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Noscapine

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Identification
Molecular formula
C22H23NO7
CAS number
128-62-1
IUPAC name
N-[(3-allyl-4a,9-dihydroxy-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-ylidene)amino]benzamide
State
State

Noscapine is generally found in a solid state at room temperature, existing as a crystalline powder.

Melting point (Celsius)
176.00
Melting point (Kelvin)
449.00
Boiling point (Celsius)
537.00
Boiling point (Kelvin)
810.00
General information
Molecular weight
413.43g/mol
Molar mass
413.4530g/mol
Density
1.4785g/cm3
Appearence

Noscapine typically appears as a white crystalline solid. It is often used in its hydrochloride salt form, which enhances its solubility in water.

Comment on solubility

Solubility Overview

The solubility of N-[(3-allyl-4a,9-dihydroxy-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-ylidene)amino]benzamide (C22H23NO7) can be influenced by several factors due to its complex molecular structure. Understanding the solubility parameters can be vital for practical applications, especially in pharmaceutical formulations. Here are some key points:

  • Polarity: Solubility is largely affected by the polarity of the compound. The presence of multiple hydroxyl groups in the structure may enhance solubility in polar solvents, such as water.
  • Solvent Choice: If you consider non-polar solvents, this compound may exhibit low solubility due to its aromatic and complex functional groups.
  • Hydrogen Bonding: The ability to form hydrogen bonds with solvents can play a significant role; therefore, solvents capable of hydrogen bonding, like alcohols, might show better solubility with this compound.
  • Temperature Effects: Solubility can also vary with temperature; generally, increased temperature results in enhanced solubility for solids and some liquids.

In summary, exploring solubility for N-[(3-allyl-4a,9-dihydroxy-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-ylidene)amino]benzamide requires careful measurement and consideration of these dynamic factors. As noted, "the chemistry of solubility is as intricate as the science of molecules themselves." Understanding and manipulating these can lead to improved functionality in various applications.

Interesting facts

Interesting Facts about N-[(3-allyl-4a,9-dihydroxy-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-ylidene)amino]benzamide

This compound, known primarily in the research community for its complex structure and potential applications, showcases the fascinating interplay of organic chemistry and medicinal research. Here are some intriguing aspects:

  • Structural Complexity: The compound features a unique combination of a benzamide moiety and an isoquinoline derivative, which contributes to its intricate three-dimensional structure. This complexity often influences the compound's function in biological systems.
  • Potential Therapeutic Applications: Compounds with similar structures to this molecule have been explored for their pharmacological properties, including anti-cancer and anti-inflammatory effects. Their ability to interact with biological targets could lead to the development of novel therapeutic agents.
  • Natural Product Inspiration: Many benzofuro[3,2-e]isoquinolines are derived from natural sources, indicating that this compound's structure can sometimes be linked to natural products that play significant roles in traditional medicine.
  • Research Interest: Due to its structural characteristics, this compound is a subject of interest for researchers in organic synthesis and drug design. Understanding its reactivity could pave the way for new synthetic pathways.
  • Synthetic Challenges: The synthesis of complex organic molecules like this one poses several challenges, including the careful management of chiral centers and functional groups, making it a popular topic in advanced organic chemistry courses and research projects.

The exploration of such chemical entities not only deepens our understanding of organic structures but also propels forward the exciting field of drug discovery. As researchers delve deeper into the potential of this compound, who knows what groundbreaking discoveries await!

Synonyms
Nalbzoh
N-[(4a,9-dihydroxy-3-prop-2-enyl-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-ylidene)amino]benzamide
HMS3267J08
Q27163513
N-[(4a,9-Dihydroxy-3-prop-2-enyl-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-ylidene)amino]benzamide