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Phenacetin

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Identification
Molecular formula
C10H13NO2
CAS number
62-44-2
IUPAC name
N-(3-ethoxyphenyl)acetamide
State
State

At room temperature, Phenacetin is typically in a solid state. It is not hygroscopic, meaning it does not absorb moisture from the air, and retains a stable configuration under standard conditions. It is insoluble in water but soluble in organic solvents such as alcohol, acetone, and ether.

Melting point (Celsius)
134.00
Melting point (Kelvin)
407.15
Boiling point (Celsius)
132.00
Boiling point (Kelvin)
405.15
General information
Molecular weight
179.22g/mol
Molar mass
179.2160g/mol
Density
1.1290g/cm3
Appearence

Phenacetin appears as a white, crystalline solid or powder. It is known for its glossy, silk-like and fibrous texture. The substance can occur in flattened, needle-like crystals, making it visually distinctive under microscopic observation.

Comment on solubility

Solubility of N-(3-ethoxyphenyl)acetamide

N-(3-ethoxyphenyl)acetamide is an organic compound that showcases interesting solubility characteristics influenced by its functional groups and molecular structure. This compound is primarily soluble in organic solvents, such as:

  • Ethyl acetate
  • Dichloromethane
  • Acetone

However, it exhibits limited solubility in polar solvents like water. This can be attributed to the presence of the ethoxy group, which enhances the hydrophobic character of the molecule, thereby making it less compatible with polar environments. In general, compounds that contain:

  • Hydrophobic aromatic rings
  • Aliphatic chains

tend to show decreased solubility in water. The degree of solubility can further be affected by temperature and pH, with higher temperatures often improving solubility in organic solvents. Additionally, solubility may vary based on the presence of other solutes or interactions in a mixed solvent system.

Overall, while N-(3-ethoxyphenyl)acetamide demonstrates favorable solubility in non-polar solvents, its behavior in aqueous solutions reflects a common trend seen with many organic compounds, where solubility is dictated by the balance between hydrophilic and hydrophobic interactions.

Interesting facts

Interesting Facts about N-(3-ethoxyphenyl)acetamide

N-(3-ethoxyphenyl)acetamide is a fascinating compound that belongs to the class of amides. Here are some intriguing aspects of this chemical:

  • Structural Diversity: As an amide, N-(3-ethoxyphenyl)acetamide features an ethoxy group attached to a phenyl ring, showcasing the compound's rich structural diversity. This structural configuration not only influences its chemical behavior but also its potential applications in various fields.
  • Potential Pharmacological Applications: Compounds similar to N-(3-ethoxyphenyl)acetamide have been studied for their biological activities. There is potential for developing therapeutic agents given their interactions with biological systems.
  • Synthetic Pathways: The synthesis of N-(3-ethoxyphenyl)acetamide can provide insight into important reaction mechanisms in organic chemistry. Understanding these pathways can help chemists design more efficient synthetic routes for similar compounds.
  • Research Opportunities: The unique properties of this compound invite research into its reactivity and interaction with other biological molecules, potentially leading to innovations in medicinal chemistry.

In essence, N-(3-ethoxyphenyl)acetamide exemplifies the complexity and utility of organic chemistry, serving as a reminder of the interplay between structure and function in chemical compounds. Exploring compounds like this one opens doors to new discoveries in science.

Synonyms
3'-Ethoxyacetanilide
N-(3-Ethoxyphenyl)acetamide
Acetanilide, 3'-ethoxy-
Acetamide, N-(3-ethoxyphenyl)-
NSC 7650
EINECS 209-713-3
0X00AE1BZW
BRN 2691816
NSC-7650
UNII-0X00AE1BZW
3-13-00-00950 (Beilstein Handbook Reference)
DTXSID8060450
DTXCID9042542
209-713-3
591-33-3
m-Acetophenetidide
m-Ethoxyacetanilide
3-ETHOXYACETANILIDE
3-Acetophenetidide
N-acetyl-m-phenetidine
4-ethoxy-2-acetaminobenzene
WLN: 2OR CMV1
SCHEMBL10264545
NSC7650
YVTBOWVWYXJHLD-UHFFFAOYSA-N
AAA59133
AKOS001603877
AS-75905
CS-0438595
EU-0069602
NS00034094
3 inverted exclamation marka-Ethoxyacetanilide
SR-01000414402
SR-01000414402-1