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3-bromo-N-[(2-chloroethyl)-2-chloroethyl]benzylamine

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Identification
Molecular formula
C11H14BrCl2N
CAS number
132344-20-2
IUPAC name
N-[(3-bromophenyl)methyl]-2-chloro-N-(2-chloroethyl)ethanamine
State
State

The compound is in a liquid state at room temperature around 25°C (77°F). It has a faint, characteristic amine-like odor.

Melting point (Celsius)
-10.50
Melting point (Kelvin)
262.65
Boiling point (Celsius)
303.40
Boiling point (Kelvin)
576.55
General information
Molecular weight
294.55g/mol
Molar mass
294.5530g/mol
Density
1.3683g/cm3
Appearence

This compound typically appears as a colorless to pale yellow liquid. It may look clear but can become slightly cloudy upon standing.

Comment on solubility

Solubility Characteristics of N-[(3-bromophenyl)methyl]-2-chloro-N-(2-chloroethyl)ethanamine

N-[(3-bromophenyl)methyl]-2-chloro-N-(2-chloroethyl)ethanamine is a complex compound with unique solubility properties influenced by its molecular structure. Understanding its solubility is crucial for applications in pharmaceuticals and chemical research. Here are some key points to consider:

  • Polarity: The presence of both bromine and chlorine atoms increases the polarity of the molecule, which can enhance solubility in polar solvents such as water.
  • Hydrophobic Interactions: The aromatic ring structure may lead to hydrophobic interactions, potentially decreasing solubility in non-polar solvents.
  • Solvent Dependency: The solubility of this compound is likely to vary significantly in different solvents. It may be more soluble in organic solvents like ethanol and DMSO than in water.
  • Temperature Effects: Increased temperature generally increases solubility for most compounds; however, the specific behavior of this compound at various temperatures would require experimental validation.

In summary, the solubility of N-[(3-bromophenyl)methyl]-2-chloro-N-(2-chloroethyl)ethanamine is influenced by its unique chemical structure, overall polarity, and the nature of the solvent. Future studies may focus on quantitative solubility measurements to enhance practical applications in chemical formulations.

Interesting facts

Interesting Facts about N-[(3-bromophenyl)methyl]-2-chloro-N-(2-chloroethyl)ethanamine

N-[(3-bromophenyl)methyl]-2-chloro-N-(2-chloroethyl)ethanamine is a fascinating compound that has garnered attention in the field of medicinal chemistry. Below are some intriguing facts regarding this compound:

  • Pharmacological Potential: This compound exhibits potential as a pharmacophore in drug development, especially in designing agents that target specific diseases due to its unique structural variations.
  • Synthetic Pathways: The synthesis of this compound often involves the halogenation of aromatic rings, which is a common strategy in organic chemistry for introducing functional groups that enhance biological activity.
  • Biological Activity: Compounds similar to N-[(3-bromophenyl)methyl]-2-chloro-N-(2-chloroethyl)ethanamine have been studied for their ability to interact with neurotransmitter systems, potentially influencing mood and cognition.
  • Structure-Activity Relationship (SAR): This compound's structural elements, including the bromophenyl and chloroethyl groups, are critical for understanding SAR, leading to optimized compounds with better efficacy and selectivity in pharmacological testing.
  • Environmental and Safety Considerations: Due to the presence of halogen atoms, especially bromine and chlorine, caution is advised with regard to the environmental impact and safe handling of this compound during research and application.

Moreover, the study of compounds like this one provides invaluable insights into the complex interplay between chemistry and biology. As scientists continue to explore the potential applications of such compounds, they pave the way for innovations in therapeutics and pharmaceutical developments.

Synonyms
2361-59-3
N,N-Bis(2-chloroethyl)-m-bromobenzylamine
N-[(3-bromophenyl)methyl]-2-chloro-N-(2-chloroethyl)ethanamine
3-Bromo-N,N-bis(2-chloroethyl)benzenemethanamine
Benzenemethanamine, 3-bromo-N,N-bis(2-chloroethyl)-
m-Bromo-dcba
BRN 2841930
m-Bromo-di-(2-chloroethyl)-benzylamine
BENZYLAMINE, N,N-BIS(2-CHLOROETHYL)-m-BROMO-
QTY5S6353V
DTXSID60178274
Benzenemethanamine, 3-bromo-N,N-bis(2-chloroethyl)- (9CI)
m-Bromo-bis(2-chloroethyl)benzylamine
A1-06051
Bromo-N,N-bis(2-chloroethyl)benzenemethanamine, 3-