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Deferoxamine

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Identification
Molecular formula
C25H48N6O8
CAS number
70-51-1
IUPAC name
N-[3-[5-[3-[acetyl(hydroxy)amino]propyl]-3,6-dioxo-piperazin-2-yl]propyl]-N-hydroxy-acetamide
State
State

Deferoxamine is a solid at room temperature and is often provided as a mesylate salt for enhanced stability and solubility. The mesylate form may appear as a white to light brown amorphous powder.

Melting point (Celsius)
152.00
Melting point (Kelvin)
425.00
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
561.67g/mol
Molar mass
561.6740g/mol
Density
0.7004g/cm3
Appearence

Deferoxamine is typically an amorphous, white to off-white powder. It is usually odorless and can easily absorb moisture from the air (hygroscopic).

Comment on solubility

Solubility Characteristics

The compound N-[3-[5-[3-[acetyl(hydroxy)amino]propyl]-3,6-dioxo-piperazin-2-yl]propyl]-N-hydroxy-acetamide exhibits interesting solubility properties that are crucial for its potential applications. Understanding solubility can often be a complex endeavor as it is influenced by numerous factors, including molecular structure, temperature, and the nature of the solvent.

Key Solubility Insights

  • Polarity: The presence of multiple functional groups, such as hydroxy and amino moieties, enhances the compound's hydrogen bonding capabilities, potentially increasing solubility in polar solvents like water.
  • Hydrophobic Regions: The hydrophobic areas of the molecule may lead to decreased solubility in strictly polar solvents, suggesting that it could be more soluble in a mixed solvent system.
  • pH Dependency: The solubility may vary with changes in pH, especially due to the presence of basic (amino) and acidic (acetyl) groups. Therefore, the pH of the solution needs to be carefully controlled.
  • Concentration Effects: At high concentrations, solubility may decrease, leading to precipitation. Understanding the saturation point is critical for applications.

In summary, while this compound is anticipated to have a favorable solubility profile in polar solvents, the exact behavior is subject to the aforementioned factors. As one expert noted, "The interplay of functional groups within a molecular structure often dictates solubility preferences." Thus, further empirical investigation is recommended to ascertain precise solubility parameters.

Interesting facts

Interesting Facts about N-[3-[5-[3-[acetyl(hydroxy)amino]propyl]-3,6-dioxo-piperazin-2-yl]propyl]-N-hydroxy-acetamide

N-[3-[5-[3-[acetyl(hydroxy)amino]propyl]-3,6-dioxo-piperazin-2-yl]propyl]-N-hydroxy-acetamide, often referred to as a complex organic compound with notable structural attributes, presents intriguing possibilities in the realms of medicinal chemistry and pharmacology. Here are some captivating insights:

  • Structural Diversity: This compound features a rich molecular architecture that includes piperazinyl groups and acetylamino functionalities, which could potentially enhance biological activity by allowing for varied interactions with biological targets.

  • Potential Therapeutic Applications: The presence of acetyl and hydroxy functionalities hints at possible use in drug delivery systems or as a precursor for synthesizing larger, more complex therapeutic agents, particularly in treating diseases that involve piperazine derivatives.

  • Biochemical Interactions: The acetamide group is known for its ability to form hydrogen bonds, making this compound a candidate for studies involving enzyme inhibition or modulation, which could lead to the development of new drugs.

  • Research Importance: Compounds with intricate structures like this are important in medicinal chemistry as they help in understanding structure-activity relationships, paving the way for the design of more effective pharmaceutical agents.

  • In Silico Studies: The compound is also suitable for computational studies, allowing scientists to model its interactions and predict activity, which accelerates the drug discovery process.

In conclusion, N-[3-[5-[3-[acetyl(hydroxy)amino]propyl]-3,6-dioxo-piperazin-2-yl]propyl]-N-hydroxy-acetamide stands as a testament to the complexity and potential of organic compounds in modern chemistry. This compound’s intricate nature underscores the beauty of chemical research and its endless possibilities for impacting human health and sciences.

Synonyms
N-[3-[5-[3-[acetyl(hydroxy)amino]propyl]-3,6-dioxopiperazin-2-yl]propyl]-N-hydroxyacetamide
Rhodotulic acid
(2S-cis)-N,N'-((3,6-Dioxopiperazine-2,5-diyl)di-3,1-propanediyl)bis(N-hydroxyacetamide)
chromic rhodotorulic acid
SCHEMBL472938
CHEMBL322490
PUWVNTVQJFSBDH-UHFFFAOYSA-N
DB-044703
NS00052751
Q7321233
Acetamide,N'-[(3,6-dioxo-2,5-piperazinediyl)di-3,1-propanediyl]bis[N-hydroxy-, (2S-cis)-
Acetohydroxamic acid,N'-[(3,6-dioxo-2,5-piperazinediyl)bis(trimethylene)]di-, L-
N-[3-[5-[3-[acetyl(hydroxy)amino]propyl]-3,6-dioxo-piperazin-2-yl]propyl]-N-hydroxy-acetamide