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Clonazolam

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Identification
Molecular formula
C18H12ClN5O3
CAS number
33887-02-4
IUPAC name
N-[3-(dimethylamino)propyl]-2-(4-oxo-2-phenyl-chromen-7-yl)oxy-acetamide
State
State

At room temperature, Clonazolam is typically in a solid state. It is usually handled as a powder or pressed into tablet form.

Melting point (Celsius)
95.00
Melting point (Kelvin)
368.00
Boiling point (Celsius)
416.00
Boiling point (Kelvin)
689.00
General information
Molecular weight
353.79g/mol
Molar mass
353.7870g/mol
Density
1.3205g/cm3
Appearence

Clonazolam is typically found as a white or off-white crystalline powder. It may appear in other physical forms such as pellets or tablets for research purposes, but the pure compound is crystalline.

Comment on solubility

Solubility of N-[3-(dimethylamino)propyl]-2-(4-oxo-2-phenyl-chromen-7-yl)oxy-acetamide

The solubility of N-[3-(dimethylamino)propyl]-2-(4-oxo-2-phenyl-chromen-7-yl)oxy-acetamide can be influenced by several factors, notably its chemical structure and functional groups. This compound contains both hydrophilic (water-attracting) and hydrophobic (water-repelling) characteristics, which can lead to varying solubility in different solvents.

  • Solvent Types:
    • Polar Solvents: This compound may exhibit some solubility in polar solvents such as water and alcohols due to the presence of the amide functional group, which can engage in hydrogen bonding.
    • Non-Polar Solvents: Conversely, it is likely to be more soluble in non-polar solvents like chloroform or hexane given the hydrophobic components of its structure.
  • Temperature Influence:

    Generally, an increase in temperature can enhance the solubility of solid compounds in solvents, allowing for better dissolution of N-[3-(dimethylamino)propyl]-2-(4-oxo-2-phenyl-chromen-7-yl)oxy-acetamide in certain conditions.

  • Concentration Effects:

    As concentration increases, the solubility can also be affected. This compounds interactions may lead to saturation at certain levels, leading to potential precipitation if the solution exceeds its solubility limit.

In summary, the solubility of N-[3-(dimethylamino)propyl]-2-(4-oxo-2-phenyl-chromen-7-yl)oxy-acetamide strikes a balance between its hydrophilic and hydrophobic features, making it an intriguing compound in terms of solubility behavior in various solvents.

Interesting facts

Interesting Facts about N-[3-(dimethylamino)propyl]-2-(4-oxo-2-phenyl-chromen-7-yl)oxy-acetamide

N-[3-(dimethylamino)propyl]-2-(4-oxo-2-phenyl-chromen-7-yl)oxy-acetamide, often abbreviated in research contexts, is a fascinating compound with numerous applications in the field of medicinal chemistry. Here are some notable aspects:

  • Structure and Functionality: The compound features a unique combination of a chromen-7-yl moiety and an acetamide functional group. This structural diversity contributes to its potential biological activities.
  • Biological Significance: Compounds that contain both chromene and amine derivatives are often explored for their pharmacological properties. This particular compound may exhibit interesting effects on various biological systems, including anti-inflammatory and anticancer activities.
  • Synthetic Pathways: The synthesis of such complex compounds typically involves intricate organic reactions. Chemists have creatively utilized various methods such as quaternization and amide bond formation to produce this compound, showcasing the versatility of organic synthesis techniques.
  • Research Potential: Ongoing studies of N-[3-(dimethylamino)propyl]-2-(4-oxo-2-phenyl-chromen-7-yl)oxy-acetamide are likely to uncover even more about its properties, enhancing our understanding of how structural modifications can lead to variations in biological activity.
  • Interdisciplinary Implications: The compound serves as a bridge between organic chemistry and pharmacology, making it a relevant subject in discussions surrounding drug design and discovery.

As a compound of interest, N-[3-(dimethylamino)propyl]-2-(4-oxo-2-phenyl-chromen-7-yl)oxy-acetamide is poised to contribute to our understanding of complex chemical interactions in biological systems. Its study could unveil new therapeutic agents that leverage the therapeutic potential embedded in its molecular structure.

Synonyms
FLA 22
BRN 1298536
607-75-0
(gamma-Dimethylaminopropyl)-amid der flavon-7-oxyessigsaeure [German]
N-(3-(Dimethylamino)propyl)-2-((4-oxo-2-phenyl-4H-1-benzopyran-7-yl)oxy)acetamide
DTXSID20209518
Flavon-7-oxyessigsaeure-(gamma-dimethylaminopropyl)amid [German]
Acetamide, N-(3-(dimethylamino)propyl)-2-((4-oxo-2-phenyl-4H-1-benzopyran-7-yl)oxy)-
Flavon-7-oxyessigsaeure-(gamma-dimethylaminopropyl)amid
(gamma-Dimethylaminopropyl)-amid der flavon-7-oxyessigsaeure
DTXCID70132009
5-18-02-00264 (beilstein handbook reference)