Skip to main content

N-(3-bromophenyl)-3-methyl-imidazo[4,5-g]quinazolin-8-amine

ADVERTISEMENT
Identification
Molecular formula
C17H13BrN4
CAS number
NA
IUPAC name
N-(3-bromophenyl)-3-methyl-imidazo[4,5-g]quinazolin-8-amine
State
State

This chemical compound exists as a solid at room temperature. It is relatively stable but should be handled carefully to prevent moisture absorption or degradation under unfavorable conditions.

Melting point (Celsius)
235.00
Melting point (Kelvin)
508.15
Boiling point (Celsius)
472.00
Boiling point (Kelvin)
745.15
General information
Molecular weight
348.22g/mol
Molar mass
348.1850g/mol
Density
1.5800g/cm3
Appearence

The compound is typically a solid. The appearance of the compound often varies from pale yellow to off-white crystalline powder depending on purity and specific batch conditions.

Comment on solubility

Solubility of N-(3-bromophenyl)-3-methyl-imidazo[4,5-g]quinazolin-8-amine

The solubility of the compound N-(3-bromophenyl)-3-methyl-imidazo[4,5-g]quinazolin-8-amine (C17H13BrN4) exhibits characteristics typical of many organic heterocycles. Understanding its solubility is essential for various applications, particularly in pharmaceuticals and material science.

Key Factors Affecting Solubility

  • Polarity: The presence of aromatic rings and nitrogen atoms can influence the overall polarity of the molecule, affecting its ability to dissolve in polar or non-polar solvents.
  • Hydrogen Bonding: The amine functional group may participate in hydrogen bonding, enhancing solubility in polar solvents such as water.
  • Salts and Solvents: The compound's solubility may significantly change when forming salts with acids or bases. Solubility in organic solvents like DMSO or ethanol may also be high.

In practical terms, it is often noted that:

  • The compound may show moderate solubility in DMSO and methanol.
  • It may have low solubility in water at room temperature, which is a typical characteristic of many organic compounds with significant hydrophobic features.

Thus, when working with N-(3-bromophenyl)-3-methyl-imidazo[4,5-g]quinazolin-8-amine, one should always consider the solvent system being used for dissolution to optimize its utilization effectively.

Interesting facts

Interesting Facts about N-(3-bromophenyl)-3-methyl-imidazo[4,5-g]quinazolin-8-amine

N-(3-bromophenyl)-3-methyl-imidazo[4,5-g]quinazolin-8-amine is a fascinating compound with significant implications in the field of medicinal chemistry. Here are some key points to consider:

  • Diverse Applications: This compound belongs to a class of molecules known as imidazoquinazolines, which are extensively investigated for their potential as therapeutic agents. Their structures make them suitable candidates for drug development, particularly in oncology.
  • Mechanistic Insights: The unique arrangement of nitrogen heterocycles in the imidazoquinazoline framework allows for profound interactions with biological targets, such as enzymes and receptors involved in cell signaling pathways. This interaction can influence various disease processes.
  • Significance of Bromine: The presence of bromine in the phenyl group introduces *specificity and variability* to the compound’s biochemical interactions. Substituted bromophenyl groups often enhance the lipophilicity and can modulate the pharmacokinetic properties of the drug.
  • Research Potential: Studies have shown that compounds like N-(3-bromophenyl)-3-methyl-imidazo[4,5-g]quinazolin-8-amine can serve as lead compounds for further modification to optimize activity and reduce toxicity. Scientists often modify structures to create analogs that can lead to better therapeutic outcomes.
  • Emerging Trends: With the rise of personalized medicine, compounds such as this one are becoming increasingly relevant as they can be tailored to address specific molecular targets related to individual patients’ conditions.

In summary, N-(3-bromophenyl)-3-methyl-imidazo[4,5-g]quinazolin-8-amine stands at the intersection of research and application in medicinal chemistry, demonstrating the potential for innovative therapeutic strategies through its unique structural properties.

Synonyms
bpiq-i
174709-30-9
N-(3-bromophenyl)-3-methylimidazo[4,5-g]quinazolin-8-amine
N-(3-bromophenyl)-3-methyl-3H-imidazo[4,5-g]quinazolin-8-amine
3H-Imidazo[4,5-g]quinazolin-8-amine, N-(3-bromophenyl)-3-methyl-
8-[(3-Bromophenyl)amino]-3-methyl-3H-imidazo[4,5-g]-quinazoline
Imidazoquinazoline deriv. 12
BDBM3574
CHEMBL174426
GTPL5939
SCHEMBL17931472
DTXSID60274366
HMS3229C05
EX-A10920
HSCI1_000090
AKOS025394452
CCG-206740
SDCCGSBI-0086664.P003
DA-71690
HY-112405
CS-0045458
BRD-K72211743-001-01-1
Q27075461