Skip to main content

Lidocaine

ADVERTISEMENT
Identification
Molecular formula
C14H22N2O
CAS number
137-58-6
IUPAC name
N-(2,6-dimethylphenyl)-N-(2-morpholinoethyl)-2-phenyl-acetamide
State
State

At room temperature, Lidocaine is typically in a crystalline solid state. It is stable under normal conditions but should be stored in a dry place, away from excessive moisture and direct sunlight to maintain its efficacy and shelf life.

Melting point (Celsius)
68.00
Melting point (Kelvin)
341.15
Boiling point (Celsius)
180.00
Boiling point (Kelvin)
453.15
General information
Molecular weight
234.34g/mol
Molar mass
234.3370g/mol
Density
1.0260g/cm3
Appearence

Lidocaine appears as a white crystalline solid. It is commonly in the form of powder or crystals that are practically odorless. Its crystalline nature makes it suitable for precise pharmaceutical dosing.

Comment on solubility

Solubility of N-(2,6-dimethylphenyl)-N-(2-morpholinoethyl)-2-phenyl-acetamide

The solubility of N-(2,6-dimethylphenyl)-N-(2-morpholinoethyl)-2-phenyl-acetamide in various solvents is a crucial aspect for both its practical applications and research purposes. Understanding its solubility characteristics can help in determining its behavior in different environments. Here are some key points to consider:

  • Polarity: Given the presence of both aromatic and amine functional groups, this compound exhibits **moderate polarity**. This means it may have varying levels of solubility in polar and non-polar solvents.
  • Solvent Compatibility: The solubility can be described in a few categories:
    • Highly soluble: It may dissolve well in organic solvents such as dimethyl sulfoxide (DMSO), acetone, or ethanol.
    • Moderately soluble: It may possess some solubility in less polar solvents like ethyl acetate.
    • Poor solubility: In highly polar solvents, especially water, it may show poor solubility due to the hydrophobic nature of its aromatic components.
  • Temperature Effects: Solubility may also vary with temperature. Typically, an increase in temperature can enhance solubility, particularly in organic solvents.
  • pH Influence: As a compound containing amine groups, its solubility can be affected by the pH of the environment, where it may become more soluble in acidic conditions due to protonation.

Ultimately, the solubility of this compound is essential for its application in pharmaceutical formulations and research settings, where the solubility profile can influence bioavailability and the mode of use.

Interesting facts

Interesting Facts about N-(2,6-dimethylphenyl)-N-(2-morpholinoethyl)-2-phenyl-acetamide

N-(2,6-dimethylphenyl)-N-(2-morpholinoethyl)-2-phenyl-acetamide, commonly referred to as a member of the acetamide family, exhibits some fascinating characteristics that make it a subject of interest in the realm of chemistry.

Chemical Structure and Properties

This compound features a complex structure with multiple aromatic rings and functional groups, which can lead to intriguing interactions with biological systems. Here are some noteworthy aspects:

  • Diverse Functional Groups: The presence of both morpholino and acetamide groups facilitates various chemical reactions, indicating its potential versatility in synthetic chemistry.
  • Aromatic Dynamics: The 2,6-dimethylphenyl group contributes to the compound's lipophilicity, enhancing its ability to permeate biological membranes.

Applications and Biological Relevance

N-(2,6-dimethylphenyl)-N-(2-morpholinoethyl)-2-phenyl-acetamide has garnered attention for its potential applications, particularly in pharmaceutical chemistry:

  • Pharmaceutical Development: Investigations into the compound's pharmacokinetics and pharmacodynamics might reveal valuable insights into new therapeutic agents.
  • Neurological Research: Due to the morpholino structure, this compound may exhibit interesting effects on nerve function, making it a candidate for further studies in neuropharmacology.

Research and Future Directions

As with many complexes in medicinal chemistry, the exploration of N-(2,6-dimethylphenyl)-N-(2-morpholinoethyl)-2-phenyl-acetamide is still ongoing. Future research may focus on:

  • Mechanistic Studies: Understanding how this compound interacts with particular biological targets can reveal its mode of action.
  • Derivative Exploration: Synthesizing derivatives with modifications to the molecular structure could yield compounds with enhanced efficacy or reduced side effects.

In summary, N-(2,6-dimethylphenyl)-N-(2-morpholinoethyl)-2-phenyl-acetamide is a compound rich in potential, serving as a valuable tool for chemists and researchers aiming to uncover novel applications in medicine and beyond. Its intricate structure and diverse functionalities offer an exciting avenue for discovery!

Synonyms
18109-48-3
SA 33
Acetanilide, 2',6'-dimethyl-N-(2-morpholinoethyl)-2-phenyl-
BRN 1172353
2',6'-Dimethyl-N-(2-morpholinoethyl)-2-phenylacetanilide
DTXSID30171070
DTXCID9093561
N-(2,6-dimethylphenyl)-N-(2-morpholin-4-ylethyl)-2-phenylacetamide
SCHEMBL29392976