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3-Acetamidophenylamine

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Identification
Molecular formula
C8H10N2O
CAS number
709-72-0
IUPAC name
N-(3-aminophenyl)acetamide
State
State

The compound is a solid at room temperature.

Melting point (Celsius)
188.00
Melting point (Kelvin)
461.15
Boiling point (Celsius)
388.00
Boiling point (Kelvin)
661.15
General information
Molecular weight
150.18g/mol
Molar mass
150.1730g/mol
Density
1.2933g/cm3
Appearence

3-Acetamidophenylamine typically appears as a white to off-white crystalline powder. It is solid at room temperature and can vary in slight shading depending on purity and specific storage conditions.

Comment on solubility

Solubility of N-(3-aminophenyl)acetamide

The solubility of N-(3-aminophenyl)acetamide can be quite interesting, showcasing its behavior in various solvents. This compound is known for its moderate solubility characteristics, which can be affected by several factors:

  • Polarity of the solvent: N-(3-aminophenyl)acetamide typically exhibits better solubility in polar solvents due to its amine and acetamide groups that can engage in hydrogen bonding.
  • Temperature: Increasing the temperature generally enhances the solubility of organic compounds; thus, slight heating may improve solubility.
  • pH levels: The solubility of this compound can also vary with changes in pH, especially due to the presence of the amino group, which can accept protons and affect solubility in acidic or basic conditions.

In summary, while N-(3-aminophenyl)acetamide is fairly soluble in polar solvents, factors such as polarity, temperature, and pH should be carefully considered when determining its solubility properties. The compound serves as a fascinating example of how molecular structure and solvent interactions can dictate solubility behavior.

Interesting facts

Interesting Facts about N-(3-aminophenyl)acetamide

N-(3-aminophenyl)acetamide, also known as 3-aminoacetanilide, is a fascinating organic compound with a variety of applications in both chemistry and biochemistry. Here are some noteworthy aspects of this compound:

  • Pharmaceutical Relevance: This compound has garnered interest in the pharmaceutical industry due to its potential use as an analgesic and anti-inflammatory agent. It serves as a precursor for various drug formulations.
  • Research Applications: N-(3-aminophenyl)acetamide is often used in research to explore the structure-activity relationship of amide compounds. Understanding how structural variations affect biological activity can lead to new therapeutic avenues.
  • Synthesis Techniques: This compound can be synthesized through several methods, including acylation of 3-aminophenylamine. Its synthesis is a good example of applying basic organic chemistry skills in the lab.
  • Biological Activity: Preliminary studies have indicated that derivatives of N-(3-aminophenyl)acetamide may exhibit antimicrobial properties. This has led to further research on its role in fighting infections.
  • Chemical Versatility: The presence of the amino and acetamide functional groups provides this compound with properties that can be modified for various applications, such as in synthesizing dyes and other organic materials.

As noted by some researchers, "the ability to manipulate the molecular structure of compounds like N-(3-aminophenyl)acetamide is crucial for advancing our understanding of medicinal chemistry." This flexibility opens doors for innovation in drug design and development.

In conclusion, N-(3-aminophenyl)acetamide is not only an important chemical entity in laboratories but also holds promise for future research and development in multiple fields.

Synonyms
N-(3-Aminophenyl)acetamide
102-28-3
3'-Aminoacetanilide
M-AMINOACETANILIDE
3-Acetamidoaniline
Acetamide, N-(3-aminophenyl)-
3-Aminoacetanilide
M-Acetaminoaniline
m-(Acetylamino)aniline
3-Amino-N-acetylaniline
3-Aminoacetanilid
N-Acetyl-m-phenylenediamine
3-Acetylaminoaniline
Acetanilide, 3'-amino-
1-Amino-3-(acetylamino)benzene
3-Acetamidoanilide
3-Aminoacetanilid [Czech]
3-(Acetylamino)aniline
m-Acetamidoaniline
N-Acetyl-m-fenylendiamin
CCRIS 4574
NSC 165576
N-Acetyl-m-fenylendiamin [Czech]
EINECS 203-021-5
MFCD00025229
N-Acetyl-1,3-diaminobenzene
BRN 0775952
N-Acetyl-m-fenylenediamin
Q5K7HYS7JJ
MLS002415739
N-Acetyl-1,3-phenylenediamine
DTXSID2024454
1-ACETYLAMINO-3-AMINOBENZENE
NSC-165576
SMR001370905
N1-(3-Aminophenyl)acetamide
N-(3-aminophenyl)-acetamide
3Aminoacetanilid
mAcetaminoaniline
N-(3-Amino-phenyl)-acetamide
3'aminoacetanilide
3acetylaminoaniline
3AminoNacetylaniline
NAcetylmfenylendiamin
3'-aminoacetanilinde
3'-aminoacetoanilide
m(Acetylamino)aniline
3'-amino-acetanilide
3-acetylamino-aniline
Acetanilide, 3'amino
NAcetylmphenylenediamine
N(3Aminophenyl)acetamide
UNII-Q5K7HYS7JJ
M-ACETYLAMINOANILINE
WLN: ZR CMV1
1Amino3(acetylamino)benzene
cid_7604
Acetamide, N(3aminophenyl)
3'-Aminoacetanilide, 97%
AMINOACETANILIDE, M-
N-(3-aminophenyl)ethanamide
SCHEMBL374432
N-(3-Aminophenyl)acetamide #
DTXCID304454
3-ACETYLAMINOBENZENEAMINE
CHEMBL1606123
BDBM74413
HMS3039A15
ALBB-025724
STR05687
Tox21_200881
BBL009447
NSC165576
STK397585
3-(METHYLCARBONYLAMINO)ANILINE
AKOS000108317
CS-W019904
PB39397
NCGC00091315-01
NCGC00091315-02
NCGC00258435-01
AC-10864
BP-10965
CAS-102-28-3
SY006038
A1533
NS00021450
EN300-17408
P19657
AE-562/40191150
BRD-K46780692-001-03-5
Q27463669
Z56926524
F3377-0755
InChI=1/C8H10N2O/c1-6(11)10-8-4-2-3-7(9)5-8/h2-5H,9H2,1H3,(H,10,11
203-021-5
N3M