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Lidocaine

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Identification
Molecular formula
C14H22N2O
CAS number
137-58-6
IUPAC name
N-[3-(diethylamino)propyl]-N-(2,6-dimethylphenyl)-3-phenyl-prop-2-enamide
State
State

At room temperature, Lidocaine is in a solid state. It is often found in pharmaceutical forms such as creams, gels, or as an injectable solution.

Melting point (Celsius)
66.00
Melting point (Kelvin)
339.20
Boiling point (Celsius)
350.80
Boiling point (Kelvin)
623.80
General information
Molecular weight
234.34g/mol
Molar mass
234.3420g/mol
Density
1.0260g/cm3
Appearence

Lidocaine appears as a white to off-white crystalline powder. It is nearly odorless and has a slightly bitter taste. It is often used in its hydrochloride form, which is highly soluble in water.

Comment on solubility

Solubility of N-[3-(diethylamino)propyl]-N-(2,6-dimethylphenyl)-3-phenyl-prop-2-enamide

The solubility of N-[3-(diethylamino)propyl]-N-(2,6-dimethylphenyl)-3-phenyl-prop-2-enamide is influenced by several factors due to its complex structure. This compound is likely to exhibit moderate solubility characteristics due to the presence of both hydrophilic and hydrophobic groups within its molecular framework. Here are a few key points regarding its solubility:

  • Polarities: The diethylamino group adds a polar component, which potentially enhances solubility in polar solvents.
  • Nonpolar Characteristics: The phenyl groups and dimethyl substituents contribute to the hydrophobic nature of the compound, suggesting limited solubility in water.
  • Solvent Interactions: The solubility is likely better in organic solvents such as ethanol, acetone, or dimethyl sulfoxide (DMSO).

Overall, while this compound may dissolve effectively in certain organic media, its solubility in water could be minimal. This dual character necessitates careful consideration when evaluating its applications in various chemical and biological contexts.

Interesting facts

Interesting Facts about N-[3-(diethylamino)propyl]-N-(2,6-dimethylphenyl)-3-phenyl-prop-2-enamide

N-[3-(diethylamino)propyl]-N-(2,6-dimethylphenyl)-3-phenyl-prop-2-enamide is a compound that showcases the fascinating diversity of nitrogen-containing organic molecules. Here are some intriguing aspects of this compound:

  • Structure Complexity: This compound features a complex structure with multiple functional groups, including an amide and an alkenyl unit. Its intricate arrangement leads to a variety of potential reactivity and interaction patterns, making it a valuable subject for synthetic and medicinal chemistry.
  • Biological Relevance: Compounds with structures similar to that of N-[3-(diethylamino)propyl]-N-(2,6-dimethylphenyl)-3-phenyl-prop-2-enamide often exhibit significant biological activity. This includes potential applications in drug discovery, particularly in targeting specific receptors or enzymes in the body.
  • Amides in Chemistry: The amide functional group, central to this compound, is not only prevalent in nature (as seen in proteins) but also widely utilized in pharmaceuticals for its stability and reactivity. Amides can act as intermediates in numerous chemical reactions, enhancing the versatility of compounds like this one.
  • Synthetic Applications: The unique features of N-[3-(diethylamino)propyl]-N-(2,6-dimethylphenyl)-3-phenyl-prop-2-enamide make it a potential target for various synthetic routes in organic chemistry. Researchers can explore methods for its synthesis that improve efficiency and yield.
  • Potential for New Discoveries: As a compound that combines amine and amide functionalities, it holds promise for discovering new chemical properties or reactions, leading to innovations in materials science, such as in the development of polymers or catalysts.

In summary, N-[3-(diethylamino)propyl]-N-(2,6-dimethylphenyl)-3-phenyl-prop-2-enamide serves as a remarkable example of the interplay between structure and function in organic chemistry. Its potential applications in pharmaceuticals and materials science make it an exciting molecule for ongoing research and exploration.