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Pseudoephedrine sulfate

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Identification
Molecular formula
C11H17NO2S⋅H4NO3S
CAS number
57576-62-2
IUPAC name
N-[3-[1-hydroxy-2-(methylamino)ethyl]phenyl]methanesulfonamide;methanesulfonic acid
State
State

At room temperature, the compound is typically a solid.

Melting point (Celsius)
47.00
Melting point (Kelvin)
320.15
Boiling point (Celsius)
218.00
Boiling point (Kelvin)
491.15
General information
Molecular weight
428.59g/mol
Molar mass
428.5860g/mol
Density
1.2900g/cm3
Appearence

This compound generally appears as a white crystalline powder or crystals.

Comment on solubility

Solubility of N-[3-[1-hydroxy-2-(methylamino)ethyl]phenyl]methanesulfonamide; methanesulfonic acid

The solubility of N-[3-[1-hydroxy-2-(methylamino)ethyl]phenyl]methanesulfonamide; methanesulfonic acid can be understood through several key factors:

  • Solvent Interaction: This compound displays considerable solubility in polar solvents such as water due to the presence of polar functional groups, particularly the hydroxyl and sulfonamide moieties.
  • pH Influence: The solubility may be affected by the pH of the solution. At varying pH levels, the ionization of the amine groups may lead to increased solubility.
  • Temperature Dependency: Like many organic compounds, the solubility can also be temperature-dependent; higher temperatures typically increase the solubility of solid solutes.
  • Concentration Effects: In concentrated solutions, there may be a limit to solubility due to precipitation, which can affect pharmacological behavior.

It is also worth noting that, as with many sulfonamides, solubility is crucial in determining the bioavailability and therapeutic efficacy of the compound. In summary, while N-[3-[1-hydroxy-2-(methylamino)ethyl]phenyl]methanesulfonamide; methanesulfonic acid is generally soluble in polar solvents, its solubility characteristics are influenced by temperature, pH levels, and the surrounding chemical environment.

Interesting facts

Exploring N-[3-[1-hydroxy-2-(methylamino)ethyl]phenyl]methanesulfonamide

N-[3-[1-hydroxy-2-(methylamino)ethyl]phenyl]methanesulfonamide, often referred to simply as its parenteral compound, is a fascinating chemical primarily known for its roles in medicinal chemistry and therapeutic applications.

Key Insights:

  • Structure and Function: This compound displays a unique molecular architecture, which combines the functionalities of a sulfonamide with an amine, leading to significant biological activity.
  • Pharmaceutical Applications: Its application in drug synthesis highlights the compound's effectiveness in treating various medical conditions, particularly those involving the central nervous system.
  • Mechanism of Action: The sulfonamide group in its structure often acts by inhibiting specific enzymes, thereby modulating metabolic reactions. This can be crucial in the development of treatments for diseases like hypertension.
  • Research Interest: Scientists are particularly interested in the compound's interactions at the molecular level, offering insights into drug-receptor binding dynamics and potential for new therapeutic targets.
  • Development History: Historically, sulfonamides were among the first antibiotics discovered, opening the doors for further exploration of related compounds in antiviral and antitumor research.

Moreover, the multifunctionality of N-[3-[1-hydroxy-2-(methylamino)ethyl]phenyl]methanesulfonamide makes it an exciting subject for ongoing research as medicinal chemists strive to optimize its efficacy and reduce side effects. As quoted, "Every molecule has a story; some tell tales of wellness, while others narrate the struggle against diseases."

In summary, N-[3-[1-hydroxy-2-(methylamino)ethyl]phenyl]methanesulfonamide serves as an excellent example of how intricate chemical structures can lead to substantial health advancements, showcasing the intricate link between chemistry and medicine. As research continues to unfold, this compound and its derivatives may shape the future of pharmacological innovations.

Synonyms
AMIDEPHRINE MESYLATE
Fentrinol
1421-68-7
Amidephrine mesylate, (-)-
(-)-Amidefrine mesilate
Amidephrine mesylate [USAN]
UNII-WS98QAM6EB
WS98QAM6EB
amidephrine mesilate
Amidefrine mesilate [INN]
Mesilate d'amidefrine
S3IG39T94B
3'-(1-Hydroxy-2-(methylamino)ethyl)methanesulfonanilide monomethanesulfonate (salt)
87338-94-1
Methanesulfonamide, N-(3-(1-hydroxy-2-(methylamino)ethyl)phenyl)-, (-)-, monomethanesulfonate (salt)
Dricol
Nalde
Amidefrine mesilate (INN)
Amidefrini mesylas
Amidefrine mesylate
Methanesulfonamide, N-(3-(1-hydroxy-2-(methylamino)ethyl)phenyl)-, monomethanesulfonate (salt)
N-[3-[1-hydroxy-2-(methylamino)ethyl]phenyl]methanesulfonamide;methanesulfonic acid
Amidephrine mesylate (USAN)
Mesylate d'amideferine
Amidephrine methanesulfonate
Amidefrini mesilas
Amideferini mesilas
Amidephrine monomethanesulfonate
Amideferini mesilas [INN-Latin]
Amidefrini mesilas [INN-Spanish]
MJ-5190
Mesilate d'amidefrine [INN-French]
MJ 5190
UNII-S3IG39T94B
Amidephrine monoethanesulfonate
(2-Methylamine-1-hydroxyethyl)methanesulfonanilide methanesulfonate
3'-(1-Hydroxy-2-(methylamino)ethyl)methanesulfonanilide methanesulfonate
3'-(2-(Methylamino)-l-hydroxyethyl)methanesulfonanilide methanesulfonate
Methanesulfonanilide, 3'-(1-hydroxy-2-(methylamino)ethyl)-, methanesulfonate
63HPK6A5CW
Methanesulfonamide, N-(3-(1-hydroxy-2-(methylamino)ethyl)phenyl)-, monomethanesulfonate salt
SCHEMBL122478
(+)-AMIDEFRINE MESILATE
DTXSID00931340
AMIDEFRINE MESILATE [MART.]
AMIDEPHRINE MESYLATE, (+)-
3-(2-Methylamino-1-hydroxyethyl)methanesulfonanilide methanesulfonate
AMIDEFRINE MESILATE [WHO-DD]
Methanesulfonanilide, 3'-(1-hydroxy-2-(methylamino)ethyl)-, monomethanesulfonate (salt)
AMIDEPHRINE METHANESULFONATE [MI]
D02901
Methanesulfonic acid--N-{3-[1-hydroxy-2-(methylamino)ethyl]phenyl}methanesulfonamide (1/1)
3'-(1-HYDROXY-2-(METHYLAMINO)ETHYL)METHANESULPHONANILIDE MONOMETHANESULPHONATE (SALT)
METHANESULFONAMIDE, N-(3-(1-HYDROXY-2-(METHYLAMINO)ETHYL)PHENYL)-, (+)-, MONOMETHANESULFONATE (SALT)
METHANESULPHONAMIDE, N-(3-(1-HYDROXY-2-(METHYLAMINO)ETHYL)PHENYL)-, MONOMETHANESULPHONATE (SALT)