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Bicyclo[2.2.1]heptan-2-amine, N-[(3-chloro-4-fluorophenyl)methyl]-1,7,7-trimethyl-

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Identification
Molecular formula
C17H23ClFN
CAS number
208986-40-7
IUPAC name
N-[(3-chloro-4-fluoro-phenyl)methyl]-1,7,7-trimethyl-norbornan-2-amine
State
State

This compound is in a solid state at room temperature, displaying a crystalline form and stable structure. It is typically stable under regular conditions but should be kept away from sources of ignition or extreme temperatures.

Melting point (Celsius)
68.00
Melting point (Kelvin)
341.15
Boiling point (Celsius)
280.00
Boiling point (Kelvin)
553.15
General information
Molecular weight
303.81g/mol
Molar mass
303.8060g/mol
Density
1.1800g/cm3
Appearence

This compound typically appears as a colorless to pale yellow solid. It is known for its crystalline structure and can be slightly odorous depending on the purity of the sample.

Comment on solubility

Solubility Overview

The compound N-[(3-chloro-4-fluoro-phenyl)methyl]-1,7,7-trimethyl-norbornan-2-amine exhibits unique solubility characteristics that influence its behavior in various environments. Understanding these properties is crucial for applications in pharmaceuticals and organic chemistry.

Factors Influencing Solubility

Several factors affect the solubility of this compound:

  • Polarity: The presence of polar functional groups, such as the amine group, enhances solubility in polar solvents.
  • Hydrophobic Regions: The bulky norbornane structure and aromatic ring contribute to hydrophobic interactions, which can diminish solubility in water.
  • Temperature: Increased temperature typically improves solubility for most organic compounds due to enhanced molecular motion.
  • pH Levels: As an amine, the solubility can vary with pH; these variations can affect protonation states and overall solubility in aqueous solutions.

Expected Solubility

In general, one might expect this compound to have:

  • Moderate solubility in polar aprotic solvents like DMSO or DMF.
  • Limited solubility in water, due to its more hydrophobic characteristics.
  • Better solubility in organic solvents, where the non-polar portions of the molecule can interact favorably.

In conclusion, the solubility behavior of N-[(3-chloro-4-fluoro-phenyl)methyl]-1,7,7-trimethyl-norbornan-2-amine can be quite complex, influenced by specific interactions within mixtures. Understanding these nuances is essential for effective application and formulation.

Interesting facts

Interesting Facts About N-[(3-chloro-4-fluoro-phenyl)methyl]-1,7,7-trimethyl-norbornan-2-amine

N-[(3-chloro-4-fluoro-phenyl)methyl]-1,7,7-trimethyl-norbornan-2-amine is a fascinating compound that showcases the diverse nature of organic chemistry. Here are some key aspects that make it noteworthy:

  • Structure and Stability: The compound features a norbornane framework, which is known for its fused bicyclic structure that lends it remarkable stability. This structural integrity allows for interesting interactions with other molecules.
  • Substituents: The presence of fluorine and chlorine atoms (like in 3-chloro-4-fluoro-phenyl) adds interesting electronic properties to the compound, making it a candidate for various chemical reactions and applications.
  • Pharmaceutical Applications: Compounds with such structural characteristics often exhibit biological activity. Research into similar amines has led to significant findings in drug development, particularly in areas targeting neurotransmitter systems.
  • Synthesis Potential: The synthetic routes for compounds with complex substitutions often involve multi-step organic reactions. This layer of complexity presents both challenges and opportunities in synthetic chemistry.
  • Research and Development: Due to its unique features, this compound could inspire research into new materials or drugs, highlighting the significance of exploring various molecular architectures.

As quoted in the literature, "Diversity in molecules leads to diversity in function." This particular compound embodies that ethos, reinforcing the need for ongoing exploration in the realm of organic chemistry.

Overall, N-[(3-chloro-4-fluoro-phenyl)methyl]-1,7,7-trimethyl-norbornan-2-amine stands as a prime example of how intricate molecular designs can lead to rich, unexplored scientific avenues.

Synonyms
AKOS012784369