Skip to main content

N'-(3-chloro-4-methylphenyl)pyridine-4-carboxamidine

ADVERTISEMENT
Identification
Molecular formula
C13H13ClN4
CAS number
81228-57-7
IUPAC name
N'-(3-chloro-4-methyl-phenyl)pyridine-4-carboxamidine
State
State

At room temperature, N'-(3-chloro-4-methylphenyl)pyridine-4-carboxamidine is typically found in a solid state. Its rigidity and crystallinity make it suitable for weighing and various applications in solid form.

Melting point (Celsius)
229.00
Melting point (Kelvin)
502.15
Boiling point (Celsius)
390.00
Boiling point (Kelvin)
663.15
General information
Molecular weight
260.72g/mol
Molar mass
260.7400g/mol
Density
1.3000g/cm3
Appearence

N'-(3-chloro-4-methylphenyl)pyridine-4-carboxamidine appears as a crystalline solid. The coloration can vary from white to slight off-white, and it may exhibit a crystalline powder form depending on the purity and specific manufacturing process.

Comment on solubility

Solubility of N'-(3-chloro-4-methyl-phenyl)pyridine-4-carboxamidine

N'-(3-chloro-4-methyl-phenyl)pyridine-4-carboxamidine, a compound with diverse applications, exhibits specific solubility characteristics that can be critical for its practical use. Understanding these properties can help in selecting appropriate solvents for various applications. Here are some key points regarding its solubility:

  • Polarity: The presence of both a chloro group and a carboxamidine functional group indicates that the compound may have a moderate level of polarity. This often translates to various solubility behaviors in polar and non-polar solvents.
  • Solvent Compatibility: Due to its structure, N'-(3-chloro-4-methyl-phenyl)pyridine-4-carboxamidine is likely to be soluble in:
    • Polar solvents such as water and alcohols,
    • Non-polar solvents may have limited solubility.
  • Temperature Dependence: The solubility could vary significantly with temperature, where higher temperatures typically increase solubility in many solvents.
  • pH Sensitivity: The solubility of carboxamidine derivatives may also be affected by the pH of the solution, making it crucial to consider the ionic state of the compound.

In summary, the solubility of N'-(3-chloro-4-methyl-phenyl)pyridine-4-carboxamidine is a multifaceted aspect that influences its applications. Given its moderate polarity and potential interactions with various solvents, careful consideration should be taken when determining optimal solubility conditions for experimental purposes.

Interesting facts

Interesting Facts about N'-(3-chloro-4-methyl-phenyl)pyridine-4-carboxamidine

N'-(3-chloro-4-methyl-phenyl)pyridine-4-carboxamidine is a fascinating compound that has garnered attention in the field of pharmaceutical chemistry. Here are some intriguing facts:

  • Biological Activity: This compound exhibits significant biological activity, often being studied for its potential as a therapeutic agent. Its structure is conducive to interacting with various biological targets, making it a candidate for drug development.
  • Structural Features: The compound features a pyridine ring, which is a common motif in many drugs due to its stable aromatic nature. The presence of both chloro and methyl groups on the phenyl ring further enhances its reactivity and potential for modification.
  • Versatile Applications: Due to its unique functional groups, N'-(3-chloro-4-methyl-phenyl)pyridine-4-carboxamidine can be utilized in synthesizing other more complex molecules or used in various chemical reactions including coupling and condensation reactions.
  • Scientific Interest: Researchers are particularly interested in how the specific arrangement of atoms in this compound can lead to different biological effects. It is often a subject of study in medicinal chemistry labs focusing on the development of new drugs.
  • Potential Side Effects: As with many bioactive compounds, understanding the side effects is crucial. Ongoing studies aim to clarify the pharmacokinetic and pharmacodynamic properties of this compound, helping to assess its safety profile.

This compound exemplifies the intricate balance between chemistry and biology, leading to exciting possibilities in medicinal applications. As we delve into the intricacies of chemical compounds like N'-(3-chloro-4-methyl-phenyl)pyridine-4-carboxamidine, we uncover the potential for advancements in health and medicine.

Synonyms
N-(3-Chloro-p-tolyl)isonicotinamidine
23564-67-2
BRN 0477386
ISONICOTINAMIDINE, N-(3-CHLORO-p-TOLYL)-
4-Pyridinecarboximidamide, N-(3-chloro-4-methylphenyl)-
DTXSID90178166
RefChem:349656
DTXCID20100657