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N-(3-phenanthryl)acetamide

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Identification
Molecular formula
C16H13NO
CAS number
58154-62-0
IUPAC name
N-(3-phenanthryl)acetamide
State
State

At room temperature, N-(3-phenanthryl)acetamide exists as a solid. Its crystalline form may lead to it appearing as a powder or small chunks, depending on how it is processed or stored.

Melting point (Celsius)
169.00
Melting point (Kelvin)
442.15
Boiling point (Celsius)
375.00
Boiling point (Kelvin)
648.15
General information
Molecular weight
221.26g/mol
Molar mass
221.2610g/mol
Density
1.2340g/cm3
Appearence

N-(3-phenanthryl)acetamide is typically a crystalline solid with a white to off-white appearance. Its crystalline nature gives it a shiny, reflective surface when viewed under proper lighting conditions.

Comment on solubility

Solubility of N-(3-phenanthryl)acetamide

N-(3-phenanthryl)acetamide is a fascinating compound with its unique structural features influencing its solubility characteristics. When considering its solubility, there are several key aspects to take into account:

  • Polar vs. Nonpolar: The presence of the acetamide group contributes to some polarity, but the large phenanthryl group is largely nonpolar. This dual nature suggests limited solubility in polar solvents.
  • Solvent Interactions: It is expected to have higher solubility in organic solvents like chloroform or dichloromethane compared to water.
  • Temperature Dependency: Solubility can also fluctuate with temperature, often increasing at elevated temperatures. Thus, higher temperatures may promote dissolution in chosen organic solvents.
  • Impurities and Crystallization: Impure samples may exhibit irregular solubility behaviors due to crystallization of certain forms or complexes.

In summary, while N-(3-phenanthryl)acetamide displays limited solubility in polar solvents, its solubility profile in organic solvents is significantly better, thereby opening avenues for practical applications in synthetic chemistry and formulation technology.

Interesting facts

Interesting Facts about N-(3-phenanthryl)acetamide

N-(3-phenanthryl)acetamide is a fascinating compound that showcases the intriguing intersection of organic chemistry and biochemistry. Here are some intriguing aspects of this compound:

  • Structural Characteristics: The compound features a unique structure that includes a phenanthryl group, which is a polycyclic aromatic hydrocarbon. This structure contributes to its potential chemical reactivity and biological activity.
  • Applications in Research: N-(3-phenanthryl)acetamide can serve as an important intermediate in the synthesis of various biologically active molecules, highlighting its versatility in medicinal chemistry.
  • Potential Biological Activity: Compounds like N-(3-phenanthryl)acetamide are often of interest in the pharmaceutical field for their potential antimicrobial, anti-inflammatory, and analgesic properties. This opens doors for further research and development.
  • Exploration of Derivatives: The synthesis of derivatives from N-(3-phenanthryl)acetamide can lead to enhanced biological activities and selectivity, making it a valuable compound for drug discovery.
  • Research Tools: Chemical compounds with such aromatic structures can also be utilized in various analytical methods, including chromatography and spectroscopy, making them key players in chemical analysis.

In summary, N-(3-phenanthryl)acetamide exemplifies the rich chemistry found in organic compounds. As a member of the amide family, it provides numerous opportunities for exploration in both synthetic and analytical fields, making it an interesting topic for both scientific study and application.

Synonyms
N-3-Phenanthrylacetamide
N-3-Phenanthrenylacetamide
3-Acetylaminophenanthrene
3-Acetaminophenanthrene
Acetamide, N-3-phenanthrenyl-
4120-78-9
ACETAMIDE, N-3-PHENANTHRYL-
J8S9UC5ZUW
NSC 141584
BRN 2806961
UNII-J8S9UC5ZUW
NSC-141584
DTXSID30194123
4-12-00-03442 (Beilstein Handbook Reference)
DTXCID40116614
Acetamide, N-3-phenanthrenyl-(9CI)
3-Acetamidophenanthrene
N-(3-Phenanthryl)acetamide
NSC141584
2-acetylaminophenan-threne
SCHEMBL3952992
WLN: L B666J DMV1
FSGXZFQZAIBEDS-UHFFFAOYSA-N
AKOS024340419
DB-320354