Skip to main content

Chlorphentermine hydrochloride

ADVERTISEMENT
Identification
Molecular formula
C12H17ClN.HCl
CAS number
4611-66-3
IUPAC name
N-(3-chloropropyl)-1-phenyl-propan-2-amine;hydrochloride
State
State

At room temperature, chlorphentermine hydrochloride is in a solid state due to its crystalline form. It is not typically volatile under normal conditions.

Melting point (Celsius)
175.00
Melting point (Kelvin)
448.15
Boiling point (Celsius)
170.00
Boiling point (Kelvin)
443.15
General information
Molecular weight
227.19g/mol
Molar mass
227.1860g/mol
Density
1.0425g/cm3
Appearence

Chlorphentermine hydrochloride is typically a white crystalline powder. It may sometimes appear as an off-white powder due to impurities or variations in synthesis processes.

Comment on solubility

Solubility of N-(3-chloropropyl)-1-phenyl-propan-2-amine;hydrochloride

N-(3-chloropropyl)-1-phenyl-propan-2-amine;hydrochloride is a compound with varying solubility characteristics that can depend on several factors:

  • Solvent Type: This compound is generally soluble in polar solvents, particularly water and alcohols, due to the presence of the hydrochloride group. However, it may have limited solubility in non-polar solvents.
  • pH Dependency: The solubility may vary with pH, as the protonation state of the amine can affect its interaction with water molecules.
  • Temperature Influence: Like many other hydrochlorides, solubility increases with temperature. Warmer solvents can enhance the dissolution process.
  • Crystalline Structure: The purity and crystallinity of the compound can also influence its solubility. More crystalline forms may be less soluble compared to their amorphous counterparts.

In general, when analyzing solubility, it's essential to consider multiple aspects to fully understand how and where N-(3-chloropropyl)-1-phenyl-propan-2-amine;hydrochloride will dissolve. The interplay of these factors often leads to unique solubility behaviors that are crucial in both laboratory and practical applications.

Interesting facts

Exploring N-(3-Chloropropyl)-1-phenyl-propan-2-amine Hydrochloride

N-(3-chloropropyl)-1-phenyl-propan-2-amine hydrochloride, often referenced in research and academic discussions, brings intriguing insights into organic chemistry and medicinal applications. This compound belongs to the class of amines, which play a vital role in various biochemical processes.

Notable Characteristics

  • Pharmacological Interest: This compound is studied for its potential effects on the central nervous system and might exhibit stimulant properties, drawing interest from pharmacologists and chemists alike.
  • Structural Complexity: Featuring both a phenyl group and a chloropropyl substituent, its structure allows for diverse reactivity and interaction pathways, making it an excellent candidate for research in synthesis.
  • Substituent Influence: The presence of the chlorine atom is significant as it can modify the compound's lipophilicity, which in turn may affect its biological activity.
  • Diverse Applications: Beyond its potential medicinal uses, derivatives of this compound could lead to new materials with unique properties in polymer science or catalysis.

The Synthesis Journey

The synthesis of N-(3-chloropropyl)-1-phenyl-propan-2-amine hydrochloride typically involves several steps, integrating various chemical techniques. Some synthetic strategies include:

  1. Utilization of amine precursors for forming the core structure.
  2. Introductions of the chloropropyl chain via nucleophilic substitution reactions.
  3. Crystallization processes to obtain the hydrochloride salt for purification and increased stability.

As researchers dive deeper into the study of this compound, they continue to uncover its complex behavior and various applications, advancing both medicinal chemistry and our understanding of amine compounds. The ongoing exploration of N-(3-chloropropyl)-1-phenyl-propan-2-amine hydrochloride underscores the dynamic nature of chemical research and its potential impact on pharmaceutical development.

Synonyms
Mefenorex hydrochloride
Doracil
Rondimen
Mefenorex HCl
5586-87-8
Ro 4-5282
Mefenorex hydrochloride [USAN]
N-Chloropropylamphetamine hydrochloride
EINECS 226-985-9
MEFENOREX HYDROCHLDRIDE
NSC 133749
NSC-133749
UNII-6X1N18AU15
R 4-5282
6X1N18AU15
RO-4-5282
Mefenorex hydrochloride (USAN)
N-(3-Chlorpropyl)-1-methyl-2-phenyl-aethylamin-hydrochlorid
N-(3-Chlorpropyl)-1-methyl-2-phenyl-aethylamin-hydrochlorid [German]
MEFENOREX HYDROCHLORIDE [MI]
MEFENOREX HYDROCHLORIDE [MART.]
MEFENOREX HYDROCHLORIDE [WHO-DD]
Phenethylamine, N-(3-chloropropyl)-alpha-methyl-, hydrochloride
MEFENOREX HYDROCHLORIDE (MART.)
(+-)-MEFENOREX HYDROCHLORIDE
MEFENOREX HYDROCHLORIDE, (+-)-
226-985-9
Pondinil
Mefenorex (hydrochloride)
N-(3-Chloropropyl)-alpha-methylphenethylamine hydrochloride
DEA No. 1580
Incital
SCHEMBL122442
CHEMBL2106838
N-(3-chloropropyl)-1-phenylpropan-2-amine;hydrochloride
WLN: G3MY1&1R &GH
Benzeneethanamine, N-(3-chloropropyl)-alpha-methyl-, hydrochloride
HY-U00115
NSC133749
AKOS027327040
(+/-)-MEFENOREX HYDROCHLORIDE
CS-7152
MEFENOREX HYDROCHLORIDE, (+/-)-
NS00081152
D04893
Q27265651
N-(3-Chloropropyl)-.alpha.-methylphenethylamine hydrochloride