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N-(3-oxotetrahydrothiophen-2-yl)acetamide

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Identification
Molecular formula
C6H9NO2S
CAS number
104318-76-7
IUPAC name
N-(3-oxotetrahydrothiophen-2-yl)acetamide
State
State

At room temperature, N-(3-oxotetrahydrothiophen-2-yl)acetamide is in a solid state. Its crystalline form makes it stable and typically non-volatile under standard conditions.

Melting point (Celsius)
105.00
Melting point (Kelvin)
378.15
Boiling point (Celsius)
284.20
Boiling point (Kelvin)
557.35
General information
Molecular weight
159.21g/mol
Molar mass
159.2110g/mol
Density
1.2978g/cm3
Appearence

N-(3-oxotetrahydrothiophen-2-yl)acetamide typically appears as a white to off-white crystalline powder. Its appearance can vary slightly depending on its purity and the presence of any impurities.

Comment on solubility

Solubility of N-(3-oxotetrahydrothiophen-2-yl)acetamide

The solubility of N-(3-oxotetrahydrothiophen-2-yl)acetamide (C6H9NO2S) is influenced by its chemical structure and functional groups. Here are some key points to consider:

  • Polarity: The presence of the acetamide group contributes to the overall polarity of the compound, enhancing its ability to dissolve in polar solvents like water.
  • Hydrogen Bonding: This compound can engage in hydrogen bonding due to the amide functional group, which often results in improved solubility in protic solvents.
  • Solvent Compatibility: While N-(3-oxotetrahydrothiophen-2-yl)acetamide is expected to be relatively soluble in water, it may exhibit varying solubility in organic solvents, with potential compatibility in polar aprotic solvents.

However, it is essential to remember that solubility can be influenced by several factors, such as temperature and pH. As a general examination of this compound indicates:

  1. The acetamide portion can interact favorably with solvent molecules.
  2. The thiophenyl ring may impart some hydrophobic characteristics, potentially affecting solubility.

In conclusion, while N-(3-oxotetrahydrothiophen-2-yl)acetamide demonstrates potential solubility in various solvents, its complete behavior can only be understood through experimental investigation under defined conditions. Overall, the interplay of functional groups and solvent properties is key to predicting solubility effectively.

Interesting facts

Interesting Facts About N-(3-oxotetrahydrothiophen-2-yl)acetamide

N-(3-oxotetrahydrothiophen-2-yl)acetamide is a fascinating compound that combines elements of both organic and sulfur chemistry, which opens up a variety of intriguing research avenues. Here are some noteworthy points:

  • Structural Diversity: This compound features a unique thiophene ring—a five-membered ring containing a sulfur atom—which contributes significantly to its chemical properties and potential applications.
  • Functional Groups: With the presence of both an amide and a ketone group, this compound showcases a rich site for chemical reactivity and synthesis, making it a versatile building block in medicinal chemistry.
  • Biological Relevance: Compounds that contain thiazolidine and thiophene derivatives have been studied for their potential biological activities, including antimicrobial and anti-inflammatory effects. Thus, exploring N-(3-oxotetrahydrothiophen-2-yl)acetamide could yield promising pharmacological applications.
  • Synthesis: The synthesis of such compounds often involves multi-step processes, requiring careful manipulation of reaction conditions and reagents to achieve desired intermediates and final products.
  • Potential Uses: Beyond pharmaceuticals, this compound can serve as a precursor in the synthesis of more complex molecules, further extending its utility across the field of organic chemistry.

The exploration of N-(3-oxotetrahydrothiophen-2-yl)acetamide not only embodies the rich landscape of organic synthesis but also highlights the continuous search for novel compounds in drug development. In the words of chemists: "Every compound tells a story, waiting for the right researcher to uncover its secrets."

Synonyms
n-(3-oxotetrahydrothiophen-2-yl)acetamide
Spectrum_001440
Spectrum2_001532
Spectrum3_001906
Spectrum4_000608
Spectrum5_001014
BSPBio_003472
KBioGR_001136
KBioSS_001920
DivK1c_000852
SPECTRUM1503205
SPBio_001344
CHEMBL5486919
SCHEMBL13930678
HMS502K14
KBio1_000852
KBio2_001920
KBio2_004488
KBio2_007056
KBio3_002976
NINDS_000852
XZPSMGBHBUQFHR-UHFFFAOYSA-N
HMS1922I07
Tox21 111388
CCG-39310
IDI1_000852
NCGC00095015-02
NCGC00095015-03