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Chlorinated amphetamine derivative

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Identification
Molecular formula
C12H18ClN
CAS number
.
IUPAC name
N-(3-chloropropyl)-1-phenyl-propan-2-amine
State
State

At room temperature, the compound is generally in a liquid state. It is not very volatile and may have moderate viscosity due to its oily nature.

Melting point (Celsius)
-70.00
Melting point (Kelvin)
203.15
Boiling point (Celsius)
225.00
Boiling point (Kelvin)
498.15
General information
Molecular weight
215.72g/mol
Molar mass
215.7220g/mol
Density
1.0119g/cm3
Appearence

The compound typically appears as a colorless to pale yellow liquid. It is often oily in texture and may have a faint aromatic odor.

Comment on solubility

Solubility of N-(3-chloropropyl)-1-phenyl-propan-2-amine

The solubility of N-(3-chloropropyl)-1-phenyl-propan-2-amine, commonly referred to as a substituted amine, can vary depending on several factors including the solvent used and temperature. Here’s what you need to know:

  • Polarity: The presence of the amine functional group generally increases solubility in polar solvents such as water. However, the addition of a chloropropyl group may introduce some hydrophobic character.
  • Solvent Compatibility: The compound is likely to be soluble in organic solvents like ethanol, methanol, or acetone due to its overall structure. In contrast, its solubility in water may be limited.
  • Temperature Effects: Generally, an increase in temperature can enhance solubility by providing energy that overcomes intermolecular interactions.

It is important to note that the actual solubility can be quantitatively determined only through experimental data, as specific measurements may reveal varying results across different conditions.

In conclusion, while N-(3-chloropropyl)-1-phenyl-propan-2-amine may show solubility in various solvents, its precise solubility will depend on the balance between polar and non-polar characteristics contributed by its functional groups.

Interesting facts

Interesting Facts about N-(3-chloropropyl)-1-phenyl-propan-2-amine

N-(3-chloropropyl)-1-phenyl-propan-2-amine, often abbreviated to a simpler structure depending on its context, is a fascinating compound that belongs to the class of amines. This compound has captured the interest of scientists and researchers for several reasons:

  • Chemical Structure: The unique composition features a chloropropyl group attached to a phenyl ring, making it a significant subject in organic synthesis and medicinal chemistry.
  • Potential Applications: Compounds with similar structures are often explored for their potential therapeutic effects, particularly in treating various neurological disorders. Some research suggests that modifications to the structure could enhance receptor binding in the central nervous system.
  • Synthesis Routes: The synthesis of N-(3-chloropropyl)-1-phenyl-propan-2-amine can be achieved through multiple pathways, allowing chemists to experiment with different reaction conditions and catalysts to improve yield and purity.
  • Safety Considerations: Like many amines, this compound must be handled with care due to its potential to be toxic or act as an irritant. Proper lab safety protocols are essential when working with such compounds.
  • Research Interest: Ongoing studies focus on understanding its mechanism of action and exploring how structural variations affect biological activity, paving the way for the development of new pharmaceuticals.

As it stands, N-(3-chloropropyl)-1-phenyl-propan-2-amine is part of a diverse array of chemical compounds with promising applications. The exploration of its properties contributes to the broader field of medicinal chemistry, heralding advancements in drug discovery and development.

Synonyms
MEFENOREX
Mefenorex [INN]
17243-57-1
Mefenorexum
Mefenorexum [INN-Latin]
EINECS 241-279-0
Mefenorex (DCF)
N-(3-Chloropropyl)-alpha-methylbenzeneethanamine
BRN 2833093
DTXSID6057665
K98M4N387W
MEFENOREX [MI]
MEFENOREX [WHO-DD]
Phenethylamine, N-(3-chloropropyl)-.alpha.-methyl-
DTXCID7031454
N-(3-Chloropropyl)-alpha-methylphenethylamine
n-(3-chloropropyl)-.alpha.-methylphenethylamine
Phenethylamine, N-(3-chloropropyl)-alpha-methyl-
Benzeneethanamine, N-(3-chloropropyl)-alpha-methyl-
Mefenorexum (INN-Latin)
(3-chloropropyl)(1-phenylpropan-2-yl)amine
chloropropylamphetamine
BENZENEETHANAMINE, N-(3-CHLOROPROPYL)-.ALPHA.-METHYL
BENZENEETHANAMINE, N-(3-CHLOROPROPYL)-ALPHA-METHYL
Benzeneethanamine, N-(3-chloropropyl)-alpha-methyl-(9CI)
241-279-0
(+)-Mefenorex
(-)-Mefenorex
Mefenorex, (+)-
Mefenorex, (-)-
7FT4O2NC8G
DEA No. 1580
85052999IT
111051-41-3
111051-42-4
N-(3-chloropropyl)-1-phenylpropan-2-amine
UNII-K98M4N387W
UNII-7FT4O2NC8G
SCHEMBL149720
Benzeneethanamine, N-(3-chloropropyl)-.alpha.-methyl-
CHEMBL2110962
CHEBI:134883
UNII-85052999IT
Tox21_113684
DB13852
NCGC00249908-01
CAS-17243-57-1
NS00008474
D07891
3-Chloro-N-(1-methyl-2-phenylethyl)-1-propanamine #
Q10579342
Benzeneethanamine, N-(3-chloropropyl)-alpha-methyl-, (+)-
Benzeneethanamine, N-(3-chloropropyl)-alpha-methyl-, (-)-
BENZENEETHANAMINE, N-(3-CHLOROPROPYL)-.ALPHA.-METHYL-, (+)-
BENZENEETHANAMINE, N-(3-CHLOROPROPYL)-.ALPHA.-METHYL-, (-)-