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Tofisopam

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Identification
Molecular formula
C17H19ClN2O
CAS number
22345-47-7
IUPAC name
N-[[3-(4-chlorophenyl)isoxazol-5-yl]methyl]-N-ethyl-ethanamine
State
State

Tofisopam is typically found in a solid state at room temperature.

Melting point (Celsius)
104.00
Melting point (Kelvin)
377.15
Boiling point (Celsius)
402.15
Boiling point (Kelvin)
675.30
General information
Molecular weight
383.92g/mol
Molar mass
383.9160g/mol
Density
1.2600g/cm3
Appearence

Tofisopam typically appears as a white to off-white crystalline powder.

Comment on solubility

Solubility of N-[[3-(4-chlorophenyl)isoxazol-5-yl]methyl]-N-ethyl-ethanamine

The solubility of N-[[3-(4-chlorophenyl)isoxazol-5-yl]methyl]-N-ethyl-ethanamine can be influenced by various factors, including its molecular structure and the polarity of the solvent used. Generally, the solubility of such compounds can vary significantly in different solvents.

Key Considerations for Solubility:

  • Polarity: If the compound has a polar functional group, it may exhibit higher solubility in polar solvents like water or ethanol.
  • Hydrophobic Character: The presence of hydrophobic aromatic rings, such as the 4-chlorophenyl group, can reduce solubility in polar solvents, whereas enhancing solubility in organic solvents.
  • Temperature: Solubility often increases with temperature; thus experimental conditions can change solubility characteristics.
  • pH Levels: For amines, adjustments in pH can affect the ionization state, altering their solubility behavior in aqueous solutions.

In practical applications, it is essential to explore the relative solubility in various solvents to determine the most effective formulation for both laboratory and therapeutic use. As highlighted in various studies, understanding the solubility of such compounds aids in predicting their behavior in biological systems and their potential use in drug development.

In conclusion, while detailed empirical data is crucial for precise solubility values, the inherent properties of N-[[3-(4-chlorophenyl)isoxazol-5-yl]methyl]-N-ethyl-ethanamine suggest a consideration of the above factors when evaluating its solubility profile.

Interesting facts

Interesting Facts about N-[[3-(4-chlorophenyl)isoxazol-5-yl]methyl]-N-ethyl-ethanamine

N-[[3-(4-chlorophenyl)isoxazol-5-yl]methyl]-N-ethyl-ethanamine is a fascinating compound in the field of medicinal chemistry, showcasing a unique combination of structural features that contribute to its potential therapeutic applications.

Key Features

  • Isoxazole Ring: The compound incorporates an isoxazole ring, which is known for its diverse biological activities, including anti-inflammatory and antioxidant properties.
  • Chlorophenyl Group: The presence of the 4-chlorophenyl moiety enhances the compound's biological activity and lipophilicity, potentially improving its interaction with biological targets.
  • Amine Functionality: The amine functional group in the structure plays a critical role in the compound’s reactivity and ability to form bonds, which is essential for its biological efficacy.

This compound has garnered attention in research circles, especially for its potential applications in treating various health conditions, owing to its carefully crafted structure. As one expert noted, "The intricate balance of electronic and steric properties in N-[[3-(4-chlorophenyl)isoxazol-5-yl]methyl]-N-ethyl-ethanamine makes it a subject of intense investigation in modern pharmacology."

Potential Applications

Researchers are exploring the compound's capability in:

  • Targeting specific pathways in cancer therapy
  • Possessing neuroprotective effects due to its interactions with neuronal pathways
  • Potentially acting as a scaffold for the development of new pharmaceuticals

In summary, N-[[3-(4-chlorophenyl)isoxazol-5-yl]methyl]-N-ethyl-ethanamine represents the innovative intersection of organic chemistry and pharmacology, and continues to be a promising candidate for future drug development initiatives. Its multifaceted structures not only enhance its utility but also present an exciting challenge for chemists to unlock its full potential.