Aclarubicin | Solubility of Things

Identification

Molecular formula

C₂₅H₂₇N₃O₉

CAS number

57576-44-0

IUPAC name

N-(3-hydroxy-1,2,10-trimethoxy-9-oxo-6,7,10,11-tetrahydro-5H-benzo[a]heptalen-7-yl)acetamide

State

At room temperature, aclarubicin is typically a solid.

Melting point (Celsius)

233.00

Melting point (Kelvin)

506.15

Boiling point (Celsius)

700.00

Boiling point (Kelvin)

973.15

General information

Molecular weight

625.67g/mol

Molar mass

625.6730g/mol

Density

1.2635g/cm³

Appearence

A deep red or dark brown crystalline powder.

Comment on solubility

Solubility Insights

The solubility of N-(3-hydroxy-1,2,10-trimethoxy-9-oxo-6,7,10,11-tetrahydro-5H-benzo[a]heptalen-7-yl)acetamide can present an intriguing case for researchers and chemists alike. This compound's complex structure, characterized by multiple functional groups, influences its interaction with solvents.

Factors Influencing Solubility

Several factors impact the solubility of this compound:

Polar and Nonpolar Regions: The presence of hydroxyl and methoxy groups suggests it may have some degree of polarity, potentially enhancing solubility in polar solvents like water.
Hydrophobic Core: The benzenoid structure may create a hydrophobic region, complicating solubility in aqueous solutions.
Temperature: As with many organic compounds, solubility can increase with temperature, allowing for broader insights when conducting experiments at varied conditions.

Overall, it is likely that while N-(3-hydroxy-1,2,10-trimethoxy-9-oxo-6,7,10,11-tetrahydro-5H-benzo[a]heptalen-7-yl)acetamide may exhibit moderate solubility in certain polar organic solvents, accessibility in aqueous phases might be limited without appropriate modifications or solubilizing agents. Understanding these characteristics is crucial for its practical applications and effective usage in chemical processes.

Interesting facts

Interesting Facts about N-(3-hydroxy-1,2,10-trimethoxy-9-oxo-6,7,10,11-tetrahydro-5H-benzo[a]heptalen-7-yl)acetamide

N-(3-hydroxy-1,2,10-trimethoxy-9-oxo-6,7,10,11-tetrahydro-5H-benzo[a]heptalen-7-yl)acetamide is a fascinating compound that draws significant interest in the fields of medicinal chemistry and pharmacology. This compound belongs to the class of benzo[a]heptalenes, which are known for their complex structures and intriguing biological activities. Here are some captivating aspects of this compound:

Biological Potential: Compounds derived from benzo[a]heptalenes have been studied for their potential therapeutic effects, including anti-cancer and anti-inflammatory properties, making them subjects of interest in drug discovery.
Structure Complexity: The presence of multiple methoxy groups and a ketone functionality within the molecule creates an intricate 3D structure, which can significantly influence its reactivity and interaction with biological targets.
Hydroxyl Group Role: The hydroxyl group at position 3 is thought to enhance hydrogen bonding, potentially contributing to the compound's solubility and ability to form interactions with receptor sites.
Research Applications: Due to its unique structure, this compound can serve as a valuable lead compound for further modifications aimed at enhancing its efficacy and selectivity in biological systems.

This compound exemplifies the importance of structural diversity in organic chemistry, highlighting how subtle changes in molecular architecture can lead to significant variations in biological activity. As a result, ongoing research into N-(3-hydroxy-1,2,10-trimethoxy-9-oxo-6,7,10,11-tetrahydro-5H-benzo[a]heptalen-7-yl)acetamide may pave the way for new therapeutic agents and inspire a deeper understanding of complex molecular interactions.