N-[3-hydroxy-4-(piperidine-1-carbonyl)phenyl]-2-(1-piperidyl)acetamide

Identification

Molecular formula

C₁₉H₂₈N₄O₃

CAS number

IUPAC name

N-[3-hydroxy-4-(piperidine-1-carbonyl)phenyl]-2-(1-piperidyl)acetamide

State

At room temperature, N-[3-hydroxy-4-(piperidine-1-carbonyl)phenyl]-2-(1-piperidyl)acetamide exists as a solid. It is relatively stable when stored in dry conditions and away from strong direct light.

Melting point (Celsius)

216.00

Melting point (Kelvin)

489.15

Boiling point (Celsius)

517.80

Boiling point (Kelvin)

790.95

General information

Molecular weight

330.43g/mol

Molar mass

330.4290g/mol

Density

1.2193g/cm³

Appearence

N-[3-hydroxy-4-(piperidine-1-carbonyl)phenyl]-2-(1-piperidyl)acetamide is typically found as a crystalline solid. It can be white or off-white in color, depending on its purity and any incorporated impurities.

Comment on solubility

Solubility of N-[3-hydroxy-4-(piperidine-1-carbonyl)phenyl]-2-(1-piperidyl)acetamide

The solubility of N-[3-hydroxy-4-(piperidine-1-carbonyl)phenyl]-2-(1-piperidyl)acetamide can significantly influence its behavior in various environments, such as biological systems or chemical processes. Understanding its solubility properties is essential for effectively utilizing this compound. Here are some key considerations:

Polarity: The compound features multiple functional groups, including a hydroxyl group and amide linkages, which suggest that it may exhibit moderate to high polarity.
Solvent Compatibility: It is likely to be more soluble in polar solvents, such as water or alcohols, due to the presence of the hydroxyl group that can engage in hydrogen bonding.
Temperature Dependence: The solubility may increase with temperature, as is common with many organic compounds, particularly when they incorporate polar functionalities.
pH Influence: The solubility could also be affected by the pH of the solution, as ionization of the amide group can enhance solubility in basic conditions.

In conclusion, while the exact solubility profile may vary based on specific conditions, it is reasonable to hypothesize that N-[3-hydroxy-4-(piperidine-1-carbonyl)phenyl]-2-(1-piperidyl)acetamide presents a favorable solubility in polar solvents, particularly under higher temperatures or varying pH levels. Understanding these factors is crucial for applications in pharmaceutical formulations and chemical research.

Interesting facts

Interesting Facts about N-[3-hydroxy-4-(piperidine-1-carbonyl)phenyl]-2-(1-piperidyl)acetamide

This chemical compound, often referred to in the field of medicinal chemistry, has garnered attention due to its potential therapeutic applications. Here are some fascinating aspects of this compound:

Pharmacological Relevance: N-[3-hydroxy-4-(piperidine-1-carbonyl)phenyl]-2-(1-piperidyl)acetamide is being studied for its properties that might influence neurological pathways, potentially making it useful in the treatment of various psychiatric disorders.
Chemical Structure: The presence of a piperidine ring is noteworthy as it is a common motif in many bioactive compounds. This ring enhances the compound's ability to traverse biological membranes, which is crucial for its therapeutic efficacy.
Hydroxyl Group Influence: The hydroxyl group on the aromatic ring contributes to the compound's hydrogen bonding potential, potentially influencing its binding to target receptors in biological systems.
Structure-Activity Relationship (SAR): Understanding the SAR is vital in medicinal chemistry, and this compound exemplifies how subtle changes in molecular structure can lead to significant changes in biological activity.
Research Directions: Current studies may include exploring its mechanism of action, interaction with specific protein targets, and evaluating its pharmacokinetic properties, which could illuminate pathways toward clinical applications.

As researchers continue to delve into the complexities of this compound, it stands as a testament to the intricate dance between chemistry and pharmacology.

In conclusion, N-[3-hydroxy-4-(piperidine-1-carbonyl)phenyl]-2-(1-piperidyl)acetamide not only showcases the intricate relationships in chemical structures but also highlights the significant gaps in our knowledge that still exist in drug discovery and development.