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Iobenzamic acid

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Identification
Molecular formula
C17H15I3NO2
CAS number
21807-90-9
IUPAC name
N-(3-acetonyl-2,4,6-triiodo-phenyl)-N-benzyl-acetamide
State
State

At room temperature, Iobenzamic acid is in a solid state. It is generally stable under standard conditions of temperature and pressure, making it suitable for use in various applications, particularly in medical imaging.

Melting point (Celsius)
175.00
Melting point (Kelvin)
448.15
Boiling point (Celsius)
419.00
Boiling point (Kelvin)
692.15
General information
Molecular weight
539.11g/mol
Molar mass
539.1080g/mol
Density
2.2360g/cm3
Appearence

Iobenzamic acid appears as a white to off-white crystalline solid. It is typically processed into a powder form for pharmaceutical use, given its application in imaging contrast media. Its structure, incorporating iodine atoms, contributes to its dense appearance similar to other iodine-containing compounds.

Comment on solubility

Solubility of N-(3-acetonyl-2,4,6-triiodo-phenyl)-N-benzyl-acetamide

The solubility of N-(3-acetonyl-2,4,6-triiodo-phenyl)-N-benzyl-acetamide is an interesting aspect of its chemical behavior. Being a complex organic compound, its solubility can vary significantly depending on several factors:

  • Polarity: This compound exhibits both polar and nonpolar characteristics due to the presence of various functional groups.
  • Temperature: Solubility often increases with temperature, making it more dissolvable in warm solvents.
  • Solvent type: N-(3-acetonyl-2,4,6-triiodo-phenyl)-N-benzyl-acetamide is likely to show better solubility in organic solvents such as ethanol, dichloromethane, and acetone rather than in water.

While solubility in water is typically limited due to the hydrophobic benzyl group and the triiodo-substituents, organic solvents can aid in the compound’s dissolution due to favorable interactions. As a general note, this compound may not be readily soluble in highly polar solvents.

In conclusion, the solubility of this compound is affected by its structure and the medium in which it is placed. Understanding solubility not only plays a critical role in its application but also in its behavior in various chemical reactions.

Interesting facts

Interesting Facts about N-(3-acetonyl-2,4,6-triiodo-phenyl)-N-benzyl-acetamide

N-(3-acetonyl-2,4,6-triiodo-phenyl)-N-benzyl-acetamide is a fascinating compound that has attracted interest in various fields, particularly in medicinal chemistry and organic synthesis. Here are some captivating points about this compound:

  • Unique Structure: The molecular structure of this compound includes a phenyl group that has three iodine atoms substituted at specific positions. This tri-iodo substitution is of great interest because iodine is known for its unique properties in enhancing the biological activity of compounds.
  • Potential Biochemical Applications: Compounds containing iodine, such as this one, often exhibit potent biological activity. They may be investigated for their roles in developing new therapeutic agents, particularly in the treatment of diseases where iodine plays a therapeutic role, such as in some forms of cancer.
  • Research Interests: The incorporation of the acetonyl group offers possibilities for various reactions, which is why researchers are keen on understanding how it can be utilized in pharmaceutical synthesis as a precursor in drug development.
  • Synthesis and Methods: The synthesis of N-(3-acetonyl-2,4,6-triiodo-phenyl)-N-benzyl-acetamide showcases the fascinating interplay of organic reactions, revealing a wealth of methodologies such as acylation and coupling reactions. These techniques are pivotal for creating complex organic molecules with precision.
  • Environmental Considerations: As we explore compounds with iodine substituents, it’s important to consider their environmental impact and degradation pathways. Understanding these aspects helps in designing greener synthetic approaches and evaluating the safety of these compounds.

The study of compounds like N-(3-acetonyl-2,4,6-triiodo-phenyl)-N-benzyl-acetamide exemplifies how chemical research continuously evolves, addressing both scientific curiosity and real-world applications. As quoted from renowned chemists, "The beauty of chemistry lies not just in understanding existing compounds but also in discovering new possibilities."

Further research on this intriguing compound will undoubtedly shed light on its properties and potential applications, highlighting the ongoing significance of chemical innovation.