Interesting facts
Interesting Facts about N-(3-Fluorophenyl)acetamide
N-(3-Fluorophenyl)acetamide is a fascinating compound that belongs to the class of acetamides, which are derived from acetic acid and often utilized in a variety of applications in organic chemistry. Here are several notable aspects of this compound:
- Fluorine Substitution: The presence of a fluorine atom in the aromatic ring significantly affects the chemical properties of the compound. Fluorine is known for its electronegative nature, which can influence reactivity and interaction with other molecules.
- Biological Activity: Compounds similar to N-(3-Fluorophenyl)acetamide may exhibit interesting biological properties. Fluorinated amides are often investigated in medicinal chemistry due to their potential therapeutic applications.
- Synthetic Utility: N-(3-Fluorophenyl)acetamide can serve as an important intermediate in the synthesis of various pharmaceuticals and agrochemicals, demonstrating its utility in drug design and development.
- Research Interest: Scientists are continuously researching fluorinated compounds like this one for their role in enhancing the pharmacokinetic properties of drugs, particularly in improving bioavailability and metabolic stability.
In summary, N-(3-Fluorophenyl)acetamide is more than just a simple acetamide; it is a compound that exemplifies the intriguing interplay of structure and function in organic chemistry. As noted by chemists, "The uniqueness of fluorinated compounds lies in their ability to tweak biological interactions, making them invaluable in drug discovery." This attribute continues to position N-(3-Fluorophenyl)acetamide as a subject of ongoing scientific exploration.
Synonyms
3'-Fluoroacetanilide
351-28-0
N-(3-FLUOROPHENYL)ACETAMIDE
3-Fluoroacetanilide
m-Fluoroacetanilide
MFCD00017917
Acetamide, N-(3-fluorophenyl)-
NF7XTQ6SQD
EINECS 206-509-6
Acetanilide, 3'-fluoro-
DTXSID00188594
3-Acetamido-1-fluorobenzene
NSC 10348
NSC-10348
1-fluoro-3-acetamidobenzene
NSC10348
UNII-NF7XTQ6SQD
3'-Fluoroacetanilide, 98%
SCHEMBL687148
N-(3-Fluorophenyl)acetamide #
N-methylcarbonyl 3-fluoroaniline
DTXCID60111085
AKOS002960249
AB11466
CS-W017741
PS-8901
SB76040
SY040632
DB-048733
F0302
NS00041423
3 inverted exclamation mark -Fluoroacetanilide
EN300-98408
Z28143124
206-509-6
Solubility of N-(3-fluorophenyl)acetamide
N-(3-fluorophenyl)acetamide, characterized by its unique structure, exhibits intriguing solubility properties that are significant for its application in various fields. The solubility of organic compounds like N-(3-fluorophenyl)acetamide is influenced by several factors:
Experimental data suggests that "like dissolves like", meaning polar compounds are more soluble in polar solvents and vice versa. Therefore, while N-(3-fluorophenyl)acetamide shows reasonably good solubility in a range of solvents, its solubility is notably enhanced in polar environments. Understanding these solubility aspects is crucial for its handling and application in chemical processes.