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Tacrolimus

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Identification
Molecular formula
C44H69NO12
CAS number
104987-11-3
IUPAC name
N-[3-(11,19-dihydroxy-8,12-dimethyl-2,6-dioxo-3,7-dioxabicyclo[13.4.0]nonadeca-1(15),9,12,16,18-pentaen-4-yl)prop-1-enyl]-4-methoxyimino-but-2-enamide
State
State

At room temperature, tacrolimus is a solid compound. It tends to form crystals and is typically stable under normal environmental conditions.

Melting point (Celsius)
128.00
Melting point (Kelvin)
401.15
Boiling point (Celsius)
235.00
Boiling point (Kelvin)
508.15
General information
Molecular weight
804.02g/mol
Molar mass
804.0190g/mol
Density
1.1300g/cm3
Appearence

Tacrolimus usually appears as a white crystalline powder. It is noted for its moderate solubility in water but is more soluble in various organic solvents. As a compound used in pharmaceuticals, its appearance can sometimes vary slightly depending on the formulation.

Comment on solubility

Solubility of N-[3-(11,19-dihydroxy-8,12-dimethyl-2,6-dioxo-3,7-dioxabicyclo[13.4.0]nonadeca-1(15),9,12,16,18-pentaen-4-yl)prop-1-enyl]-4-methoxyimino-but-2-enamide

The solubility of the compound N-[3-(11,19-dihydroxy-8,12-dimethyl-2,6-dioxo-3,7-dioxabicyclo[13.4.0]nonadeca-1(15),9,12,16,18-pentaen-4-yl)prop-1-enyl]-4-methoxyimino-but-2-enamide (C44H69NO12) is influenced by various factors due to its complex structure. Understanding its solubility characteristics can be essential for applications in pharmacology and material science.

Key points regarding its solubility include:

  • Solvent Compatibility: This compound may display varying solubility in polar and non-polar solvents depending on its functional groups.
  • Hydrogen Bonding: The presence of hydroxy and methoxy groups could enhance solubility in polar solvents due to hydrogen bonding interactions.
  • Hydrophobic Regions: The bulky hydrocarbon portions of the molecule may hinder solubility in highly polar solvents.
  • Temperature Effects: Solubility generally increases with temperature; thus, this property should be considered in practical applications.

In conclusion, while the compound's solubility may not be easily categorized as either high or low, it is expected to demonstrate significant variation depending on the solvent employed. As such, experimentation will be essential to determine optimal conditions for dissolution. Recognizing the nuances of solubility will pave the way for its effective utilization in various fields.

Interesting facts

Interesting Facts about N-[3-(11,19-Dihydroxy-8,12-dimethyl-2,6-dioxo-3,7-dioxabicyclo[13.4.0]nonadeca-1(15),9,12,16,18-pentaen-4-yl)prop-1-enyl]-4-methoxyimino-but-2-enamide

This compound, known for its complex structure and unique properties, offers fascinating insights into the world of organic chemistry. Here are some noteworthy points about this intriguing molecule:

  • Structural Complexity: The compound features a bicyclic structure, which provides distinct geometric and electronic properties. Bicyclic compounds are often studied for their reactivity and stability.
  • Functional Groups: The presence of multiple functional groups, such as hydroxy and methoxy, contributes to its potential applications in pharmaceuticals and materials science.
  • Synthetic Routes: The synthesis of such complex molecules often requires innovative methodologies, including the use of protecting groups and advanced coupling reactions. Chemists thrive on challenges like these!
  • Potential Biological Activity: Compounds with similar structures have been implicated in various biological activities, making them prime candidates for drug discovery studies.
  • Historical Context: The study of analogous bicyclic compounds has led to significant discoveries in the field, including natural products and their derivatives, which have provided invaluable insights into medicinal chemistry.

As one delves deeper into the structure and reactivity of this compound, one can't help but marvel at the beauty and complexity of organic molecules. Its synthesis and potential applications open up questions that drive scientific inquiry, leading to new discoveries that challenge our understanding of chemical interactions.

In the words of a famous chemist, "Chemistry is the art of transformation," and understanding compounds like this one exemplifies that transformative nature!