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Acetaminophen

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Identification
Molecular formula
C20H21NO3
CAS number
103-90-2
IUPAC name
N-[3-hydroxy-1-(4-methoxyphenyl)-3,3-diphenyl-propyl]acetamide
State
State

At room temperature, acetaminophen is in a solid state. It is typically found in pharmacy products in pill, tablet, or capsule form, utilized for its analgesic and antipyretic properties.

Melting point (Celsius)
169.00
Melting point (Kelvin)
442.15
Boiling point (Celsius)
420.00
Boiling point (Kelvin)
693.15
General information
Molecular weight
268.33g/mol
Molar mass
268.3320g/mol
Density
1.2637g/cm3
Appearence

Acetaminophen, commonly known as Paracetamol, appears as a white, crystalline powder. It is odorless and slightly bitter to taste. This compound is generally supplied in its powdered form, suitable for compounding into tablet and capsule formulations.

Comment on solubility

Solubility of N-[3-hydroxy-1-(4-methoxyphenyl)-3,3-diphenyl-propyl]acetamide

N-[3-hydroxy-1-(4-methoxyphenyl)-3,3-diphenyl-propyl]acetamide is a compound whose solubility can be influenced by several factors. Its complex structure includes multiple aromatic rings and functional groups, which are known to affect how the compound interacts with solvents:

  • Polar solvents: Due to the presence of hydroxyl (-OH) and acetamide groups, this compound may show some degree of solubility in polar solvents like water and methanol. The ability of these functional groups to form hydrogen bonds can enhance solubility.
  • Non-polar solvents: The compound is likely to also dissolve in non-polar solvents, including ethanol or chloroform, due to the large hydrophobic diphenyl and methoxyphenyl sections of the molecule.
  • Temperature dependence: The solubility of this compound may increase with temperature. As temperature rises, solvent molecules gain kinetic energy, often leading to improved solubility of organic compounds.

It is crucial to note that the solubility can vary based on conditions and concentrations. To determine solubility more precisely, experimental data is recommended. As always, the structural characteristics of a compound can provide a strong indication of its behavior in various solvents, making this compound a fascinating subject of study regarding solubility.

Interesting facts

Interesting Facts about N-[3-hydroxy-1-(4-methoxyphenyl)-3,3-diphenyl-propyl]acetamide

N-[3-hydroxy-1-(4-methoxyphenyl)-3,3-diphenyl-propyl]acetamide, commonly referred to as a specific derivative within the class of acetamide compounds, showcases remarkable properties that intrigue chemists and pharmacologists alike. This compound is particularly noted for its potential medicinal applications and the complexity of its molecular structure.

Unique Characteristics

  • Pharmacological Potential: Compounds like this one have been studied for their effects on various biological pathways. They may exhibit anti-inflammatory or analgesic properties, making them of interest in therapeutic research.
  • Phenyl Groups: The presence of multiple phenyl groups in its structure contributes to its stability and hydrophobic characteristics, which can influence its pharmacokinetics and interaction with biological targets.
  • Onto Synthesis: The synthetic route for this compound often involves sophisticated organic reactions, illustrating the intricate techniques needed to assemble such a complex molecule.

Key Research Areas

Scientists are conducting ongoing research into:

  • Mechanism of Action: Understanding how N-[3-hydroxy-1-(4-methoxyphenyl)-3,3-diphenyl-propyl]acetamide interacts with cellular targets can unveil its therapeutic potential.
  • Structure-Activity Relationship (SAR): Altering various parts of the molecule can lead to significant changes in its medicinal properties, providing a rich area for exploration.
  • Safety and Efficacy: Preclinical studies to assess toxicity and effectiveness are vital to determine its suitability for human use.

In conclusion, N-[3-hydroxy-1-(4-methoxyphenyl)-3,3-diphenyl-propyl]acetamide stands out due to its complex structure and significant implications in pharmaceutical chemistry. As research progresses, it may pave the way for novel treatments and a deeper understanding of drug design.

Synonyms
3-Acetamido-3-(p-anisyl)-1,1-diphenyl-1-propanol
14593-00-1
ACETAMIDE, N-(3,3-DIPHENYL-3-HYDROXY-1-(P-METHOXYPHENYL)PROPYL)-
DTXSID90932720
N-[3-Hydroxy-1-(4-methoxyphenyl)-3,3-diphenylpropyl]ethanimidic acid