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Lidocaine

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Identification
Molecular formula
C14H22N2O
CAS number
137-58-6
IUPAC name
N-[3-(dimethylamino)propyl]-N-(2,6-dimethylphenyl)-2-phenyl-butanamide
State
State

At room temperature, lidocaine is typically in a solid state as a crystalline powder.

Melting point (Celsius)
66.00
Melting point (Kelvin)
339.20
Boiling point (Celsius)
350.80
Boiling point (Kelvin)
623.80
General information
Molecular weight
234.34g/mol
Molar mass
234.3370g/mol
Density
1.0260g/cm3
Appearence

Lidocaine typically appears as a white to off-white powder. It is crystalline and has a characteristic mild amine odor. It is often encountered in its hydrochloride form, which is more soluble in water.

Comment on solubility

Solubility of N-[3-(dimethylamino)propyl]-N-(2,6-dimethylphenyl)-2-phenyl-butanamide

The solubility of the compound N-[3-(dimethylamino)propyl]-N-(2,6-dimethylphenyl)-2-phenyl-butanamide can be quite variable depending on several factors such as temperature, solvent type, and pH. Here are some key points to consider:

  • Solvent Compatibility: This compound is likely to exhibit moderate to high solubility in organic solvents such as dichloromethane and ethanol due to its non-polar and amphiphilic characteristics.
  • Polar vs Non-Polar Solvents: The presence of the dimethylamino group provides some level of polarity, which can enhance solubility in polar solvents, although it primarily remains hydrophobic.
  • Temperature Influence: As with many organic compounds, increasing the temperature may improve solubility, allowing for greater interaction with solvents.
  • pH Sensitivity: In an aqueous environment, the solubility can also be affected by the pH, particularly if protonation of the amino group occurs, leading to increased solubility in acidic conditions.

In summary, while N-[3-(dimethylamino)propyl]-N-(2,6-dimethylphenyl)-2-phenyl-butanamide might not be soluble in water, its solubility in organic solvents can be significant, making it suitable for various chemical applications.

Interesting facts

Interesting Facts about N-[3-(dimethylamino)propyl]-N-(2,6-dimethylphenyl)-2-phenyl-butanamide

N-[3-(dimethylamino)propyl]-N-(2,6-dimethylphenyl)-2-phenyl-butanamide, often referred to in the research community for its complex structure and potential applications, is a notable compound with several intriguing characteristics:

  • Versatile Uses: This compound is recognized for its potential in medicinal chemistry, often being explored for its properties related to neurotransmitter modulation, making it a compound of interest in the field of neuropharmacology.
  • Structure-Activity Relationships: The intricate molecular structure of this compound allows scientists to examine how modifications to its various functional groups can lead to different biological activities. This understanding is crucial in drug design.
  • Dimethylamino Group: The presence of the dimethylamino functional group enhances the compound's basicity, which can impact its interaction with biological targets, making it a subject of study for chemists and pharmacologists alike.
  • Research Significance: Investigations of this compound can shed light on the mechanisms of action related to certain receptors in the brain, contributing to our understanding of conditions such as anxiety and depression. Scientists often say, "Understanding the structure opens doors to therapeutic innovations."

The exploration of compounds like N-[3-(dimethylamino)propyl]-N-(2,6-dimethylphenyl)-2-phenyl-butanamide not only reveals the beauty of organic chemistry but also underscores the potential of synthetic compounds in developing new treatments and understanding complex biological processes. It's truly an exciting area of study!

Synonyms
17307-22-1
SA 164
N-(3-(Dimethylamino)propyl)-2',6'-dimethyl-2-phenylbutyranilide
BUTYRANILIDE, N-(3-(DIMETHYLAMINO)PROPYL)-2',6'-DIMETHYL-2-PHENYL-
N-[3-(dimethylamino)propyl]-N-(2,6-dimethylphenyl)-2-phenylbutanamide
N-[3-(Dimethylamino)propyl]-N-(2,6-dimethylphenyl)-2-phenylbutyramide
SCHEMBL29739742
DTXSID80938291