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N-(3-hydroxy-9H-fluoren-2-yl)acetamide

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Identification
Molecular formula
C15H13NO2
CAS number
5875-83-4
IUPAC name
N-(3-hydroxy-9H-fluoren-2-yl)acetamide
State
State
The compound is a solid at room temperature.
Melting point (Celsius)
209.00
Melting point (Kelvin)
482.15
Boiling point (Celsius)
425.30
Boiling point (Kelvin)
698.45
General information
Molecular weight
239.27g/mol
Molar mass
239.2630g/mol
Density
1.3220g/cm3
Appearence

The compound is typically seen as a crystalline solid. Its color ranges from off-white to pale yellow.

Comment on solubility

Solubility of N-(3-hydroxy-9H-fluoren-2-yl)acetamide

N-(3-hydroxy-9H-fluoren-2-yl)acetamide, a compound notable for its complex structure, exhibits interesting solubility characteristics that can be influenced by various factors.

General Solubility Behavior

This compound tends to be soluble in:

  • Polar solvents - such as water and alcohols, due to the presence of the hydroxyl (–OH) group which can form hydrogen bonds.
  • Organic solvents - like dimethyl sulfoxide (DMSO) and acetonitrile, attributed to its aromatic backbone that can interact favorably with non-polar sections of these solvents.

Factors Influencing Solubility

Several factors can impact the solubility of N-(3-hydroxy-9H-fluoren-2-yl)acetamide:

  • Temperature - Generally, an increase in temperature may enhance solubility for this compound in various solvents.
  • pH of the solution - The solubility can fluctuate based on the ionization of the hydroxyl group, making it more soluble in more acidic or alkaline solutions.
  • Presence of other solutes - The addition of salts or other solutes can either enhance or impede solubility through phenomena like salting out.

In summary, the solubility of N-(3-hydroxy-9H-fluoren-2-yl)acetamide is quite dynamic, strongly dependent on the solvent system and external conditions. Its ability to dissolve in both polar and non-polar environments speaks to its versatility in the realm of chemical applications.

Interesting facts

Interesting Facts about N-(3-hydroxy-9H-fluoren-2-yl)acetamide

N-(3-hydroxy-9H-fluoren-2-yl)acetamide is a fascinating compound that showcases the intersection of structure and function in organic chemistry. Here are some engaging details about this compound:

  • Structure Insights: The presence of the fluorenyl group in the structure gives this compound unique properties. The fluorenyl moiety is a polycyclic aromatic hydrocarbon contributing to electronic delocalization, often resulting in distinctive optical behaviors.
  • Biological Relevance: Compounds related to N-(3-hydroxy-9H-fluoren-2-yl)acetamide have been investigated for their potential biological applications, including roles in drug development and biochemical research.
  • Synthesis: The synthesis of this compound typically involves multi-step synthetic pathways, highlighting the synthetic chemist's skills. Various reagents and conditions can lead to different yields and purities, making each synthesis an intriguing experiment.
  • Applications: Its derivatives have potential uses in fields such as materials science, where they might serve as intermediates in creating organic electronics or light-emitting diodes (OLEDs).
  • Research Potential: The study of N-(3-hydroxy-9H-fluoren-2-yl)acetamide opens avenues for further research into compounds with similar structures, particularly in exploring new functionalities and applications in medicinal chemistry.

In summary, N-(3-hydroxy-9H-fluoren-2-yl)acetamide is not just another compound; it represents a portal to understanding complex interactions in organic molecules and their implications in various scientific domains. As you explore its properties and applications, you may find yourself inspired by the intricate dance of atoms and the remarkable endeavors of synthetic chemists.

Synonyms
N-(3-hydroxy-9H-fluoren-2-yl)acetamide
inchi=1/c15h13no2/c1-9(17)16-14-7-11-6-10-4-2-3-5-12(10)13(11)8-15(14)18/h2-5,7-8,18h,6h2,1h3,(h,16,17
1838-56-8
N-(3-Hydroxy-2-fluorenyl)acetamide
3-Hydroxy-N-acetyl-2-aminofluorene
3-HO-AAF
3-Hydroxy-2-acetylaminofluorene
3-Hydroxy-2-acetamidofluorene
acetamide, N-(3-hydroxy-9H-fluoren-2-yl)-
2-Acetylamino-3-hydroxyfluorene
ACETAMIDE, N-(3-HYDROXYFLUOREN-2-YL)-
LCS7D8W9J5
CHEBI:34335
NSC-40564
NSC-46731
WLN: L B656 HHJ DQ EMV1
3-Hydroxyacetylaminofluorene
NSC 46731
CCRIS 2767
NSC 40564
BRN 2811033
N-9H-Fluoren-2-yl-3-hydroxyacetamide
Acetamide, N-9H-fluoren-2-yl-3-hydroxy-
UNII-LCS7D8W9J5
CHEMBL296830
DTXSID00939760
MNPABTKJCQDDNY-UHFFFAOYSA-N
Acetylamino-3-hydroxyfluorene, 2-
BAA83856
NSC40564
NSC46731
AKOS024337325
51480-57-0
N-(3-Hydroxy-9H-fluoren-2-yl)ethanimidic acid
Q27115997