Interesting facts
Interesting Facts about N-(3-bromophenyl)-6,7-dimethoxy-quinazolin-4-amine
N-(3-bromophenyl)-6,7-dimethoxy-quinazolin-4-amine is an intriguing chemical compound that belongs to the quinazolinamine class, known for its pharmaceutical potential and diverse biological activities. Here are some captivating insights into this compound:
- Structure Complexity: The compound features a quinazoline core, which is a bicyclic structure that consists of a benzene ring fused to a pyrimidine ring. This unique structure provides a platform for various substitutions that can significantly influence its biological activity.
- Biological Significance: Compounds that share a similar scaffold to N-(3-bromophenyl)-6,7-dimethoxy-quinazolin-4-amine have been studied for their potential in treating a variety of diseases, including cancers and inflammatory disorders.
- Substituent Influence: The presence of the 3-bromophenyl and dimethoxy groups is of particular interest. The bromine atom can enhance binding interactions with biological targets, while the dimethoxy groups can affect solubility and pharmacokinetics.
- Synthetic Pathways: The synthesis of quinazolinamines often involves multi-step reactions that may include reactions like cyclization, coupling, or functionalization, making the development of this compound a fascinating study in synthetic organic chemistry.
- Keywords in Research: Researchers often emphasize the terms "antitumor," "antimicrobial," and "cognitive disorder modulation" in studies involving similar quinazoline derivatives—a reflection of their broad therapeutic applications.
In summary, N-(3-bromophenyl)-6,7-dimethoxy-quinazolin-4-amine presents a rich field for exploration in medicinal chemistry, with its complex structure and diverse potential benefits to human health. As the quest for new pharmaceutical agents continues, compounds like this one are at the forefront of modern medicinal research.
Synonyms
153436-54-5
N-(3-bromophenyl)-6,7-dimethoxyquinazolin-4-amine
PD153035
PD-153035
pd 153035
4-(3-BROMOANILINO)-6,7-DIMETHOXYQUINAZOLINE
WHI-P-79
NSC-669364
AG-1517
SU-5271
4-(3-bromophenylamino)-6,7-dimethoxyquinazoline
AG 1517
SU 5271
(3-Bromophenyl)(6,7-dimethoxyquinazolin-4-yl)amine
GI 230329A
TC62B68RSL
CHEMBL29197
4-QUINAZOLINAMINE, N-(3-BROMOPHENYL)-6,7-DIMETHOXY-
CHEBI:91076
DTXSID80165328
4-[(3-Bromophenyl)amino]-6,7-dimethoxyquinazoline
4-((3-bromophenyl)amino)-6,7-dimethoxyquinazoline
Tyrphostin AG 1517
ZM 252868
UNII-TC62B68RSL
SR-01000597835
MFCD00934896
N-(3-BROMOPHENYL)-6,7-DIMETHOXY-4-QUINAZOLINAMINE
Tocris-1037
SCHEMBL9423
AG-1517 HCl
BDBM3032
DTXCID5087819
LSPANGZZENHZNJ-UHFFFAOYSA-
LSPANGZZENHZNJ-UHFFFAOYSA-N
BCP00569
EX-A1235
HSCI1_000100
s6546
AKOS003676410
BCP9001062
CS-0143
DS-1673
SDCCGSBI-0634834.P002
NCGC00024956-01
NCGC00024956-02
NCGC00024956-04
NCGC00024956-18
NCGC00024956-19
AC-32897
HY-14346
DB-028592
K00043
PD 153035(AG-1517)?
SR-01000597835-2
BRD-K26603252-001-01-9
BRD-K26603252-003-04-9
Q27163047
PD 153035 - CAS 153436-54-5
PD153035;SU-5271; AG1517; ZM 252868
PD 153035; SU 5271; 4-[(3-Bromophenyl)amino]-6,7-dimethoxyquinazoline
InChI=1/C16H14BrN3O2/c1-21-14-7-12-13(8-15(14)22-2)18-9-19-16(12)20-11-5-3-4-10(17)6-11/h3-9H,1-2H3,(H,18,19,20)
Solubility of N-(3-bromophenyl)-6,7-dimethoxy-quinazolin-4-amine
N-(3-bromophenyl)-6,7-dimethoxy-quinazolin-4-amine, with the chemical formula C16H14BrN3O2, exhibits unique solubility characteristics that are important for its application in various fields. The solubility of this compound can be influenced by several factors:
As a result, this compound is mainly suited for formulations where non-aqueous solvents are utilized. As a general observation, the solubility of quinazoline derivatives like this one can often be improved by modifying their chemical structure or adjusting the formulation conditions.
Understanding these solubility characteristics is crucial for synthesizing effective pharmaceutical formulations, as enhanced solubility can lead to improved bioavailability and therapeutic efficacy.