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Lidocaine

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Identification
Molecular formula
C14H22N2O
CAS number
137-58-6
IUPAC name
N-[3-(dimethylamino)propyl]-N-(2,6-dimethylphenyl)-2,2-diphenyl-acetamide
State
State
Lidocaine is generally a solid at room temperature and is available in various forms including powders and liquid solutions for medical use.
Melting point (Celsius)
68.00
Melting point (Kelvin)
341.15
Boiling point (Celsius)
180.00
Boiling point (Kelvin)
453.15
General information
Molecular weight
234.34g/mol
Molar mass
234.3390g/mol
Density
1.0260g/cm3
Appearence

Lidocaine is typically encountered as a white, crystalline powder. It is odorless and has a slightly bitter taste.

Comment on solubility

Solubility of N-[3-(dimethylamino)propyl]-N-(2,6-dimethylphenyl)-2,2-diphenyl-acetamide

The solubility of N-[3-(dimethylamino)propyl]-N-(2,6-dimethylphenyl)-2,2-diphenyl-acetamide can be quite complex due to its structural characteristics. Several factors influence its solubility:

  • Polarity: The presence of dimethylamino and phenyl groups suggests some polar and non-polar characteristics, which can affect solubility in various solvents.
  • Hydrophobic interactions: The diphenyl structure may contribute to hydrophobic character, potentially limiting solubility in water but enhancing solubility in organic solvents.
  • Temperature: Solubility can vary significantly with temperature; increased temperature typically increases solubility for most compounds.

In general, we can summarize the solubility characteristics as follows:

  1. May show low solubility in water due to its hydrophobic parts.
  2. More likely to dissolve well in organic solvents such as alcohols, ethers, or chloroform.
  3. Careful consideration of the pH can also play a role, as it can affect the ionization state of the dimethylamino group.

Overall, the solubility of N-[3-(dimethylamino)propyl]-N-(2,6-dimethylphenyl)-2,2-diphenyl-acetamide is influenced by a combination of molecular structure, solvent choice, and environmental conditions. Each of these factors should be considered when assessing its behavior in different media.

Interesting facts

Interesting Facts about N-[3-(dimethylamino)propyl]-N-(2,6-dimethylphenyl)-2,2-diphenyl-acetamide

N-[3-(dimethylamino)propyl]-N-(2,6-dimethylphenyl)-2,2-diphenyl-acetamide is a fascinating compound in the field of medicinal chemistry, primarily recognized for its pharmacological properties. This compound belongs to the class of amides and exhibits a unique structural composition, making it a subject of interest for various therapeutic applications.

Key Features:

  • Biological Activity: The compound is known for its potential activity as an analgesic and anti-inflammatory agent, opening up avenues for research in pain management.
  • Structural Complexity: The intricate arrangement of multiple functional groups provides insights into structure-activity relationships, which are crucial in drug design.
  • Dimethylamino Group: The presence of the dimethylamino group enhances the compound's lipophilicity, which can influence its bioavailability and pharmacokinetics.
  • Role in Medicinal Chemistry: Such compounds often serve as prototypes for the development of new pharmaceuticals, where minor modifications can lead to significant changes in activity.

As noted by researchers in this domain, "Understanding the interplay of different substituents can pave the way for novel drug discovery." This highlights the importance of studying derivatives like N-[3-(dimethylamino)propyl]-N-(2,6-dimethylphenyl)-2,2-diphenyl-acetamide in the quest for innovative therapeutic agents.

In conclusion, the exploration of this compound not only enriches our knowledge of chemical interactions but also underscores the profound impact that even small molecular modifications can have on biological activity, making it a cornerstone in the pursuit of effective medicines.

Synonyms
SA 65
17307-20-9
BRN 2781757
ACETANILIDE, N-(3-(DIMETHYLAMINO)PROPYL)-2',6'-DIMETHYL-2,2-DIPHENYL-
DTXSID80169508
N-(3-(Dimethylamino)propyl)-2',6'-dimethyl-2,2-diphenylacetanilide
DTXCID9091999
SCHEMBL29393900