Fumagillin | Solubility of Things

Identification

Molecular formula

C₂₆H₃₄O₇

CAS number

23110-15-8

IUPAC name

N-[3-(6,16-dihydroxy-7-methyl-2-oxo-3-oxabicyclo[10.4.0]hexadeca-1(12),9,13,15-tetraen-4-yl)prop-1-enyl]hepta-2,4-dienamide

State

At room temperature, fumagillin is a solid. It is available in its crystalline form and is typically handled as a solid in laboratory settings.

Melting point (Celsius)

196.50

Melting point (Kelvin)

469.70

Boiling point (Celsius)

705.60

Boiling point (Kelvin)

978.80

General information

Molecular weight

458.55g/mol

Molar mass

458.5500g/mol

Density

1.3000g/cm³

Appearence

Fumagillin appears as a yellow-orange crystalline substance. It is known for its characteristic color which makes it distinguishable.

Comment on solubility

Solubility of N-[3-(6,16-dihydroxy-7-methyl-2-oxo-3-oxabicyclo[10.4.0]hexadeca-1(12),9,13,15-tetraen-4-yl)prop-1-enyl]hepta-2,4-dienamide

The solubility of the compound N-[3-(6,16-dihydroxy-7-methyl-2-oxo-3-oxabicyclo[10.4.0]hexadeca-1(12),9,13,15-tetraen-4-yl)prop-1-enyl]hepta-2,4-dienamide (C₂₆H₃₄O₇) is a subject of significant interest due to its complex structure and diverse functional groups. Solubility can be influenced by several factors, including:

Polarity: The presence of hydroxyl (-OH) groups in the structure enhances the compound's ability to form hydrogen bonds with polar solvents, such as water.
Chain Length: The extensive carbon backbone contributes to hydrophobic interactions which may limit solubility in aqueous environments.
Functional Groups: Multiple functional groups, including keto and oxabicyclic units, can significantly alter solubility characteristics.

As a result, one might find that:

This compound is likely more soluble in organic solvents such as ethanol or dimethyl sulfoxide (DMSO) rather than in water.
In aqueous solutions, it may exhibit limited solubility, especially at lower temperatures.

In summary, the solubility profile of this compound is complex, and experimental data is essential to fully understand its solubility characteristics. Understanding such solubility behavior is crucial for its potential applications in fields like pharmaceuticals and material science.

Interesting facts

Exploring N-[3-(6,16-dihydroxy-7-methyl-2-oxo-3-oxabicyclo[10.4.0]hexadeca-1(12),9,13,15-tetraen-4-yl)prop-1-enyl]hepta-2,4-dienamide

This complex compound, known as N-[3-(6,16-dihydroxy-7-methyl-2-oxo-3-oxabicyclo[10.4.0]hexadeca-1(12),9,13,15-tetraen-4-yl)prop-1-enyl]hepta-2,4-dienamide, descends from an intriguing class of organic molecules characterized by their unique structures and potential biological activities. With its distinct bicyclic configuration and multiple functional groups, this compound invites exploration on various fronts:

Structure Diversity: The compound features a bicyclo structure, combining carbon rings with a variety of functional groups - a hallmark of many natural products.
Biological Relevance: Compounds with similar structures have attracted significant interest in pharmacology for their potential therapeutic properties, including anti-inflammatory and antioxidant activities.
Complexity and Synthesis: The intricate nature of this molecule underscores challenges in synthesis, opening doors for innovative synthetic methodologies and strategies in organic chemistry.
Potential Applications: Due to its unique constitution, it could serve as a lead compound for drug development or as a biological probe, further expanding its significance in medicinal chemistry.

Overall, this compound exemplifies how structural complexity can correlate with functional diversity, making it a valuable subject for continued research and development. As the statement goes, "In complexity, there is beauty and potential." It is fascinating to consider how exploring such compounds can lead to new discoveries in the fields of chemistry and medicine!