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N-(3-Bromophenyl)-2-iodoacetamide

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Identification
Molecular formula
C8H7BrINO
CAS number
771581-97-1
IUPAC name
N-(3-bromophenyl)-2-iodo-acetamide
State
State

At room temperature, N-(3-Bromophenyl)-2-iodoacetamide is in a solid state.

Melting point (Celsius)
145.00
Melting point (Kelvin)
418.15
Boiling point (Celsius)
335.00
Boiling point (Kelvin)
608.15
General information
Molecular weight
342.96g/mol
Molar mass
342.9800g/mol
Density
2.1000g/cm3
Appearence

This compound is typically a crystalline solid. It can form distinct crystals or amorphous powder, depending on the method of preparation. The color can vary from white to off-white.

Comment on solubility

Solubility of N-(3-bromophenyl)-2-iodo-acetamide

N-(3-bromophenyl)-2-iodo-acetamide is a compound that exhibits interesting solubility properties influenced by its molecular structure. The solubility of this compound can be characterized as follows:

  • Polar Characteristics: The presence of the amide functional group contributes to some degree of polarity, which generally facilitates interactions with polar solvents such as water.
  • Hydrophobic Regions: The aromatic bromophenyl and iodo groups introduce significant hydrophobic characteristics, which can lead to lower solubility in polar solvents.
  • Solvent Dependence: Solubility may vary significantly between different solvents. For example, this compound is more likely to be soluble in organic solvents such as dichloromethane or dimethyl sulfoxide (DMSO).
  • Temperature Influence: Like many organic compounds, solubility may increase with temperature, making it easier to dissolve in suitable solvents at elevated temperatures.

To summarize, N-(3-bromophenyl)-2-iodo-acetamide demonstrates a nuanced solubility profile that reflects its structural features. As always in chemistry, understanding the context of solubility is crucial when selecting solvents for various applications or reactions.

Interesting facts

N-(3-bromophenyl)-2-iodo-acetamide: A Fascinating Compound

N-(3-bromophenyl)-2-iodo-acetamide, a member of the amide family, showcases intriguing properties and potential applications that make it a topic of interest within both academic and industrial chemistry. This compound can be discussed from various scientific perspectives:

Chemical Structure and Stability

The unique presence of both bromine and iodine atoms in its structure not only makes it a complex molecule but also hints at its potential reactivity and stability. The interactions between heavy halogens such as bromine and iodine can lead to fascinating phenomena, including:

  • Enhanced Reactivity: The bulky nature of these halogens can influence the molecule’s reactivity, allowing it to participate in diverse chemical reactions.
  • Intermolecular Interactions: The halogens may contribute to strong hydrogen bonding or dipole-dipole interactions, significantly impacting the compound's behavior in various environments.

Applications in Organic Synthesis

This compound presents exciting possibilities in synthetic chemistry. Some notable applications include:

  • Pharmaceutical Development: Compounds with halogen substituents are often integral in drug design, enhancing biological activity and modulating pharmacokinetics.
  • Dye Chemistry: The bromophenyl group can serve as a chromophore or assist in creating novel dye molecules for textiles and materials.

Biological Activity

Research into halogenated compounds has identified them as key players in the realm of biological activity. N-(3-bromophenyl)-2-iodo-acetamide may exhibit:

  • Antimicrobial Properties: Several brominated and iodinated compounds are known for their ability to suppress bacterial growth, making them valuable in medical applications.
  • Potential Anticancer Activity: Investigations into structures similar to this compound have suggested the potential for cancer therapeutic applications.

As with many chemical compounds, understanding the characteristics and applications of N-(3-bromophenyl)-2-iodo-acetamide offers an exciting glimpse into the world of organic chemistry, highlighting how even a single molecule can influence various scientific fields. Whether utilized in pharmaceuticals or materials science, its multifaceted nature underscores the significance of halogenated amides in advancing chemical research.

Synonyms
ACETANILIDE, 3'-BROMO-2-IODO-
17641-05-3
3'-Bromo-2-iodoacetanilide
BRN 2831843
DTXSID70170128
AKOS014116756