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N-(3-benzoylphenyl)-1,1-difluoro-methanesulfonamide

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Identification
Molecular formula
C14H11F2NO3S
CAS number
904123-16-0
IUPAC name
N-(3-benzoylphenyl)-1,1-difluoro-methanesulfonamide
State
State
In standard conditions, N-(3-benzoylphenyl)-1,1-difluoro-methanesulfonamide is a solid. It is generally managed in its powdered form for synthesis and analysis purposes.
Melting point (Celsius)
145.00
Melting point (Kelvin)
418.15
Boiling point (Celsius)
307.00
Boiling point (Kelvin)
580.15
General information
Molecular weight
309.31g/mol
Molar mass
309.2920g/mol
Density
1.4110g/cm3
Appearence

N-(3-benzoylphenyl)-1,1-difluoro-methanesulfonamide typically appears as a white to off-white crystalline powder. It is often used in research and has distinct crystalline characteristics.

Comment on solubility

Solubility of N-(3-benzoylphenyl)-1,1-difluoro-methanesulfonamide

The solubility of N-(3-benzoylphenyl)-1,1-difluoro-methanesulfonamide is an important factor to consider in its application and use. This compound exhibits variable solubility depending on the solvent used, which can help predict its behavior in different environments. Here are some key points regarding its solubility:

  • Solvent Dependent: It is often more soluble in polar organic solvents due to the presence of sulfonamide functional groups.
  • Limited Water Solubility: Generally, compounds with large aromatic systems and fluorine substituents exhibit lower water solubility.
  • Influence of Temperature: Solubility can increase with temperature, making the compound more feasible for certain applications at elevated temperatures.
  • Complex Formation: This compound can potentially form complexes with other molecules, enhancing or altering its solubility profile.

As stated, "the solubility of a compound is one of the key elements in determining its utility and behavior in various chemical applications." Thus, understanding the solubility landscape of N-(3-benzoylphenyl)-1,1-difluoro-methanesulfonamide is crucial for its effective use in pharmaceuticals or organic synthesis.

Interesting facts

Interesting Facts about N-(3-benzoylphenyl)-1,1-difluoro-methanesulfonamide

N-(3-benzoylphenyl)-1,1-difluoro-methanesulfonamide is a unique compound that plays a significant role in various scientific fields. Here are some fascinating insights regarding this compound:

  • Chemical Structure: This compound is characterized by its difluoromethanesulfonamide group, which imparts specific chemical reactivity, making it essential in synthetic chemistry.
  • Pharmaceutical Relevance: Compounds like this one are often studied for their potential applications in drug development, particularly in designing new therapies that can target specific biological pathways.
  • Fluorine Substituents: The presence of fluorine atoms in the structure can enhance the lipophilicity of the compound, aiding in cell membrane penetration and influencing the biological distribution of the compound within living organisms.
  • Use in Material Science: The sulfonamide functionality is often associated with improved thermal stability of polymers, making this compound an interesting candidate for use in advanced materials.

Furthermore, researchers are keen on understanding the mechanistic pathways by which N-(3-benzoylphenyl)-1,1-difluoro-methanesulfonamide interacts with specific proteins or enzymes, which can lead to groundbreaking discoveries in both chemical synthesis and medicinal chemistry.

In scientific texts, you might often find that such compounds are referred to as "bioisosteres," meaning they can mimic the effects of different molecules while altering their pharmacokinetic properties. This makes them a crucial area of study in the quest for improved therapeutics.

Ultimately, the exploration of N-(3-benzoylphenyl)-1,1-difluoro-methanesulfonamide exemplifies the intricate connection between chemical structure, reactivity, and practical application in science. The future holds great potential for this compound, which continues to inspire research and innovation.

Synonyms
Diflumidone
22736-85-2
Diflumidona
Diflumidonum
E96467495S
DTXSID90177275
RefChem:133582
DTXCID2099766
N-(3-Benzoylphenyl)-1,1-difluoromethanesulfonamide
R807
Diflumidonum [INN-Latin]
Diflumidone [INN:BAN]
R 807 (Pharmaceutical)
Diflumidona [INN-Spanish]
BRN 2151784
R 807
3'-Benzoyl-1,1-difluoro-methanesulfonanilide
Methanesulfonanilide, 3'-benzoyl-1,1-difluoro-
UNII-E96467495S
Methanesulfonamide, N-(3-benzoylphenyl)-1,1-difluoro-
DIFLUMIDONE [INN]
SCHEMBL43413
orb1707378
CHEMBL2110671
JLBDOSAQLCZTSX-UHFFFAOYSA-N
XAA73685
AKOS040741640
DA-72761
HY-100139
CS-0018128
3'-BENZOYL-1,1-DIFLUOROMETHANESULFONANILIDE
Q27277039
METHANESULFONAMIDE, N-(3-BENZOYLPHENYL)-1,1-DIFLUORO