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Identification
Molecular formula
C22H25NO2
CAS number
124937-52-6
IUPAC name
N-(3-hydroxy-1,3,3-triphenyl-propyl)acetamide
State
State

At room temperature, N-(3-hydroxy-1,3,3-triphenyl-propyl)acetamide is typically in a solid state as a crystalline powder.

Melting point (Celsius)
131.00
Melting point (Kelvin)
404.15
Boiling point (Celsius)
397.00
Boiling point (Kelvin)
670.15
General information
Molecular weight
349.45g/mol
Molar mass
349.4480g/mol
Density
1.1699g/cm3
Appearence

N-(3-hydroxy-1,3,3-triphenyl-propyl)acetamide appears as a white to off-white crystalline powder.

Comment on solubility

Solubility of N-(3-hydroxy-1,3,3-triphenyl-propyl)acetamide

N-(3-hydroxy-1,3,3-triphenyl-propyl)acetamide, often recognized for its unique structure, exhibits specific solubility characteristics that are crucial for its application in various fields.

Generally, the solubility of this compound in various solvents can be summarized as follows:

  • Water: This compound tends to have limited solubility in water due to its bulky hydrophobic triphenyl groups, which hinder interaction with polar water molecules.
  • Organic Solvents: It is likely to be more soluble in non-polar to moderately polar organic solvents such as ethanol, methanol, and acetone. The presence of the acetamide group provides some degree of polar character, enhancing solubility in certain organics.
  • pH Dependence: The solubility may also be influenced by the pH of the solvent, particularly due to the hydroxyl and amide functionalities that can engage in hydrogen bonding.

As noted, the combination of hydrophobic and hydrophilic characteristics leads to a complex solubility profile. In essence, one could say:

"The solubility of N-(3-hydroxy-1,3,3-triphenyl-propyl)acetamide is an interplay of its molecular structure and the solvent environment."

This understanding is vital for optimizing its use in chemical processes and formulations, where solubility can play a central role in effectiveness and transport.

Interesting facts

Interesting Facts about N-(3-hydroxy-1,3,3-triphenyl-propyl)acetamide

N-(3-hydroxy-1,3,3-triphenyl-propyl)acetamide, commonly referred to as a potential therapeutic compound, exhibits intriguing properties that pique the interest of chemists and pharmacologists alike. Here are some notable facts:

  • Pharmacological Relevance: This compound has shown potential in pharmacological studies, particularly due to its structural similarity to known therapeutic agents, indicating possible applications in treating various medical conditions.
  • Hydroxyl Group Significance: The presence of the hydroxy group in its structure enhances its polarity, potentially influencing its interaction with biological targets and increasing its solubility in biological systems.
  • Triphenyl Moiety: The triphenyl segment contributes significantly to the compound's stability and could affect its biological activity through mechanisms such as electron donation or steric hindrance.
  • Derivatives and Analogues: The synthesis of derivatives and analogues of this compound offers a pathway for exploring a range of biological activities, leading to innovative drug design and therapeutic approaches.
  • Research Interests: Scientists are encouraged to explore this compound due to its unique structure, which presents opportunities for investigations into structure-activity relationships (SAR) and the development of more effective compounds in medicinal chemistry.

While N-(3-hydroxy-1,3,3-triphenyl-propyl)acetamide may not yet be widely recognized, its complex structure and potential applications in medicine make it a fascinating subject for ongoing research and study in the field of pharmacology.

Synonyms
14593-09-0
N-(3-Hydroxy-1,3,3-triphenylpropyl)acetamide
BRN 3437177
1,1,3-Triphenyl-3-acetamido-1-propanol
3-Acetamido-1,1,3-triphenyl-1-propanol
ACETAMIDE, N-(3-HYDROXY-1,3,3-TRIPHENYLPROPYL)-
4-13-00-02292 (Beilstein Handbook Reference)
DTXSID90932725
N-(3-Hydroxy-1,3,3-triphenylpropyl)ethanimidic acid