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N-(3-isothiocyanatophenyl)acetamide

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Identification
Molecular formula
C9H8N2OS
CAS number
53695-25-3
IUPAC name
N-(3-isothiocyanatophenyl)acetamide
State
State

At room temperature, N-(3-isothiocyanatophenyl)acetamide exists in a solid state. This solid form is maintained under standard lab conditions, indicating its stability at ambient temperatures.

Melting point (Celsius)
122.00
Melting point (Kelvin)
395.15
Boiling point (Celsius)
333.00
Boiling point (Kelvin)
606.15
General information
Molecular weight
192.24g/mol
Molar mass
192.2400g/mol
Density
1.2820g/cm3
Appearence

N-(3-isothiocyanatophenyl)acetamide appears as an off-white solid powder. Its appearance can vary slightly depending on the purity and specific form, but it generally remains consistent with its characteristic pale coloration.

Comment on solubility

Solubility of N-(3-isothiocyanatophenyl)acetamide

N-(3-isothiocyanatophenyl)acetamide, a compound with potential utility in various chemical applications, demonstrates interesting solubility characteristics. Understanding its solubility is essential for predicting its behavior in different environments and contexts. Here are some key points about its solubility:

  • Solvent Dependency: The solubility of N-(3-isothiocyanatophenyl)acetamide can significantly depend on the solvent used. Generally, compounds of this nature are more soluble in polar solvents compared to nonpolar ones.
  • Temperature Influence: Like many organic compounds, its solubility can increase with rising temperature, allowing for better dissolution in solvent systems.
  • pH Considerations: The solubility may also vary with pH, especially if the functional groups can interact with protons, influencing solubility dynamics in acidic or basic conditions.
  • Precipitation Potential: When mixed with certain aqueous solutions, there could be a tendency for precipitation, which is crucial for practical applications in synthesis and formulation.

In summary, the solubility of N-(3-isothiocyanatophenyl)acetamide is a multifaceted aspect that hinges on several factors such as the choice of solvent, temperature, pH, and potential subsequent interactions. It is vital to perform solubility tests under specific conditions to tailor its application appropriately.

Interesting facts

Interesting Facts about N-(3-Isothiocyanatophenyl)acetamide

N-(3-Isothiocyanatophenyl)acetamide is a fascinating compound that falls under the category of isothiocyanates, known for their remarkable contributions to various fields, particularly in medicinal chemistry and agriculture. Here are some intriguing insights about this compound:

  • Biological Significance: Isothiocyanates are recognized for their potential anticancer properties. N-(3-Isothiocyanatophenyl)acetamide, like its relatives, may exhibit activity in inhibiting tumor growth and promoting apoptosis, making it a subject of interest in cancer research.
  • Flavor and Aroma: Compounds featuring isothiocyanate groups are often linked to the pungent aroma and flavor profile of cruciferous vegetables, such as mustard and broccoli. This compound's structural relationship hints at its possible sensory effects.
  • Mechanism of Action: The isothiocyanate functional group plays a crucial role in the biological activity of this compound. It has been observed to interact with various cellular pathways, potentially leading to various therapeutic effects.
  • Research Applications: N-(3-Isothiocyanatophenyl)acetamide can serve as a lead compound in the synthesis of new derivatives with enhanced biological activity. Its unique structure provides a scaffold for scientists to explore modifications that could improve efficacy and specificity.
  • Cultural Relevance: The presence of isothiocyanates in traditional diets has prompted inquiries into their protective roles against certain diseases. Understanding compounds like N-(3-Isothiocyanatophenyl)acetamide might give insights into the health benefits of consuming cruciferous vegetables.

In summary, N-(3-Isothiocyanatophenyl)acetamide is not just a chemical entity but a compound with the potential to contribute significantly to both scientific understanding and practical applications in health and agriculture. Its exploration can unveil numerous possibilities in the chemistry of life and nutrition.

Synonyms
N-(3-Isothiocyanatophenyl)acetamide
Acetamide, N-(3-isothiocyanatophenyl)-
3-Acetamidophenyl isothiocyanate
BRN 2643286
EINECS 221-536-3
DTXSID8062860
ISOTHIOCYANIC ACID, m-ACETAMIDOPHENYL ESTER
DTXCID4038348
221-536-3
3137-83-5
3'-Isothiocyanatoacetanilide
3-Isothiocyanatoacetanilide
ACETAMIDE,N-(3-ISOTHIOCYANATOPHENYL)-
SCHEMBL2921891
HLWVGQKSSIHUAX-UHFFFAOYSA-N
AKOS000212396
NS00029075
EN300-31003
G21047
Z317098542