Skip to main content

Lidocaine

ADVERTISEMENT
Identification
Molecular formula
C14H22N2O
CAS number
137-58-6
IUPAC name
N-[3-(dimethylamino)propyl]-N-(2,6-dimethylphenyl)-2-ethyl-butanamide
State
State

At room temperature, lidocaine is typically in a solid state, appearing as a powder. When in its hydrochloride form, it remains solid and is often used in aqueous solutions for medical applications.

Melting point (Celsius)
66.00
Melting point (Kelvin)
339.15
Boiling point (Celsius)
350.00
Boiling point (Kelvin)
623.15
General information
Molecular weight
234.34g/mol
Molar mass
234.3370g/mol
Density
1.0260g/cm3
Appearence

Lidocaine appears as a white, crystalline powder. It is odorless and has a slightly bitter taste. The compound is often used in its hydrochloride form, which is also white and crystalline.

Comment on solubility

Solubility of N-[3-(dimethylamino)propyl]-N-(2,6-dimethylphenyl)-2-ethyl-butanamide

The solubility of N-[3-(dimethylamino)propyl]-N-(2,6-dimethylphenyl)-2-ethyl-butanamide can depend on several factors due to its complex structure. Here are some key points to consider:

  • Polarity: The presence of the dimethylamino group suggests some polar characteristics, while the bulky phenyl ring may introduce hydrophobic features. This combination can affect interactions with solvents.
  • Solvent Type: This compound may be better soluble in organic solvents such as ethanol or dichloromethane compared to water, which is a common trend for amides that contain large hydrophobic groups.
  • Temperature Dependency: As with many organic compounds, solubility can increase with temperature; thus, elevating the temperature might enhance the solubility in selected solvents.
  • Aqueous Solubility: It may exhibit limited aqueous solubility due to its non-polar characteristics, which are exacerbated by the large hydrocarbon tails.

In conclusion, the solubility of N-[3-(dimethylamino)propyl]-N-(2,6-dimethylphenyl)-2-ethyl-butanamide is likely influenced by both its structural features and the nature of the solvent, adding a layer of complexity that invites further investigation.

Interesting facts

Interesting Facts about N-[3-(dimethylamino)propyl]-N-(2,6-dimethylphenyl)-2-ethyl-butanamide

N-[3-(dimethylamino)propyl]-N-(2,6-dimethylphenyl)-2-ethyl-butanamide is a fascinating compound with unique properties and applications. Here are some intriguing details that highlight its significance in the realm of chemistry:

  • Pharmaceutical Applications: This compound has been studied for its potential uses in medicinal chemistry, particularly in the design of new pharmaceuticals. Its structure allows for interactions with biological targets, making it an interesting candidate for drug discovery.
  • Analogue Development: Due to its complex amide linkage and the presence of dimethylamino groups, modifications to similar compounds can lead to a range of analogues. This is crucial in pharmacology, where small changes can significantly alter biological activity.
  • Synthesis Techniques: The synthesis of N-[3-(dimethylamino)propyl]-N-(2,6-dimethylphenyl)-2-ethyl-butanamide involves multiple steps and reagents, showcasing advanced techniques in organic synthesis. These strategies can be applied to create diverse compounds in laboratory settings.
  • Research Significance: There is ongoing research into the biological activity of this compound. Scientists are keen to uncover its mechanism of action, particularly how it interacts with cellular pathways.
  • Aspect of Selectivity: The compounds built around a bulky dimethylphenyl group can display selectivity in receptor binding, which is vital for developing targeted therapies with fewer side effects.

In summary, N-[3-(dimethylamino)propyl]-N-(2,6-dimethylphenyl)-2-ethyl-butanamide serves as a prime example of how intricate molecular design can lead to impactful applications in the field of chemistry and medicine. As we continue exploring its properties, we open doors to innovative solutions in drug development and therapeutic strategies.

Synonyms
SA 62
20682-39-7
BRN 2751319
BUTYRANILIDE, N-(3-(DIMETHYLAMINO)PROPYL)-2',6'-DIMETHYL-2-ETHYL-
DTXSID20174737
N-(3-(Dimethylamino)propyl)-2',6'-dimethyl-2-ethylbutyranilide
DTXCID7097228
RefChem:331219
N-[3-(dimethylamino)propyl]-N-(2,6-dimethylphenyl)-2-ethylbutanamide
SCHEMBL29393009
DB-308920
N-[3-(dimethylamino)propyl ]-N-(2,6-dimethylphenyl )-2-ethylbutyramide