Interesting facts
Interesting Facts about N-(3-amino-4-methyl-phenyl)acetamide
N-(3-amino-4-methyl-phenyl)acetamide, often referred to by its systematic name or simply as an acetamide derivative, is a fascinating compound in the realm of organic chemistry. Here are some intriguing aspects of this compound:
- Biological Relevance: This compound serves as an important intermediate in the synthesis of various pharmaceuticals, particularly in the development of analgesic and anti-inflammatory drugs. Its structural features can enhance biological activity or alter pharmacokinetics.
- Amine Group Influence: The presence of the amino group in this derivative plays a critical role in determining its reactivity and interaction with other molecules. Amine-containing compounds are often involved in hydrogen bonding, which can greatly affect their solubility and reactivity.
- Structure-Activity Relationship (SAR): The unique arrangement of the amino and methyl groups on the phenyl ring influences the compound's biological properties. In studying SAR, chemists can predict how modifications to its structure may enhance or inhibit its activity.
- Synthesis: The compound can be synthesized through various methods, including nucleophilic substitution reactions. Understanding the mechanisms behind these syntheses is crucial for chemists aiming to create more efficient pathways in drug design.
- Interdisciplinary Studies: Research on N-(3-amino-4-methyl-phenyl)acetamide often overlaps with fields such as medicinal chemistry and toxicology. This makes it a valuable compound for interdisciplinary studies, offering insights that can lead to novel therapeutic agents.
In conclusion, N-(3-amino-4-methyl-phenyl)acetamide exemplifies the intricate relationship between structure and function in pharmaceuticals. As we continue to explore its properties, we uncover the vast potential it holds for improving therapeutic outcomes and developing new medicinal compounds.
Synonyms
N-(3-Amino-4-methylphenyl)acetamide
4-Acetylamino-2-aminotoluene
Acetamide, N-(3-amino-4-methylphenyl)-
CCRIS 2681
3'-Amino-p-acetotoluidide
UNII-HTV7P28A6R
EINECS 228-933-0
HTV7P28A6R
p-Acetotoluidide, 3'-amino-
BRN 2804114
5-acetamido-2-methylaniline
4-acetoxyamino-2-aminotoluene
ACETANILIDE, 3'-AMINO-4'-METHYL-
DTXSID1064293
N(4)-acetyl-2,4-toluenediamine
4-ACETYLAMINO-2-TOLUIDINE
2-13-00-00062 (Beilstein Handbook Reference)
N(4)-Ac-TDA
DTXCID8044098
228-933-0
6375-16-2
2-Amino-4-acetylaminotoluene
3'-Amino-4'-methylacetanilide
N-(3-Amino-4-methyl-phenyl)-acetamide
4-acetamino-2-aminotoluene
Oprea1_151592
Oprea1_544035
2-Methyl-5-acetamido aniline
SCHEMBL2081736
ALBB-031746
GAA37516
MFCD00025202
STL411751
AKOS000100559
N-(3-amino-4-methyl-phenyl)acetamide
N-(3-amino-4-methylphenyl)-acetamide
N-(3-amino-4-methyl-phenyl) acetamide
DA-18418
LS-11555
CS-0370446
NS00035546
EN300-39556
G29235
AE-641/03220028
N-(3-Amino-4-methylphenyl)acetamide, AldrichCPR
Q27280094
Z274783012
Solubility of N-(3-amino-4-methyl-phenyl)acetamide
N-(3-amino-4-methyl-phenyl)acetamide, also known as p-toluidine acetamide, exhibits varying solubility characteristics influenced by its molecular structure. Understanding its solubility is crucial for applications in medicinal chemistry and biochemistry.
Solubility Details:
In conclusion, understanding the solubility of N-(3-amino-4-methyl-phenyl)acetamide is essential for optimizing its application in different chemical environments. As emphasized, the interplay of functional groups and solvent polarity plays a pivotal role in determining its solubility profile.