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Lidocaine

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Identification
Molecular formula
C14H22N2O
CAS number
137-58-6
IUPAC name
N-[3-(diethylamino)propyl]-N-(2,6-dimethylphenyl)-2-phenyl-acetamide
State
State

At room temperature, lidocaine is in the form of a crystalline solid.

Melting point (Celsius)
68.00
Melting point (Kelvin)
341.15
Boiling point (Celsius)
180.00
Boiling point (Kelvin)
453.15
General information
Molecular weight
234.34g/mol
Molar mass
234.3430g/mol
Density
1.0260g/cm3
Appearence

Lidocaine appears as a white to slightly yellow crystalline powder. It is typically odorless and has a slightly bitter taste.

Comment on solubility

Solubility of N-[3-(diethylamino)propyl]-N-(2,6-dimethylphenyl)-2-phenyl-acetamide

The solubility of N-[3-(diethylamino)propyl]-N-(2,6-dimethylphenyl)-2-phenyl-acetamide can be quite intriguing. This compound, characterized by its relatively complex structure, demonstrates a unique solubility profile:

  • Solvent Dependency: The solubility can vary significantly depending on the solvent used. Common solvents include:
    • Water
    • Organic solvents (such as ethanol, methanol, and dimethyl sulfoxide)
  • Functional Groups: The presence of both polar and nonpolar groups in the compound can influence its ability to dissolve. For instance:
    • The diethylamino group may enhance solubility in polar solvents.
    • The phenyl groups may contribute to lower solubility in water due to hydrophobic interactions.
  • Concentration Effects: At higher concentrations, precipitation may occur, indicating limited solubility. Testing should be conducted to determine specific solubility limits.

As a rule of thumb, compounds with similar polarities tend to dissolve in one another. Therefore, understanding the polarity of this particular compound relative to the solvents available is essential for predicting solubility behaviors.

In conclusion, the solubility of N-[3-(diethylamino)propyl]-N-(2,6-dimethylphenyl)-2-phenyl-acetamide is a nuanced topic that requires consideration of multiple factors, making it essential for researchers and chemists to conduct thorough solubility testing.

Interesting facts

Interesting Facts About N-[3-(diethylamino)propyl]-N-(2,6-dimethylphenyl)-2-phenyl-acetamide

N-[3-(diethylamino)propyl]-N-(2,6-dimethylphenyl)-2-phenyl-acetamide, commonly referred to in scientific circles for its intriguing structural properties, is a notable compound in medicinal chemistry. This compound showcases a unique fusion of functionalities that provide a wealth of opportunities for research and application.

Key Characteristics

  • Pharmacological Importance: This compound is often examined for its potential as a therapeutic agent and its influence on various biological targets.
  • Diverse Applications: The structural design allows it to be explored for uses ranging from analgesics to CNS-active agents.
  • Functional Groups: The presence of both a diethylamino moiety and acetamide elements enhances its pharmacokinetic properties, impacting how the body absorbs, distributes, metabolizes, and excretes the compound.

One of the compelling aspects of this compound lies in its dual amine structure, which could lead to interesting interactions within biological systems. As noted by some researchers, "the interplay between steric and electronic properties within the molecule could significantly influence its binding affinity to various receptors."

Additionally, the two phenyl groups present in the structure can offer substantial hydrophobic interaction capabilities, making it relevant in the context of drug design.

Future Directions

  • Investigational Studies: Ongoing research seeks to unveil more about its mechanism of action and potential therapeutic applications.
  • Structure-Activity Relationship: Understanding how modifications to various parts of the molecule affect efficacy and side effects is crucial for its development.

In conclusion, N-[3-(diethylamino)propyl]-N-(2,6-dimethylphenyl)-2-phenyl-acetamide represents a fascinating example of how structural complexity can lead to rich pharmacological profiles, inviting chemists and pharmacologists alike to delve deeper into its potential.

Synonyms
SA 105
18109-55-2
BRN 2822394
ACETANILIDE, N-(3-(DIETHYLAMINO)PROPYL)-2',6'-DIMETHYL-2-PHENYL-
DTXSID10171073
N-(3-(Diethylamino)propyl)-2',6'-dimethyl-2-phenylacetanilide
DTXCID4093564
ACETANILIDE,N-(3-(DIETHYLAMINO)PROPYL)-2,6-DIMETHYL-2-PHENYL-
SCHEMBL29390506