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Lidocaine

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Identification
Molecular formula
C14H22N2O
CAS number
137-58-6
IUPAC name
N-(2,6-dimethylphenyl)-2-pyrrolidin-1-yl-acetamide
State
State
Lidocaine is typically in a solid state at room temperature, appearing as a white crystalline powder.
Melting point (Celsius)
68.50
Melting point (Kelvin)
341.70
Boiling point (Celsius)
350.80
Boiling point (Kelvin)
624.00
General information
Molecular weight
234.34g/mol
Molar mass
234.3370g/mol
Density
1.0260g/cm3
Appearence

Lidocaine appears as a white, crystalline powder. It is odorless and has a slightly bitter taste. The compound is soluble in water and alcohol, giving clear solutions. In its pure form, lidocaine is often used in pharmaceutical formulations for its anesthetic properties.

Comment on solubility

Solubility of N-(2,6-dimethylphenyl)-2-pyrrolidin-1-yl-acetamide

N-(2,6-dimethylphenyl)-2-pyrrolidin-1-yl-acetamide is a compound that exhibits varying solubility characteristics based on its chemical structure. Understanding its solubility can provide insights into its potential applications and interactions in different environments.

Key Factors Affecting Solubility:

  • Polarity: The presence of polar functional groups in the compound can enhance its solubility in polar solvents such as water.
  • Hydrophobic Regions: The bulky hydrophobic 2,6-dimethylphenyl group may decrease solubility in polar solvents but increase solubility in non-polar solvents.
  • Temperature: Generally, solubility may increase with temperature, although this is not a universal rule.
  • Salt Formation: If the compound can form salts with acids or bases, it may greatly improve its solubility in aqueous solutions.

As a general observation, it is noted that:

  • The solubility of organic compounds like N-(2,6-dimethylphenyl)-2-pyrrolidin-1-yl-acetamide tends to be higher in organic solvents such as ethanol, acetone, or dichloromethane.
  • In contrast, it may be poorly soluble in water due to its hydrophobic character.

Exploring the solubility of this compound not only helps in understanding its behavior in various media but also in optimizing formulations and enhancing bioavailability in medicinal applications.

Interesting facts

Interesting Facts about N-(2,6-dimethylphenyl)-2-pyrrolidin-1-yl-acetamide

N-(2,6-dimethylphenyl)-2-pyrrolidin-1-yl-acetamide is a compound that belongs to the class of amides and holds significance in various fields, particularly in medicinal chemistry. Here are some fascinating aspects:

  • Pharmacological Potential: This compound has been studied for its potential biological activities. It may act as a key player in the development of new therapeutic agents, possibly offering solutions for conditions that require modulation of neurotransmitter activities.
  • Structural Attributes: The presence of a pyrrolidine ring in its structure enhances the compound's ability to interact with biological systems. Such cyclic structures often contribute to improved stability and biological efficacy.
  • Synthesis and Applications: Organic chemists are interested in the synthetic pathways to obtain such compounds. The design and synthesis of derivatives often lead to exploration in pharmaceutical applications, especially in pain management and neurology.
  • Multifaceted Uses: Beyond its potential in medicine, compounds with similar structures are explored for roles in agriculture and material science, showcasing their versatility.
  • Research Insights: Studies have suggested that the interactions of compounds similar to N-(2,6-dimethylphenyl)-2-pyrrolidin-1-yl-acetamide with various receptors can be profound, making it a subject of ongoing research.

In missions aimed at discovering novel therapeutic agents, N-(2,6-dimethylphenyl)-2-pyrrolidin-1-yl-acetamide represents a promising avenue of exploration, bridging the gap between synthetic chemistry and pharmacological applications. As the scientific community delves deeper into its properties and potential uses, we may unlock new frontiers in health and science.

Synonyms
Pyrrocaine
2210-77-7
Pirrocaina
EN-1010
NSC-52644
N-(2,6-dimethylphenyl)-2-pyrrolidin-1-ylacetamide
9D47L94CPW
DTXSID9046150
1-Pyrrolidineacetamide, N-(2,6-dimethylphenyl)-
1-Pyrrolidineaceto-2',6'-xylidide
NCGC00160439-01
DTXCID7026150
Endocaine
SMR000591010
CAS-2210-77-7
Pyrrocainum
Dynacaine
PYRROCAINE [MI]
PYRROCAINE [INN]
Pyrrocaine (USAN/INN)
PYRROCAINE [USAN]
Pyrrocainum [INN-Latin]
Pirrocaina [INN-Spanish]
PYRROCAINE [WHO-DD]
UNII-9D47L94CPW
SCHEMBL25718
MLS000881143
MLS000881194
Pyrrocaine [USAN:INN:BAN]
N-(2,6-Dimethylphenyl)-2-(1-pyrrolidinyl)acetamide
CHEMBL1895219
CHEBI:134946
OYCGKECKIVYHTN-UHFFFAOYSA-N
HMS2914E08
1-Pyrrolidinoaceto-2',6'-xylidide
Tox21_111811
NSC 52644
STK409086
AKOS003974196
Tox21_111811_1
NCGC00160439-02
1-PYRROLIDINEACETO-2',6'-XYLIDIDE.
D05665
F96615
N-(2,6-Dimethylphenyl)-1-pyrrolidineacetamide
SR-01000031189
SR-01000031189-1
N-(2,6-dimethylphenyl)-2-(pyrrolidin-1-yl)acetamide
Q27272378
Z46169098