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Disulfiram

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Identification
Molecular formula
C10H20N2O4S4
CAS number
97-77-8
IUPAC name
N'-[[(3-anilino-3-oxo-propanoyl)amino]disulfanyl]-N-phenyl-propanediamide
State
State

At room temperature, Disulfiram is a solid. It is stable and does not readily oxidize or degrade when kept in appropriate storage conditions.

Melting point (Celsius)
70.00
Melting point (Kelvin)
343.00
Boiling point (Celsius)
300.00
Boiling point (Kelvin)
573.00
General information
Molecular weight
296.54g/mol
Molar mass
296.5380g/mol
Density
1.2500g/cm3
Appearence

Disulfiram appears as a white to off-white crystalline powder. It is mostly odorless but can have a slight sulfur-like odor. The crystals may vary in size and are relatively stable under normal handling conditions.

Comment on solubility

Solubility of N'-[[(3-anilino-3-oxo-propanoyl)amino]disulfanyl]-N-phenyl-propanediamide

The solubility of N'-[[(3-anilino-3-oxo-propanoyl)amino]disulfanyl]-N-phenyl-propanediamide can be influenced by several factors due to its complex structure. Understanding its solubility is vital for applications in pharmaceuticals and chemical synthesis. Here are some key considerations:

  1. Polarity: This compound contains both polar and non-polar functional groups, affecting its solubility in different solvents. Compounds with significant polar characteristics tend to be more soluble in polar solvents such as water.
  2. Temperature: Like many chemical compounds, solubility may increase with temperature. This is particularly true for solid compounds that dissolve better when heated.
  3. pH Level: The solubility can also be pH-dependent, especially for compounds containing amine and carboxylic acid groups. Altering the pH can enhance the ionization of the amine groups, increasing solubility in aqueous solutions.
  4. Interactions: The presence of disulfide bonds and potential intermolecular interactions, such as hydrogen bonding, can also play a role in determining solubility.

Overall, while the definitive solubility of this compound may require experimental determination, it is essential to keep in mind these factors that significantly influence how and where this chemical can be dissolved efficiently.

Interesting facts

Interesting Facts about N'-[[(3-anilino-3-oxo-propanoyl)amino]disulfanyl]-N-phenyl-propanediamide

N'-[[(3-anilino-3-oxo-propanoyl)amino]disulfanyl]-N-phenyl-propanediamide, a fascinating compound, belongs to the class of amides and is valued for its unique structural features and properties. Here are some compelling facts about this compound:

  • Complex Structure: This compound contains a disulfide linkage, which is significant in biological systems for stabilizing protein structures and impacts the compound's reactivity.
  • Biological Relevance: Its structure suggests potential utility in pharmaceutical research, particularly in the design of drug candidates that can interact with specific biological targets due to its aniline and amide functionalities.
  • Potential Applications: Given its intricate chemical makeup, it may be explored in areas such as:
    • Antioxidant activity: The disulfide bond could confer redox activity, useful in scavenging free radicals.
    • Anticancer research: Due to the presence of the aniline and oxo-propanoyl groups, it may exhibit selective toxicity toward cancer cells.
    • Protein interaction studies: The compound may help in understanding protein folding and stability.
  • Research and Development: Ongoing studies may focus on synthesizing derivatives to enhance its biological activity or reduce toxicity, providing insight into structure-activity relationships.
  • Insightful Quotation: As a common saying in chemistry goes, "The structure dictates the function," highlighting the importance of this compound’s unique architecture in its potential applications.

This compound is an excellent example of how structural modifications can lead to diverse biological functions and pave the way for innovations in drug development.