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N-(3-nitrophenyl)acetamide

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Identification
Molecular formula
C8H8N2O3
CAS number
5576-01-8
IUPAC name
N-(3-nitrophenyl)acetamide
State
State

The compound is typically a solid at room temperature. It is stable under normal conditions but should be handled with care to avoid exposure to its potentially hazardous properties.

Melting point (Celsius)
177.00
Melting point (Kelvin)
450.15
Boiling point (Celsius)
316.00
Boiling point (Kelvin)
589.15
General information
Molecular weight
180.16g/mol
Molar mass
180.1570g/mol
Density
1.3376g/cm3
Appearence

N-(3-nitrophenyl)acetamide appears as a pale yellow crystalline solid. The yellow hue is indicative of the presence of the nitro group that absorbs certain wavelengths of light, imparting a characteristic color to the compound.

Comment on solubility

Solubility of N-(3-nitrophenyl)acetamide

N-(3-nitrophenyl)acetamide, a compound with interesting chemical properties, exhibits moderate solubility in various solvents. Its solubility characteristics can be summarized as follows:

  • Polar Solvents: It shows good solubility in polar protic solvents like water and alcohols, primarily due to the ability of the amide group to participate in hydrogen bonding.
  • Apolar Solvents: However, in non-polar solvents such as hydrocarbons, the solubility is notably reduced due to the lack of significant solvation interactions.
  • Temperature Effect: The solubility of N-(3-nitrophenyl)acetamide can also depend on temperature, generally increasing as temperature rises.

In summary, while N-(3-nitrophenyl)acetamide demonstrates effective solubility in polar environments, its performance diminishes in non-polar media. This behavior is crucial for its applications in various chemical processes and environments. Always consider compatibility with the solvent when utilizing this compound in experiments or industrial applications.

Interesting facts

Understanding N-(3-nitrophenyl)acetamide

N-(3-nitrophenyl)acetamide, a compound found in various chemical applications, offers a fascinating look at the intersection of organic chemistry and biological activity. This compound is particularly noteworthy due to its unique functional groups and properties.

Key Features of N-(3-nitrophenyl)acetamide:

  • Structural Characteristics: The presence of a nitro group (–NO2) on the aromatic ring enhances its reactivity and solubility in various organic solvents.
  • Biological Significance: Compounds similar to N-(3-nitrophenyl)acetamide are often studied for their potential roles as pharmaceuticals or agrochemicals, where they may exhibit antimicrobial or herbicidal properties.
  • Reactivity: The acetamide functional group can provide insight into conducting electrophilic aromatic substitutions, making it an interesting candidate for synthetic chemistry studies.

Researchers are particularly interested in the following attributes:

  1. Synthesis: Understanding the methods for synthesizing N-(3-nitrophenyl)acetamide can illuminate new pathways in organic synthesis.
  2. Mechanistic Insights: The interactions involving the nitrophenyl group are critical, as they affect the compound's reactivity and behavior in chemical reactions.
  3. Applications: Beyond its use in the laboratory for educational purposes, this compound may serve as a precursor in the manufacture of more complex chemicals used in diverse industries.

In the broader context of chemical research, N-(3-nitrophenyl)acetamide serves as an excellent example of how structural variations within organic molecules can lead to substantial differences in properties and applications. As professionals and students dive deeper into the world of organic chemistry, compounds like this one demonstrate the intricate relationships between structure, reactivity, and function in chemical compounds.

Synonyms
3-Nitroacetanilide
RefChem:90472
3'-Nitroacetanilide
122-28-1
N-(3-NITROPHENYL)ACETAMIDE
m-Nitroacetanilide
Acetamide, N-(3-nitrophenyl)-
N-Acetyl-m-nitroaniline
3-Nitro-N-acetylaniline
Acetanilide, 3'-nitro-
MFCD00017015
QGH8S22NBP
NSC-1314
N-{3-nitrophenyl}acetamide
UNII-QGH8S22NBP
Acetamide,N-(3-nitrophenyl)-
NSC 1314
EINECS 204-532-6
3\'-Nitroacetanilide
AI3-08832
Maybridge1_005437
3'-Nitroacetanilide, 97%
MLS000755735
SCHEMBL1248559
SCHEMBL6474687
M-NITROACETANILIDE [MI]
CHEMBL1568017
DTXSID5059539
SCHEMBL11262706
SCHEMBL28235900
HMS556P03
NSC1314
HMS2614A20
NSC99339
CCG-47377
NSC-99339
SBB065165
STK257092
AKOS000502795
FN70777
MS-1807
NCGC00246571-01
SMR000337404
SY070915
DB-371084
3 inverted exclamation mark -Nitroacetanilide
CS-0204902
N0106
NS00023983
ST45050639
VU0318314-2
D91639
AE-641/01922030
F242562
SR-01000636997
SR-01000636997-1
SR-01000636997-3
Q27287255
F3377-0746