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Furaltadone

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Identification
Molecular formula
C8H7N3O5
CAS number
139-91-3
IUPAC name
N-[3-(5-nitro-2-furyl)-6H-1,2,4-oxadiazin-6-yl]acetamide
State
State

Furaltadone is in a solid state at room temperature. As a crystalline powder, it may be susceptible to caking if exposed to moisture.

Melting point (Celsius)
224.00
Melting point (Kelvin)
497.15
Boiling point (Celsius)
555.20
Boiling point (Kelvin)
828.35
General information
Molecular weight
225.16g/mol
Molar mass
225.1590g/mol
Density
1.4900g/cm3
Appearence

Furaltadone typically appears as a pale yellow or yellow crystalline powder. It may also appear as a solid aggregate due to its powdery nature.

Comment on solubility

Solubility of N-[3-(5-nitro-2-furyl)-6H-1,2,4-oxadiazin-6-yl]acetamide

The solubility of N-[3-(5-nitro-2-furyl)-6H-1,2,4-oxadiazin-6-yl]acetamide can be quite intriguing given its structural complexities. This compound falls under the category of heterocyclic organic compounds, and its solubility characteristics can be influenced by several factors, which include:

  • Polarity: The presence of nitro and acetamide functional groups tends to enhance polarity, which may increase solubility in polar solvents.
  • Hydrogen Bonding: The ability to form hydrogen bonds due to the acetamide group can aid in solubilization in water or other hydrogen-bonding solvents.
  • Solvent Choice: Common solvents such as water, DMSO, and methanol may show varying degrees of effectiveness in dissolving this compound.

However, empirical studies are essential to determine the exact solubility limits. As a general note, compounds with similar structures often exhibit:

  1. Higher solubility in organic solvents due to hydrophobic characteristics of the furan ring.
  2. Moderate to low solubility in water, largely depending on the concentration and temperature.

In conclusion, while theoretical predictions can offer insights into solubility behaviors, experimental data will ultimately provide the most accurate information regarding the solubility of N-[3-(5-nitro-2-furyl)-6H-1,2,4-oxadiazin-6-yl]acetamide in various solvents.

Interesting facts

Interesting Facts about N-[3-(5-nitro-2-furyl)-6H-1,2,4-oxadiazin-6-yl]acetamide

N-[3-(5-nitro-2-furyl)-6H-1,2,4-oxadiazin-6-yl]acetamide is a fascinating compound that has garnered significant interest in the field of medicinal chemistry. This compound can be analyzed through various perspectives:

1. Chemical Structure and Composition

  • Oxadiazin Ring: The structure features a six-membered oxadiazin ring, which is known for its biological activity and ability to interact with various biomolecules.
  • Nitro Group: The presence of the nitro group (–NO2) in the furan moiety contributes to the compound's electron-withdrawing properties, enhancing its reactivity.
  • Furan Derivative: As a derivative of furan, this compound may exhibit unique properties, including potential anti-inflammatory and antioxidant activities, making it worth further exploration.

2. Biological Significance

  • Pharmacological Potential: Compounds containing oxadiazin rings have been identified in various pharmacological studies as having antibacterial, antifungal, or anticancer properties.
  • Research Applications: The unique structure of N-[3-(5-nitro-2-furyl)-6H-1,2,4-oxadiazin-6-yl]acetamide allows for potential development into new therapeutic agents.
  • Functionalization: This compound serves as a versatile platform for further modifications, which can tailor its bioactivity through synthetic organic chemistry.

3. Synthetic Considerations

  • Synthesis Challenges: The synthesis of this compound may involve multi-step procedures, often including reaction conditions that require careful optimization.
  • Green Chemistry: Researchers are focusing on synthesizing such compounds through environmentally friendly methods that reduce waste and energy consumption.

As a fascinating compound within the realm of synthetic and medicinal chemistry, N-[3-(5-nitro-2-furyl)-6H-1,2,4-oxadiazin-6-yl]acetamide exemplifies the intricate relationship between chemical structure and biological function. Its study not only contributes to our understanding of complex molecules but also paves the way for developing innovative therapeutic solutions.

Synonyms
DTXSID30946962
N-[3-(5-Nitrofuran-2-yl)-6H-1,2,4-oxadiazin-6-yl]ethanimidic acid