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Lidocaine

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Identification
Molecular formula
C14H22N2O
CAS number
137-58-6
IUPAC name
N-[3-(dimethylamino)propyl]-N-(2,6-dimethylphenyl)-3-phenyl-prop-2-enamide
State
State

At room temperature, Lidocaine is in a solid state, typically found as a crystalline powder.

Melting point (Celsius)
66.00
Melting point (Kelvin)
339.15
Boiling point (Celsius)
180.00
Boiling point (Kelvin)
453.15
General information
Molecular weight
234.33g/mol
Molar mass
234.3330g/mol
Density
1.0300g/cm3
Appearence

Lidocaine typically appears as a white or almost white crystalline solid. It is odorless or has a faint characteristic odor.

Comment on solubility

Solubility of N-[3-(dimethylamino)propyl]-N-(2,6-dimethylphenyl)-3-phenyl-prop-2-enamide

The solubility of N-[3-(dimethylamino)propyl]-N-(2,6-dimethylphenyl)-3-phenyl-prop-2-enamide is a significant aspect to consider for its applications in various fields. This compound features a complex molecular structure with both hydrophobic and hydrophilic characteristics, influencing its ability to dissolve in different solvents.

Factors Influencing Solubility:

  • Polarity: The presence of the dimethylamino group tends to increase polarity, potentially enhancing solubility in polar solvents.
  • Hydrophobic Interactions: The 2,6-dimethylphenyl and phenyl groups contribute to hydrophobic interactions, which might limit its solubility in water.
  • Solvent Choice: This compound is generally more soluble in organic solvents such as ethanol, methanol, or acetone rather than in water.

As a result, one might observe:

  • Higher solubility in polar organic solvents.
  • Lower solubility in non-polar solvents due to the intricate molecular design.
  • Temperature Dependency: Solubility can vary with temperature changes, often increasing at higher temperatures.

In conclusion, understanding the solubility of this compound requires a careful exploration of its molecular features and solvent interactions. The balancing act between its polar and non-polar components is crucial for predicting its behavior in various chemical environments.

Interesting facts

Interesting Facts about N-[3-(dimethylamino)propyl]-N-(2,6-dimethylphenyl)-3-phenyl-prop-2-enamide

N-[3-(dimethylamino)propyl]-N-(2,6-dimethylphenyl)-3-phenyl-prop-2-enamide, often referred to in scientific contexts as a novel chemical entity, boasts a fascinating combination of structural features that contribute to its unique properties and applications. Here are some interesting points about this compound:

  • Multi-Functional Group: The presence of both amide and enamide functional groups in its structure allows for diverse reactivity, making it a valuable candidate in medicinal chemistry.
  • Dimethylamino Moiety: The dimethylamino group is notable for enhancing the solubility and stability of the compound, which may benefit its bioavailability in pharmaceutical formulations.
  • Biological Activity: Compounds with similar architectures have been studied for their potential activity against various biological targets, including those important in neuroscience and oncology.
  • Chirality: Depending on the synthesis route, the compound can exist in different stereoisomeric forms, which can exhibit significantly different biological properties, highlighting the importance of chirality in drug design.

As scientists continue to explore this compound, its potential applications in drug development and biochemical research could pave the way for innovative treatments and expand our understanding of complex biological systems. The intricate balance of its structural elements makes it a subject of great interest in contemporary chemistry!