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N-(3-Chloro-2-methylphenyl)-N,N-dimethylformamidine

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Identification
Molecular formula
C10H13ClN2
CAS number
42006-56-8
IUPAC name
N'-(3-chloro-2-methyl-phenyl)-N,N-dimethyl-formamidine
State
State

At room temperature, the compound is generally in a solid state.

Melting point (Celsius)
47.00
Melting point (Kelvin)
320.15
Boiling point (Celsius)
300.50
Boiling point (Kelvin)
573.65
General information
Molecular weight
196.68g/mol
Molar mass
196.6760g/mol
Density
1.0630g/cm3
Appearence

The compound tends to appear as a solid crystalline substance, typically exhibiting pale yellow to white colored crystals.

Comment on solubility

Solubility of N'-(3-chloro-2-methyl-phenyl)-N,N-dimethyl-formamidine

N'-(3-chloro-2-methyl-phenyl)-N,N-dimethyl-formamidine, with its complex structure, displays notable solubility characteristics that are essential for various applications. Here are some key points regarding its solubility:

  • Solvent Compatibility: This compound is expected to be more soluble in polar solvents due to the presence of the formamidine functional group, which can engage in hydrogen bonding.
  • Influence of Substituents: The 3-chloro and 2-methyl substituents on the phenyl ring can affect the solubility:
    • The chlorine atom can enhance solubility in organic solvents due to its electronegative nature.
    • The methyl group increases the hydrophobic character, which may reduce solubility in highly polar solvents.
  • Temperature Effect: Like many organic compounds, solubility can increase with temperature, making it easier to dissolve the compound in chosen solvents at elevated temperatures.

In conclusion, while a comprehensive solubility profile requires experimental data, the structural features of N'-(3-chloro-2-methyl-phenyl)-N,N-dimethyl-formamidine suggest a favorable solubility in both polar and non-polar environments, making it a versatile candidate for various chemical applications.

Interesting facts

Interesting Facts about N'-(3-Chloro-2-methyl-phenyl)-N,N-dimethyl-formamidine

N'-(3-chloro-2-methyl-phenyl)-N,N-dimethyl-formamidine is a fascinating compound that plays a significant role in various fields of chemistry and pharmacology. Here are some intriguing insights about this compound:

  • Biological Activity: This compound is often studied for its potential biological activities, including its role as a biological probe in medicinal chemistry. Researchers investigate its effects on various biological targets to understand its mechanism of action.
  • Functional Groups: The presence of the formamidine functional group in this compound enhances its reactivity and potential for hydrogen bonding, which can be crucial in interactions with biological macromolecules.
  • Chlorine Substitution: The 3-chloro substitution on the phenyl ring is particularly interesting. Chlorine atoms can significantly influence the compound's properties, including its lipophilicity and binding affinity to specific targets.
  • Application in Synthesis: This compound can serve as an intermediate in the synthesis of other chemical entities. This makes it valuable in the development of new pharmaceuticals and agrochemicals.
  • Research Potential: Due to its unique structure, N'-(3-chloro-2-methyl-phenyl)-N,N-dimethyl-formamidine continues to be a subject of research, with scientists exploring its potential applications in drug design and development.

Overall, N'-(3-chloro-2-methyl-phenyl)-N,N-dimethyl-formamidine showcases the intricate connections between chemistry and biology, offering numerous possibilities for discovery and innovation in the scientific community. As noted by researchers, "The journey from structure to function is a captivating aspect of medicinal chemistry."

Synonyms
13181-62-9
N'-(3-chloro-2-methylphenyl)-N,N-dimethylmethanimidamide
N/'-(3-Chloro-o-tolyl)-N,N-dimethylformamidine
BRN 2087757
Formamidine, N'-(3-chloro-o-tolyl)-N,N-dimethyl-
N-(3-Chloro-2-methylphenyl)-N,N-dimethylformamidine
FORMAMIDINE, N'-(3-CHLORO-2-METHYLPHENYL)-N,N-DIMETHYL-