYL-N-(2-(1-PYRROLIDINYL)ETHYL)-
2',6'-Dimethyl-2-phenyl-N-(2-(1-pyrrolidinyl)ethyl)acetanilide
DTXSID50171072
DTXCID9093563
N-(2,6-dimethylphenyl)-2-phenyl-N-(2-pyrrolidin-1-ylethyl)acetamide
SCHEMBL29394125